2015 American Transplant Congress
Effects of Heart and Lung Co-Transplantation Across a Full MHC Barrier in Miniature Swine
Background: We have previously shown that tolerance of heart allografts across a full MHC barrier can be induced in miniature swine after a 12-day course…2015 American Transplant Congress
Cell Type of the Tolerizing Inoculum Plays a Role in the Formation of of Molecular Chimerism in Murine Neonatal Tolerance
Background: Heart transplantation is a lifesaving measure for many infants with severe congenital heart diseases. The acceptance of cardiac allografts without immunosuppression, or operational tolerance,…2015 American Transplant Congress
Acute Kidney Injury and Outcome After Cardiac Transplantation
Background:Chronic kidney disease (CKD) is a frequently seen complication after cardiac transplantation and is partly explained by the prolonged use of calcineurin inhibitors. However, few…2015 American Transplant Congress
Donor Dendritic Cells – Potential New Therapeutic Target in Transplantation
Background: It is clear that T cells play a central role in the process of allograft rejection. However, donor dendritic cells (dDC) are the most…2015 American Transplant Congress
Kidney Vs. Heart Calculated PRA (CPRA) for Sensitized Heart Candidates: Does Donor Ethnic Distribution Make a Difference?
Background: CPRA, which is used for deceased donor (DD) kidney (KI) and pancreas/kidney-pancreas (PA/KP) allocation, is computed with KI DD HLA and ethnic frequencies. CPRA…2015 American Transplant Congress
Expedited Placement of Donor Hearts Increases Morbidity and Mortality Among Bypassed Potential Recipients – A Single Center Experience
Introduction: Organ procurement organizations (OPOs) may bypass potential recipients for expedited placement of donor organs. OPOs must provide justification for placing an organ outside the…2015 American Transplant Congress
Non-Cardiac Surgical Procedures After Left Ventricular Assist Device Implantation
Introduction: As left ventricular assist devices (LVAD) are increasingly used for patients with end-stage heart failure, the need for non-cardiac surgical procedures (NCS) in these…2015 American Transplant Congress
Are We Missing Cardiovascular Disease in Children Awaiting Liver Transplant?
Background: Cirrhotic cardiomyopathy, characterized by low systemic vascular resistance, is increasingly recognized as a complication of end stage liver disease. Yet optimal strategies to screen…2015 American Transplant Congress
Passive Administration of Antibodies to Cardiac Myosin Immediately Following Syngenic Cardiac Transplantation Result in Rejection
Surgery, Washington Univ Sch of Med, St. Louis, MO.
Introduction: Auto-immune responses to cardiac myosin, a heart specific protein has been proposed to be a target auto-antigen resulting in cardiac allograft vasculopathy following transplantation.…2015 American Transplant Congress
Chest Wall,Thymus, and Heart Transplant: Pushing the Boundary of Solid Organ Allotransplantation
Objective:The last 10 years have ushered in the clinical reality of upper extremity and face transplantation with animal models and basic science evidence to support…