Articles tagged "Heart transplant patients"

2021 American Transplant Congress
Assessing the Impact of Acute Major Adverse Kidney Events on Clinical Outcomes in Heart Transplant Recipients
J. E. Kelly¹, C. Perez¹, D. Taber¹, R. J. Tedford², B. McMahon², S. Alzaidi¹, H. B. Meadows¹
¹Pharmacy, MUSC Health, Charleston, SC, ²Medicine, MUSC Health, Charleston, SC
*Purpose: The purpose of this study was to elucidate contributors to the Major Adverse Kidney Events at 30 days (MAKE-30) outcome in heart transplant recipients…
2021 American Transplant Congress
Acute Dialysis, Mortality and Renal Failure After Heart Alone Transplant by Egfr and Dialysis Requirement in the United States
M. Aljuhani¹, T. Alexy¹, S. Jackson², C. Martin¹, R. Kandaswamy³, S. Riad¹
¹Medicine, University of Minnesota, Minneapolis, MN, ²Complex Care Analytics, Fairview Health Services, Minneapolis, MN, ³Surgery, University of Minnesota, Minneapolis, MN
*Purpose: We examined the early acute dialysis, 90-day mortality and one-year ESRD among OHT recipients by eGFR and dialysis requirement before transplantation.*Methods: Utilizing the SRTR…
2021 American Transplant Congress
Cyp3a5 Extensive Metabolizer Phenotype May be Associated with an Increase in Class 2 Donor Specific Antibodies and Antibody-Mediated Rejection
S. Mirza¹, N. Wilson², J. Van Zyl², P. Nguyen², T. Sam², S. Hall², M. Askar², R. Patel²
¹Texas Tech Univeristy Health Sciences Center Jerry H. Hodge School of Pharmacy, Dallas, TX, ²Baylor University Medical Center at Dallas, Dallas, TX
*Purpose: Tacrolimus (TAC) metabolism is highly dependent on CYP3A5, yet there is limited data on the effect of CYP3A5 genetic polymorphisms in heart transplant recipients…
2021 American Transplant Congress
Randomized Phase 3 Open-label Study of Maribavir vs Investigator-assigned Therapy for Refractory/resistant Cytomegalovirus Infection in Transplant Recipients: Subgroup Analyses of Efficacy by Organ
R. K. Avery¹, E. A. Blumberg², D. Florescu³, N. Kamar⁴, D. Kumar⁵, J. Wu⁶, A. Sundberg⁶
¹Johns Hopkins Hospital, Baltimore, MD, ²University of Pennsylvania, Philadelphia, PA, ³University of Nebraska School of Medicine, Omaha, NE, ⁴Hôpital de Rangueil, Toulouse, France, ⁵University Health Network, Toronto, ON, Canada, ⁶Shire Human Genetic Therapies, Inc., a Takeda company, Lexington, KY
*Purpose: Therapeutic options for refractory, with/without resistance (R/R), CMV infections are limited. We report organ type subgroup analyses from a large multi-center trial that studied…
2021 American Transplant Congress
The Co-Occurrence of Newly Developed HLA Donor Specific Antibody and Positive C3d/C4d Profiles Along with Immune Therapy Non-Compliance in Pediatric Heart Transplant Recipients is a High Risk Indicator for Patient Mortality
A. Zhang, C. Nasman, J. Allen, Y. Sun, D. Thomas, R. Rodriguez, C. Tan, G. Boyle
Cleveland Clinic Foundation Transplant Center, Cleveland, OH
*Purpose: Increasing evidence has implicated the deleterious effect of HLA donor specific antibody (DSA) in pediatric heart transplantation (PHTx). However, there are still insufficient research…
2021 American Transplant Congress
Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the US
K. A. Agarwal¹, H. Patel¹, N. Agrawal¹, F. Cardarelli¹, N. Goyal²
¹Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Nephrology, Tufts Medical Center, Boston, MA
*Purpose: Kidney dysfunction is not uncommon in patients with advanced heart failure. Simultaneous kidney and heart transplants (SKHT) have gained acceptance as treatment for patients…
2021 American Transplant Congress
The Perfect Candidate? The Stanford Integrated Psychosocial Assessment for Transplant
E. J. Henricksen¹, K. Stott², S. Ilango², Y. Moayedi³, K. Waddell⁴, H. I. Luikart⁴, J. Twiggs⁴, R. Lee¹, B. M. Zhang⁵, W. Hiesinger⁶, K. K. Khush⁴, J. J. Teuteberg⁴
¹Transplant, Stanford Healthcare, Stanford, CA, ²Social Work, Stanford Healthcare, Stanford, CA, ³Cardiology, University Health Network, Toronto, ON, Canada, ⁴Cardiology, Stanford University, Stanford, CA, ⁵Pathology, Stanford University, Stanford, CA, ⁶Cardiothoracic Surgery, Stanford University, Stanford, CA
*Purpose: The Stanford Integrated Psychosocial Assessment for Transplant (SIPAT) is a tool used to objectify and enhance the pre-transplant psychosocial evaluation. We sought to assess…
2021 American Transplant Congress
The Gut Microbiome in Heart Transplantation: A Prospective Pilot Study
M. Dela Cruz¹, E. Littmann², R. Nayak², C. Lehmann², R. Keskey³, T. Baker³, H. Lin², A. Bennett¹, G. Kim¹, S. Pinney¹, E. Pamer², A. B. Nguyen¹
¹Cardiology, University of Chicago, Chicago, IL, ²Medicine, University of Chicago, Chicago, IL, ³Surgery, University of Chicago, Chicago, IL
*Purpose: The contribution of the intestinal microbiome to alloimmunity in heart transplantation (HT) is unknown. We examined the fecal microbiota of HT recipients at the…
2021 American Transplant Congress
Intravenous Immunoglobulin in Heart Transplant Recipients with Hypogammaglobulinemia and Infection
J. Hoang, D. Nguyen, E. Graviss, M. Moaddab, A. Guha, J. Krisl
Houston Methodist Hospital, Houston, TX
*Purpose: Hypogammaglobulinemia (HGG) is a complication of solid organ transplantation which has been associated with increased risk of infections. HGG is commonly defined as a…
2021 American Transplant Congress
Adult Combined Liver-Heart Transplantation: The United States Experience
I. A. Ziogas¹, S. P. Alexopoulos¹, W. K. Wu¹, L. K. Matsuoka¹, M. A. Rauf¹, M. Izzy², R. Perri², K. H. Schlendorf³, J. N. Menachem³, A. S. Shah⁴
¹Division of Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, TN, ²Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, ³Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, ⁴Department of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Combined heart-liver transplantation (CHLT) is now being practiced with increasing regularity and improved outcomes in the United States. We performed the most comprehensive review…

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