Articles tagged "Heart"

2015 American Transplant Congress
Cell Type of the Tolerizing Inoculum Plays a Role in the Formation of of Molecular Chimerism in Murine Neonatal Tolerance
X. Wang,¹ H. Mewhort,¹ S. Wang,¹ S. Tollenaar,¹ K. Tao,¹ L. West.^1,2,3
¹Department of Pediatrics, University of Alberta, Edmonton, AB, Canada; ²Department of Surgery, University of Alberta, Edmonton, AB, Canada; ³Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada.
Background: Heart transplantation is a lifesaving measure for many infants with severe congenital heart diseases. The acceptance of cardiac allografts without immunosuppression, or operational tolerance,…
2015 American Transplant Congress
Acute Kidney Injury and Outcome After Cardiac Transplantation
G. Fortrie,¹ O. Manintveld,² K. Caliskan,² M. Betjes.¹
¹Internal Medicine, Div. of Nephrology, Erasmus Medical Center, Rotterdam, Netherlands; ²Cardiology, Erasmus Medical Center, Rotterdam, Netherlands.
Background:Chronic kidney disease (CKD) is a frequently seen complication after cardiac transplantation and is partly explained by the prolonged use of calcineurin inhibitors. However, few…
2015 American Transplant Congress
Donor Dendritic Cells – Potential New Therapeutic Target in Transplantation
T. Ueno,^1,2,3 M. Yeung,¹ M. McGrath,¹ H. Iwamoto,³ Y. Nakamura,³ O. Konnno,³ Y. Kihara,³ T. Yokoyama,³ S. Ono,³ T. Ikeda,³ S. Kawachi,³ B. Ibrahim,¹ A. Chandraker.¹
¹Renal, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; ²Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; ³Transplant Surgery, Tokyo Medical University, Hachioji, Tokyo, Japan.
Background: It is clear that T cells play a central role in the process of allograft rejection. However, donor dendritic cells (dDC) are the most…