2015 American Transplant Congress
Kidney Vs. Heart Calculated PRA (CPRA) for Sensitized Heart Candidates: Does Donor Ethnic Distribution Make a Difference?
Background: CPRA, which is used for deceased donor (DD) kidney (KI) and pancreas/kidney-pancreas (PA/KP) allocation, is computed with KI DD HLA and ethnic frequencies. CPRA…2015 American Transplant Congress
Expedited Placement of Donor Hearts Increases Morbidity and Mortality Among Bypassed Potential Recipients – A Single Center Experience
Introduction: Organ procurement organizations (OPOs) may bypass potential recipients for expedited placement of donor organs. OPOs must provide justification for placing an organ outside the…2015 American Transplant Congress
Non-Cardiac Surgical Procedures After Left Ventricular Assist Device Implantation
Introduction: As left ventricular assist devices (LVAD) are increasingly used for patients with end-stage heart failure, the need for non-cardiac surgical procedures (NCS) in these…2015 American Transplant Congress
Are We Missing Cardiovascular Disease in Children Awaiting Liver Transplant?
Background: Cirrhotic cardiomyopathy, characterized by low systemic vascular resistance, is increasingly recognized as a complication of end stage liver disease. Yet optimal strategies to screen…2015 American Transplant Congress
Passive Administration of Antibodies to Cardiac Myosin Immediately Following Syngenic Cardiac Transplantation Result in Rejection
Surgery, Washington Univ Sch of Med, St. Louis, MO.
Introduction: Auto-immune responses to cardiac myosin, a heart specific protein has been proposed to be a target auto-antigen resulting in cardiac allograft vasculopathy following transplantation.…2015 American Transplant Congress
Chest Wall,Thymus, and Heart Transplant: Pushing the Boundary of Solid Organ Allotransplantation
Objective:The last 10 years have ushered in the clinical reality of upper extremity and face transplantation with animal models and basic science evidence to support…2015 American Transplant Congress
Investigation of Myocardial Function in Pediatric Transplant Recipients
Children's National, Washington, DC.
Purpose: In light of the major impact of cardiovascular morbidity on long-term transplant outcomes, a prospective controlled study was conducted to investigate changes in myocardial…2015 American Transplant Congress
Adoptive Transfer of T Cell Receptor-Transgenic (TCR-Tg) Cells Alters Endogenous Immune Responses During Acute Rejection
University of Chicago, Chicago, IL.
In addition to the therapeutic use of adoptive transfer of T cells to combat viral infections and malignancies in humans, adoptive transfer of T cell…2015 American Transplant Congress
Tolerance to Graft A-Antigens Following ABO-Incompatible Heart Transplantation (HTx) in a Blood Group A-Transgenic Mouse Model
Purpose: ABOi HTx can be performed safely in infants when ABO antibody (Ab) levels are low or absent. Following ABOi HTx, immune tolerance develops to…2015 American Transplant Congress
Cardiac Troponin T (cTNT) in the Assessment of Kidney Transplant (KTx) Benefit and Risk
1Nephrology, Mayo Clinic, Rochester, MN; 2Surgery, Mayo Clinic, Rochester, MN.
Introduction. Compared to waiting list (WL) KTx improves patient survival. However, mortality may increase early post-KTx. cTNT level at candidate evaluation is a strong, independent…