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American Transplant Congress abstracts

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Articles tagged "Heart"

  • 2015 American Transplant Congress

    Effects of Heart and Lung Co-Transplantation Across a Full MHC Barrier in Miniature Swine

    M. Madariaga, P. Spencer, S. Michel, G. La Muraglia II, M. O'Neil, E. Mannon, C. Leblang, I. Rosales, R. Colvin, D. Sachs, J. Allan, J. Madsen.

    Transplantation Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

    Background: We have previously shown that tolerance of heart allografts across a full MHC barrier can be induced in miniature swine after a 12-day course…
  • 2015 American Transplant Congress

    Cell Type of the Tolerizing Inoculum Plays a Role in the Formation of of Molecular Chimerism in Murine Neonatal Tolerance

    X. Wang,1 H. Mewhort,1 S. Wang,1 S. Tollenaar,1 K. Tao,1 L. West.1,2,3

    1Department of Pediatrics, University of Alberta, Edmonton, AB, Canada; 2Department of Surgery, University of Alberta, Edmonton, AB, Canada; 3Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada.

    Background: Heart transplantation is a lifesaving measure for many infants with severe congenital heart diseases. The acceptance of cardiac allografts without immunosuppression, or operational tolerance,…
  • 2015 American Transplant Congress

    Acute Kidney Injury and Outcome After Cardiac Transplantation

    G. Fortrie,1 O. Manintveld,2 K. Caliskan,2 M. Betjes.1

    1Internal Medicine, Div. of Nephrology, Erasmus Medical Center, Rotterdam, Netherlands; 2Cardiology, Erasmus Medical Center, Rotterdam, Netherlands.

    Background:Chronic kidney disease (CKD) is a frequently seen complication after cardiac transplantation and is partly explained by the prolonged use of calcineurin inhibitors. However, few…
  • 2015 American Transplant Congress

    Donor Dendritic Cells – Potential New Therapeutic Target in Transplantation

    T. Ueno,1,2,3 M. Yeung,1 M. McGrath,1 H. Iwamoto,3 Y. Nakamura,3 O. Konnno,3 Y. Kihara,3 T. Yokoyama,3 S. Ono,3 T. Ikeda,3 S. Kawachi,3 B. Ibrahim,1 A. Chandraker.1

    1Renal, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; 2Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; 3Transplant Surgery, Tokyo Medical University, Hachioji, Tokyo, Japan.

    Background: It is clear that T cells play a central role in the process of allograft rejection. However, donor dendritic cells (dDC) are the most…
  • 2015 American Transplant Congress

    Kidney Vs. Heart Calculated PRA (CPRA) for Sensitized Heart Candidates: Does Donor Ethnic Distribution Make a Difference?

    A. Kucheryavaya, L. Robbins Callahan, L. Edwards.

    UNOS, Richmond.

    Background: CPRA, which is used for deceased donor (DD) kidney (KI) and pancreas/kidney-pancreas (PA/KP) allocation, is computed with KI DD HLA and ethnic frequencies. CPRA…
  • 2015 American Transplant Congress

    Expedited Placement of Donor Hearts Increases Morbidity and Mortality Among Bypassed Potential Recipients – A Single Center Experience

    M. Peltz,1 M. Drazner,2 M. Jessen.1

    1Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX; 2Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX.

    Introduction: Organ procurement organizations (OPOs) may bypass potential recipients for expedited placement of donor organs. OPOs must provide justification for placing an organ outside the…
  • 2015 American Transplant Congress

    Non-Cardiac Surgical Procedures After Left Ventricular Assist Device Implantation

    S. Taghavi,1 S. Jayarajan,1 A. Mangi,2 E. Chan,1 E. Dauer,1 L. Sjoholm,1 A. Pathak,1 T. Santora,1 A. Goldberg,1 J. Rappold.1

    1Department of Surgery, Temple University School of Medicine, Philadelphia, PA; 2Division of Cardiac Surgery, Yale University School of Medicine, New Haven, CT.

    Introduction: As left ventricular assist devices (LVAD) are increasingly used for patients with end-stage heart failure, the need for non-cardiac surgical procedures (NCS) in these…
  • 2015 American Transplant Congress

    Are We Missing Cardiovascular Disease in Children Awaiting Liver Transplant?

    C. Villa,1 E. Hahn,1 J. Bucuvalas,2 K. Campbell,2 R. Hirsch,1 M. Lake,2 A. Lorts.1

    1Heart Institute, Cincinnati Childrens Hospital, Cincinnati, OH; 2Pediatric Liver Care Center, Cincinnati Childrens Hospital, Cincinnati, OH.

    Background: Cirrhotic cardiomyopathy, characterized by low systemic vascular resistance, is increasingly recognized as a complication of end stage liver disease. Yet optimal strategies to screen…
  • 2015 American Transplant Congress

    Passive Administration of Antibodies to Cardiac Myosin Immediately Following Syngenic Cardiac Transplantation Result in Rejection

    M. Sharma, M. Gunasekaran, N. Benshoff, W. Liu, A. Gelman, T. Mohanakumar.

    Surgery, Washington Univ Sch of Med, St. Louis, MO.

    Introduction: Auto-immune responses to cardiac myosin, a heart specific protein has been proposed to be a target auto-antigen resulting in cardiac allograft vasculopathy following transplantation.…
  • 2015 American Transplant Congress

    Chest Wall,Thymus, and Heart Transplant: Pushing the Boundary of Solid Organ Allotransplantation

    G. Torregrossa,1 M. Sosin,2 G. Gerosa,3 A. Dorafshar.2

    1Cardiothoracic Surgery, Mount Sinai Hospital, NYC, NY; 2Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD; 3Cardiac Surgery, Universita'di Padova, Padova, Italy.

    Objective:The last 10 years have ushered in the clinical reality of upper extremity and face transplantation with animal models and basic science evidence to support…
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