Articles tagged "Heart/lung transplantation"

2019 American Transplant Congress
Increasing Doses of Pain Medications Pre-Heart Transplant as a Risk Factor for Outcomes after Transplant
K. Shah, D. H. Chang, J. Patel, R. J. Levine, S. Dimbil, E. Passano, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Chronic pain syndromes prior to heart transplantation (HTx) are not uncommon. However, the use of morphine equivalents in higher doses may be indicative of…
2019 American Transplant Congress
Anti-CD272 Antibody (6B2) Induced Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allograft
E. Yin, M. Uchiyama, Y. Yamamoto, M. Niimi
Teikyo University, Tokyo, Japan
*Purpose: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA; CD272) has been implicated in the regulation of autoimmune and may potentially play an important…
2019 American Transplant Congress
Amiodarone And Primary Graft Dysfunction In Heart Transplantation: Reality Or Myth?
M. Kittleson, J. Patel, D. H. Chang, E. Kransdorf, S. Dimbil, R. Levine, K. Yabuno, L. Czer, M. Hamilton, F. Esmailian, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Primary graft dysfunction (PGD) after heart transplantation (HTx) is seen in approximately 10-30% of patients immediately post-transplant. The cause of PGD is not clear…
2019 American Transplant Congress
Safety and Efficacy of Anti Xa Inhibitors Post-Transplant with Concomitant Calcineurin Inhibitors
K. A. McMurry¹, J. Shuster², K. Bain², T. Horwedel³, J. Hartupee²
¹Michigan Medicine, Ann Arbor, MI, ²Barnes-Jewish Hospital, St. Louis, MO, ³Veloxis Pharmaceuticals, Cary, NC
*Purpose: Despite demonstrated benefits of Anti-Xa Inhibitors (ATIs) in the general population, ATIs have not gained uniform acceptance in SOT due to lack of supportive…
2019 American Transplant Congress
Incidence and Risk of Allograft Rejection after Cardiac Transplantation in Left Ventricular Assist Device Patients
R. C. Patel¹, L. B. Cooper², S. D. Barnett², R. T. Cole², M. A. Psotka², A. Cochrane², S. Sinha², L. J. Bogar², S. S. Desai², P. Shah²
¹Virginia Commonwealth University School of Medicine, Inova Fairfax Hospital, Falls Church, VA, ²Department of Heart Failure and Transplant, Inova Heart and Vascular Institute, Falls Church, VA
*Purpose: Left ventricular assist devices (LVAD) are made of biomaterials that have been shown to cause allosensitization. Single center studies have suggested that patients bridged…
2019 American Transplant Congress
3-year Outcome Of Heart Transplantation In Patients With Amyloidosis
J. Patel, M. Kittleson, D. H. Chang, R. Levine, S. Dimbil, L. Czer, F. Esmailian, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Both amyloid light chain (AL) amyloidosis and transthyretin-related (TTR) amyloid are expanding indications for heart transplantation (HTx). In the past, AL amyloid, in particular,…
2019 American Transplant Congress
Correlation between Self-Reported Medication Adherence and Side Effects in Transplant Recipients
T. Harrison¹, K. Foster¹, N. Patel¹, H. Meadows¹, C. Perez¹, H. Corbo¹, J. Fleming¹, N. Pilch¹, D. DuBay², J. McGillicuddy², S. Nadig², V. Rohan², D. Taber¹
¹Pharmacy Services, Medical University of South Carolina, Charleston, SC, ²Transplant Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: Medication non-adherence (MNA) is a major risk factor for acute rejection and graft loss amongst all organ groups. It is unclear how medication side…
2019 American Transplant Congress
Does the Type of Pre-Heart Transplant Desensitization Therapy Affect 5-Year Post-Transplant Outcomes?
J. Patel, E. Kransdorf, R. Levine, S. Dimbil, L. Czer, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: As many patients with severe heart disease require mechanical circulatory support (MCS), the number of sensitized patients developing circulating antibodies continues to rise. In…
2019 American Transplant Congress
Reference Ranges Donor-Derived Cell-Free DNA in a Heart Transplant Population
A. Kao¹, S. Dholakia², M. Deng³
¹Saint Luke's, Kansas City, MO, ²CareDx, Brisbane, CA, ³University of Los Angeles, Los Angeles, CA
*Purpose: Elevations in donor-derived cell-free DNA (dd-cfDNA) ≥0.20 % in heart transplant recipients (HTR) has been shown to be associated with a probability of acute…
2019 American Transplant Congress
Exercise for Solid Organ Transplant Candidates and Recipients: A Joint Position Statement of the Canadian Society of Transplantation (CST) and Canadian Network for Rehabilitation and Exercise for Solid Organ Transplant Optimal Recovery (CAN-RESTORE)
T. Janaudis-Ferreira¹, S. Mathur², R. Deliva³, N. Howes⁴, C. Patterson⁵, A. Räkel⁶, S. So⁵, L. Wickerson⁷, M. White⁶, Y. Avitzur⁵, O. Johnston⁸, N. Heywood⁹, S. Singh⁷, S. Holdsworth¹⁰
¹School of Physical and Occupational Therapy, McGill University, Montreal, QC, Canada, ²University of Toronto, Toronto, ON, Canada, ³The Hospital for Sick Children, Toronto, ON, Canada, ⁴London Health Sciences Centre, London, ON, Canada, ⁵The Hospital For Sick Children, Toronto, ON, Canada, ⁶University of Montreal Hospital Centre, Montreal, QC, Canada, ⁷University Health Network, Toronto, ON, Canada, ⁸Vancouver General Hospital, Vancouver, BC, Canada, ⁹McGill University Health Centre, Montreal, QC, Canada, ¹⁰Canadian Donation and Transplantation Research Program, Edmonton, AB, Canada
*Purpose: Exercise training has been shown to be beneficial across several chronic disease groups that may lead to solid organ transplantation (SOT), and across organ…