ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Heart/lung transplantation"

  • 2022 American Transplant Congress

    The Post-operative Clinical Outcomes Of 59 Tanrp Cases In An International Cohort

    J. Louca1, N. Patel1, S. Messer2, J. Chindu2, S. Large2

    1Cambridge University, Cambridge, United Kingdom, 2Royal Papworth Hospital, Cambridge, United Kingdom

    *Purpose: Heart transplantation is an immensely effective service and is currently the only definitive treatment for heart failure. However, transplantation is limited by donor availability.…
  • 2022 American Transplant Congress

    Cardiomyocyte Cross-Sectional Area Increases After Orthotopic Cardiac Xenotransplantation and is Not Likely a Significant Contributor to Xenograft Growth up to 9 Months

    C. E. Goerlich1, B. Griffith1, J. Treffalls1, P. Hanna2, S. N. Hong2, A. K. Singh1, D. Ayares3, M. Mohiuddin1

    1Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Department of Medicine, Division of Cardiology, University of Maryland School of Medicine, Baltimore, MD, 3Revivicor, Inc., Blacksburg, VA

    *Purpose: Genetically engineered (GE) pigs are thought to be an alternative organ source for patients in end-stage heart failure unable to receive a timely allograft.…
  • 2022 American Transplant Congress

    Post Heart Transplant Outcomes of Desensitized Durable Mechanical Circulatory Support Patients

    J. Youn1, D. Kim2, J. Choi2, K. Kim1, I. Kim3, E. Kransdorf4, D. Chang4, M. Kittleson4, J. Patel4, R. Cole4, J. Moriguchi4, D. Ramzy5, F. Esmailian5, J. A. Kobashigawa4

    1Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of, 2Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, 3Keimyung University Dongsan Hospital, Daegu, Korea, Republic of, 4Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 5Department of Cardiothoracic Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: Desensitization therapy (DST) is considered to increase the chances of a negative crossmatch, to expand the number of suitable donors, and to improve post-transplant…
  • 2022 American Transplant Congress

    Direct Procurement of Heart and Lungs from a Controlled DCD Donor with Ongoing Abdominal Normothermic Regional Perfusion (aNRP) – A Synchronized Retrieval

    M. Husain1, A. Jothidasan1, C. Zeschky1, M. Osman2, M. Berman2, R. Gaurav3, A. Butler3, C. Watson3, B. Stutchfield4, I. Currie5, G. Oniscu5, J. Dunning1, U. Stock1

    1Department of Cardiothoracic Surgery, Transplantation and MCS, Royal Brompton & Harefield Hospitals Part of Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom, 2Department of Heart and Lung Transplant, Royal Papworth Hospital, Cambridge, United Kingdom, 3Roy Calne Transplant Unit, Department of Surgery, Addenbrookes Hospital, Cambridge University NHS Trust, Cambridge, United Kingdom, 4Edinburgh Transplant Centre, Royal Infirmary of Edinburgh, Edinburgh, Edinburgh, United Kingdom, 5Edinburgh Transplant Centre, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

    *Purpose: With the increased number of aNRP in controlled DCD donors comes a high demand for techniques to directly procure cardiothoracic organs during the aNRP.…
  • 2022 American Transplant Congress

    Using mTOR Inhibitor Nanoimmunotherapy to Induce Cardiac Allograft Tolerance in Non-Human Primates

    J. M. O1, P. M. Patel2, A. J. Teunissen3, C. L. Miller4, T. Costa1, M. Momodu1, D. Muldoon1, A. Dehnadi1, I. M. Hanekamp1, V. Pothula5, R. Sanchez-Tarjuelo6, G. Prevot6, W. J. Mulder6, J. Allan7, J. Ochando8, J. Madsen9

    1MGH, Boston, MA, 2Emory University, Atlanta, GA, 3Icahn School of Medicine at Mount Sinai, New york, NY, 4Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 5Icahn School of Medicine at Mount Sinai, New York, NM, 6Icahn School of Medicine at Mount Sinai, New York, NY, 7Massachusetts General Hospital - Harvard Medical S, Marblehead, MA, 8Mount Sinai School of Med, New York, NY, 9Massachusetts General Hospital, Boston, MA

    *Purpose: Though tolerance of kidney allografts has been consistently achieved using a mixed-chimerism model, cardiac allografts remain resistant to tolerance induction. Lipoprotein-based nanobiologics loaded with…
  • 2022 American Transplant Congress

    Pre-Emptive Rituximab Use for Epstein-Barr Virus (EBV) Viremia in Cardiothoracic Solid Organ Transplant Recipients

    B. Astorga, A. Loethen, L. Potter

    University of Chicago Medicine, Chicago, IL

    *Purpose: EBV viremia is associated with potentially life-threatening post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation. The utility of rituximab for treating EBV viremia in…
  • 2022 American Transplant Congress

    Status Exception Use in the New Seven-Tiered Heart Allocation System

    A. Plana1, A. Kanelidis1, W. F. Parker2, V. Jeevanandam3, C. Salerno3, B. Smith1, S. Kalantari1, S. Pinney1, J. Grinstein1

    1Cardiology, University of Chicago, Chicago, IL, 2Pulmonary/Critical Care, University of Chicago, Chicago, IL, 3Cardiac Surgery, University of Chicago, Chicago, IL

    *Purpose: The revised seven-tiered US heart allocation policy aimed to improve risk stratification to lower exception status use. However, recent literature has demonstrated that exceptions…
  • 2022 American Transplant Congress

    Dendritic Cell Senescence as a Key Contributor to Transplant Rejection

    J. Zhao1, X. Li1, S. Jung1, H. Zhang1, V. Kasinath1, J. Azzi1, P. Sage1, J. Bromberg2, R. Abdi1

    1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…
  • 2022 American Transplant Congress

    Fontan versus Non-Fontan Combined Heart-Liver Transplantation: Proceed but Cautiously

    I. A. Ziogas, W. K. Wu, M. Izzy, A. Shingina, C. Benson, K. L. Mishra, A. S. Shah, N. L. Do, W. G. McMaster, J. N. Menachem, S. P. Alexopoulos

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Combined heart-liver transplantation (CHLT) is increasing, corresponding with a growing prevalence of Fontan-associated end-organ damage. We aimed to describe our contemporary institutional experience with…
  • 2022 American Transplant Congress

    Cryptococcal Meningitis Presenting as SIADH in a Heart Transplant Recipient

    D. Blake, M. Ibrahim, E. Hamad, V. Rakita, J. Hoosain, H. Clauss

    Temple University Hospital, Philadelphia, PA

    *Purpose: Cryptococcal meningitis is a potentially fatal invasive fungal infection in solid organ transplant recipients. Meningoencephalitis is the most common clinical manifestation of cryptococcal infection.…
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