ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Heart transplant patients"

  • 2021 American Transplant Congress

    Management of Drug Interactions During Protocolized Implementation of Posaconazole Immediately Post Heart Transplant

    G. Waldman, C. Rogers Marks, J. Clark, A. Woo, L. Irwin, A. Gerlach, G. D. Lewis, J. A. Fishman

    Massachusetts General Hospital, Boston, MA

    *Purpose: Posaconazole (POSA) is a strong CYP3A4 inhibitor known to increase tacrolimus exposure by up to 4-fold. Initiation requires empiric tacrolimus dose adjustment and close…
  • 2021 American Transplant Congress

    Primary Graft Dysfunction in a Risk-Stratified vs. Routine Induction Protocol in Heart Transplant Recipients

    J. S. van Zyl1, H. Zafar1, P. M. Nguyen2, J. Felius1, T. Sam3, S. A. Hall3

    1Baylor Scott & White Research Institute, Dallas, TX, 2Texas A&M University College of Medicine Health Science Center, Dallas, TX, 3Baylor Scott & White Health, Dallas, TX

    *Purpose: Treatment of left ventricular primary graft dysfunction (PGD-LV) is supportive in nature. We aim to evaluate whether a change in induction protocol from a…
  • 2021 American Transplant Congress

    Pregnancy Outcomes in 108 Heart Transplant Recipients

    L. A. Coscia1, A. Yusuf1, S. Rao2, S. Constantinescu3, M. J. Moritz4

    1Transplant Pregnancy Registry International, Philadelphia, PA, 2University of Virginia Heath System, Charlottesville, VA, 3Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 4Surgery, Lehigh Valley Health Network, Allentown, PA

    *Purpose: The purpose of this study was to describe 185 pregnancies in 108 heart transplant recipients.*Methods: Data regarding conceptions occurring between June 1987 and Dec…
  • 2021 American Transplant Congress

    Infection Rates in Heart Transplant Recipients With Combined Tacrolimus and Sirolimus at High versus Low Concentrations

    S. Goyal, J. Lyons, J. Negrelli, M. Liebo, A. Heroux

    Loyola University Medical Center, Maywood, IL

    *Purpose: Assess the impact of tacrolimus-sirolimus (TAC/SRL) concentration on infection rate in heart transplant recipients (HTR).*Methods: A retrospective review of HTR on TAC/SRL for ≥…
  • 2021 American Transplant Congress

    The Pathology of Heart Allograft Biopsies: Discrepancies in Interpretation Between Conventional Histology and the Molecular Microscope Diagnostic (MMDx®) System

    P. Randhawa1, A. Seitz2, Y. Huang1, B. Feingold2

    1Department of Pathology, Pittsburgh, PA, 2Pediatrics, University of Pittsburgh, Pittsburgh, PA

    *Purpose: There is growing interest in using transcriptomics to complement histologic evaluation of allograft hearts. The present study scrutinizes discrepancies between histologic and MMDx® systems…
  • 2021 American Transplant Congress

    Polyomavirus BK-Associated Nephropathy in Patients After Renal and Extrarenal Transplantation

    A. Schwarz1, J. Schmitz2, J. Braesen2, C. Bara3, M. Sauer4, H. Haller1, J. Gottlieb5

    1Nephrology Department, Hannover Medical School, Hannover, Germany, 2Institute of Pathology, Hannover Medical School, Hannover, Germany, 3Department of Thoracic Surgery, Hannover Medical School, Hannover, Germany, 4Department of Pediatric Hematology, Hannover Medical School, Hannover, Germany, 5Deparment of Pneumology, Hannover Medical School, Hannover, Germany

    *Purpose: Patients with non-renal organ transplantation (TX) may suffer BK-viral nephropathy (BKVN) of their own orthotopic kidneys. We aimed to know if these patients with…
  • 2021 American Transplant Congress

    Impact of Statin Intensity on the Incidence of Vascular Events and Graft Survival in Heart Transplant Recipients

    E. Kim1, I. Booth2, R. Madathil3, B. Ravichandran1, M. Demehin2, M. Plazak2

    1University of Maryland School of Pharmacy, Baltimore, MD, 2Pharmacy, University of Maryland Medical Center, Baltimore, MD, 3University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Cardiac allograft vasculopathy (CAV) limits long-term graft survival of heart transplant (HT) recipients. In addition to decreased synthesis of cholesterol, statins also demonstrate immunomodulatory…
  • 2021 American Transplant Congress

    Improving Well-being for Heart Transplant Recipients: Implementation of a Patient Navigator Program

    K. Ramonas, K. Ramonas

    Health Navigator Foundation, San Francisco, CA

    *Purpose: When surveyed, heart transplant recipients cited managing all their healthcare needs as a primary concern 83% of the time (n=23). To respond to this…
  • 2021 American Transplant Congress

    Assessing the Impact of Acute Major Adverse Kidney Events on Clinical Outcomes in Heart Transplant Recipients

    J. E. Kelly1, C. Perez1, D. Taber1, R. J. Tedford2, B. McMahon2, S. Alzaidi1, H. B. Meadows1

    1Pharmacy, MUSC Health, Charleston, SC, 2Medicine, MUSC Health, Charleston, SC

    *Purpose: The purpose of this study was to elucidate contributors to the Major Adverse Kidney Events at 30 days (MAKE-30) outcome in heart transplant recipients…
  • 2021 American Transplant Congress

    Acute Dialysis, Mortality and Renal Failure After Heart Alone Transplant by Egfr and Dialysis Requirement in the United States

    M. Aljuhani1, T. Alexy1, S. Jackson2, C. Martin1, R. Kandaswamy3, S. Riad1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Complex Care Analytics, Fairview Health Services, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: We examined the early acute dialysis, 90-day mortality and one-year ESRD among OHT recipients by eGFR and dialysis requirement before transplantation.*Methods: Utilizing the SRTR…
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