ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Heart"

  • 2020 American Transplant Congress

    Effect of Intravenous Ferric Gluconate on Post Heart Transplant Outcomes in Patients Bridged with Left Ventricular Assist Devices

    N. Krepostman, D. Kim, D. Masic, S. Kuhrau, J. Negrelli, M. Liebo, E. Raichlin, A. Heroux, H. Basha

    Internal Medicine, Loyola University Medical Center, Maywood, IL

    *Purpose: Our study examined the effect of intravenous (IV) ferric gluconate compared to oral iron repletion in reducing 30-day hospital readmissions and all-cause mortality in…
  • 2020 American Transplant Congress

    Multiplicity of Non-HLA Targets for Antibodies Developed in Association with Ventricular Assist Device Implantation

    M. Askar, D. Bhakta, H. Zafar, A. Alam, L. Pittmon, S. Kang, L. Klingman, J. Felius, S. M. Joseph, D. Wencker, D. M. Meyer, S. A. Hall

    Baylor University Medical Center and Baylor Scott & White Research Institute, Dallas, TX

    *Purpose: Multiple non-HLA antibodies have been implicated in poor outcomes after heart transplantation. Development of HLA and Non-HLA antibodies have been reported in association with…
  • 2020 American Transplant Congress

    Expression of Multiple Human Complement Regulatory Proteins Results in Prolonged Heterotopic Xenoheart Survival in an NHP Model

    K. Ahrens1, J. M. O1, W. Sommer2, D. Becerra1, P. M. Patel1, A. Dehnadi1, Y. Kan3, J. Layer3, J. Morrissette1, T. Costa1, I. M. Hanekamp1, J. S. Allan4, M. Youd3, R. N. Pierson5, W. Qin3, L. Burdorf5, A. M. Azimzadeh1, W. Westlin3, L. Yang3, J. C. Madsen5

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, 3eGenesis Inc., Cambridge, MA, 4Center for Transplantation Sciences, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, 5Center for Transplantation Sciences, Division of Cardiac Surgery, Massachusetts General Hospital, Boston, MA

    *Purpose: Advances in genome engineering technology allow for multiplex genetic modifications in pigs designed to address immunologic and coagulation incompatibilities in order to facilitate xenotransplantation.…
  • 2020 American Transplant Congress

    Characterization of Donor/Recipient Citizenship Status in Adult Heart Transplantation: A UNOS Registry Analysis

    K. Yang1, D. Miklin1, J. Pizula1, P. Genyk1, G. Liu2, A. Lee1, S. Nuno1, S. Hashmi1, J. Nattiv2, A. Kiankhooy3, L. Grazette2, M. Fong2, J. Rahman2, K. Pandya2, D. Vucicevic4, J. Li1, P. Kingsford1, P. Banankhah2, R. Chand5, A. Wolfson6, S. Shah1, A. Salimbangon7, C. Lum8, E. C. Depasquale2, A. S. Vaidya2

    1Keck Medicine of USC, Los Angeles, CA, 2Cardiology, Keck Medicine of USC, Los Angeles, CA, 3Cardiothoracic Surgery, Keck Medicine of USC, Los Angeles, CA, 4Newark Beth-Israel Medical Center, Newark, NJ, 5Harbor-UCLA Medical Center, Torrance, CA, 6University of Arizona Sarver Heart Center, Tucson, AZ, 7UCLA Medical Center, Los Angeles, CA, 8The Queen's Medical Center, Honolulu, HI

    *Purpose: There is a paucity of data describing heart transplant donor and recipient status. We therefore sought to examine the medical and demographic characteristics, and…
  • 2020 American Transplant Congress

    Computer-Assisted Cardiac Histologic Evaluation (CACHE) for Grading Cardiac Allograft Rejection

    E. Peyster1, S. ArabYarmohommadi2, A. Janowczyk2, M. Sekulic3, C. Cassol4, M. Feldman1, K. Margulies1, A. Madabhushi2

    1University of Pennsylvania, Philadelphia, PA, 2Case Western Reserve University, Cleveland, OH, 3University Hospitals Cleveland Medical Center, Cleveland, OH, 4Ohio State University, Columbus, OH

    *Purpose: Cardiac allograft rejection (CAR) is a serious concern in heart transplantation, occurring in 30-40% of patients during the first year. Endomyocardial biopsy (EMB) with…
  • 2020 American Transplant Congress

    Vesicle-Associated Tweak is Increased During Acute Cellular Rejection and Contributes to Endothelial Inflammation

    O. Gidlof, J. Sadrian, M. Grossi, S. Alcevska, J. Lundgren, G. Rådegran, G. Smith

    Cardiology, Lund University, Lund, Sweden

    *Purpose: Extracellular vesicles (EVs) are released from immune cells upon activation and play direct roles in allograft tolerance and rejection, in part through delivery of…
  • 2020 American Transplant Congress

    Management and Outcomes of Heart Transplant Recipients with Pre-Transplant Left Ventricular Assist Device Infections

    Z. Esquer Garrigos, P. Vijayvargiya, J. M. Stulak, S. A. Rizza, M. R. Sohail

    Infectious Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN

    *Purpose: Infection involving Left Ventricular Assist Device (LVAD) in patients who receive device therapy as a bridge to heart transplantation (HT) is a serious complication.…
  • 2020 American Transplant Congress

    The Liver Protects All? Donor Specific Antibody Formation in Heart-Liver Transplant Recipients

    A. W. Rogers1, T. N. Eagar2, C. Pham1, J. Krisl1, B. J. Pierce1, M. Moaddab1, R. Ghobrial3, B. Trachtenberg4, A. Bhimaraj4, A. O. Gaber3

    1Department of Pharmacy, Houston Methodist Hospital, Houston, TX, 2Department of Pathology, Houston Methodist Hospital, Houston, TX, 3Department of Surgery, Houston Methodist Hospital, Houston, TX, 4Houston Methodist Hospital, Houston, TX

    *Purpose: Donor specific antibodies (DSAs) are key in the development of antibody mediated rejection (AMR). Their role in decreased patient and graft survival has been…
  • 2020 American Transplant Congress

    Neonatal Tolerance Induction: Behaviours of Allogeneic Spleen and Bone Marrow Inocula in Neonatal Mice are Largely Determined by the Nature of Their CD8 T Cells

    R. A. Bascom, K. Tao, L. J. West

    University of Alberta, Edmonton, AB, Canada

    *Purpose: Injected adult allo-spleen (SC) and bone marrow cells (BMC) traffic to secondary lymphoid organs, proliferate and spread throughout neonatal mice; allo-SC consistently cause acute…
  • 2020 American Transplant Congress

    Combined Heart-Liver Transplantation: A Systematic Review of the Literature

    I. A. Ziogas1, D. Giannis2, P. Kapsampelis2, A. Giannopoulou2, A. Evangeliou2, K. S. Mylonas2, G. Tsoulfas3, L. K. Matsuoka1, M. I. Montenovo1, M. Izzy1, S. P. Alexopoulos1

    1Vanderbilt University Medical Center, Nashville, TN, 2Society of Junior Doctors, Athens, Greece, 3Aristotle University of Thessaloniki, Thessaloniki, Greece

    *Purpose: Combined heart-liver transplant (CHLT) has been increasingly utilized as the treatment of choice for candidates with dual end-stage organ disease. We aimed to assess…
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