Articles tagged "Heart"

2020 American Transplant Congress
Molecular Profiles of Injury in Heart Transplant Allograft: Relationship to Rejection, Ejection Fraction, and Survival
P. Halloran¹, J. Reeve², &. the INTERHEART Study Group³
¹University of Alberta, Edmonton, AB, Canada, ²Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: In previous studies we used microarray analysis of gene expression to identify rejection in heart transplant endomyocardial biopsies, and found that this also revealed…
2020 American Transplant Congress
Cardiac Allograft Tolerance Can be Achieved in Non-Human Primates via Transient Mixed Hematopoietic Chimerism and Erythropoietin Administration
K. Ahrens¹, J. M. O¹, W. Sommer², J. Morrissette¹, D. Becerra¹, P. M. Patel¹, A. Dehnadi¹, T. Costa¹, I. M. Hanekamp¹, J. S. Allan³, P. Cravedi⁴, P. S. Heeger⁴, G. Benichou¹, J. C. Madsen⁵
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, ³Center for Transplantation Sciences, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, ⁴Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, ⁵Center for Transplantation Sciences, Division of Cardiac Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: In non-human primates (NHPs), a mixed chimerism-based conditioning protocol results in kidney transplant tolerance and combined kidney and heart allograft tolerance. Previous work showed…
2020 American Transplant Congress
Wait Times in Pediatric Heart Transplant Candidates: Impact of Size and Blood Type Following the 2016 Allocation Policy Revision
R. J. Williams, M. Lu, L. A. Sleeper, S. Urbach, K. P. Daly
Department of Cardiology, Boston Children's Hospital, Boston, MA
*Purpose: To describe wait times for pediatric heart transplant (HT) candidates following institution of a new allocation system in March 2016.*Methods: The OPTN database was…
2020 American Transplant Congress
Heart Transplant Outcomes in Patients Who Receive Hepatitis B Virus-Positive Donor Hearts: A UNOS Registry Analysis
P. Genyk¹, K. Yang², R. Chand³, E. Depasquale¹
¹Keck Medicine of USC, Los Angeles, CA, ²Keck Medicine of USC, South Pasadena, CA, ³Harbor-UCLA Medical Center, Los Angeles, CA
*Purpose: Hepatitis B infection in post-transplant patients posed a challenge in the setting of immunosuppression. However, the advent of anti-viral therapy for HBV has made…
2020 American Transplant Congress
Choice of Mitral Valve and Aortic Valve for Replacement for ESRD Patients Eligible for Kidney Transplant: A USRDS Analysis
N. Sarabu¹, D. Ngendahimana², L. Al Dahabre³, K. Lentine⁴, K. Chavin¹, T. Srinivas¹, S. Deo²
¹University Hospitals Cleveland, Cleveland, OH, ²Case Western Reserve University, Cleveland, OH, ³University Hospitals of Cleveland, Cleveland, OH, ⁴Saint Louis University, Saint Louis, MO
*Purpose: Tissue valve (TiV) may be preferred over mechanical valve (meV) in ESRD patients for valve replacement. Among ESRD patients who are kidney transplant eligible,…
2020 American Transplant Congress
Prevalence of Depression and Antidepressant Use in Cardiac Transplant Candidates and Recipients
D. Wood¹, N. R. Konopasek², J. Powers², G. Kim², M. Marcangelo³, L. Lourenco¹
¹Pharmacy, University of Chicago Medicine, Chicago, IL, ²Cardiology, University of Chicago Medicine, Chicago, IL, ³Psychiatry, University of Chicago Medicine, Chicago, IL
*Purpose: A diagnosis of depression can have negative impacts such as graft loss, suicidal ideation, and mortality in patients pre- and post-heart transplantation (HT). This…
2020 American Transplant Congress
Three-Year Post-Transplant Outcome of Desensitized Mechanical Circulatory Support Patients Awaiting Heart Transplantation
J. Youn¹, R. Cole², D. Ramzy², E. Kim¹, J. Kobashigawa², J. Moriguchi²
¹Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ²Cedars-Sinai Heart Institute, Los Angeles, CA
*Purpose: Up to 30% of durable mechanical circulatory support (MCS) patients (pts) develop panel reactive antibody (PRA) screen >= 10%. In our program, desensitization (DS)…
2020 American Transplant Congress
Risk Factors for Adverse Clinical Outcomes amongst Renal Transplant Candidates Undergoing Screening Angiography for Coronary Artery Disease
M. Shah¹, A. Yung¹, J. Ebinger¹, J. Mirocha², E. Huang³, D. Geft¹, A. Peng³, B. Azarbal¹
¹Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, ²Cedars-Sinai Medical Center, Los Angeles, CA, ³Department of Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Patient’s with ESRD undergoing evaluation for kidney transplantation routinely undergo screening for coronary artery disease (CAD). Screening recommendations in this population differ between ACC/AHA…
2020 American Transplant Congress
Developing a Patient Specific Search of Heart Transplant Programs: Feedback from Heart Transplant Candidates and Recipients
W. T. McKinney¹, M. J. Bruin², C. R. Schaffhausen¹, S. Chu², J. Synder³, C. M. Martin⁴, T. Alexy⁴, B. L. Kasiske⁵, A. K. Israni¹
¹Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, ²College of Design, University of Minnesota, Minneapolis, MN, ³Hennepin Healthcare Research Institute, Minneapolis, MN, ⁴Cardiology Division, University of Minnesota Department of Medicine, Minneapolis, MN, ⁵Department of Medicine, Hennepin Healthcare, Minneapolis, MN
*Purpose: Patients seeking a heart transplant must contemplate numerous factors when making decisions regarding their care. Waitlist acceptance criteria, donor acceptance practices and outcomes often…
2020 American Transplant Congress
Impact of Pretransplant Malignancy on Heart and Lung Transplant Recipients
W. Kang¹, C. T. Sparrow², M. Kim¹, M. Rachid³, S. M. Soriano³
¹Internal Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, ²Department of Cardiology, University of Illinois College of Medicine at Peoria, Peoria, IL, ³Department of Pulmonology, University of Illinois College of Medicine at Peoria, Peoria, IL
*Purpose: The purpose of this study is to investigate pre-transplant malignancy (PTM) as a risk factor for worsened post-transplant prognosis in heart or lung transplant…

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