2015 American Transplant Congress
Electronic Health Service to Improve Therapeutic Drug Monitoring of Immunosuppressants
PurposeTherapeutic drug monitoring (TDM) of immunosuppressants is critical to avoid rejection or toxic side effects by under- or over-immunosuppression after heart transplantation (HTx). Hence, in…2015 American Transplant Congress
Acute Kidney Injury and Outcome After Cardiac Transplantation
Background:Chronic kidney disease (CKD) is a frequently seen complication after cardiac transplantation and is partly explained by the prolonged use of calcineurin inhibitors. However, few…2015 American Transplant Congress
Correlation of Longitudinal Gene-Expression Profiling Score to Cytomegalovirus Infection: Results from the Outcomes AlloMap® Registry
Purpose: Cytomegalovirus (CMV) infection has been implicated in the pathogenesis of allograft rejection, which is reflected by high gene-expression profiling (GEP) scores. In the IMAGE…2015 American Transplant Congress
The Impact of Administrating Everolimus Before Cytomegalovirus Infection to Prevent CMV Recurrence in Heart Transplant Recipients
Cardiovascular Surgery, Osaka University, Suita, Osaka, Japan.
Purpose – Cytomegalovirus (CMV) infection is a major complication in heart transplant recipients. Recent trials indicate that the use of the mammalian target of rapamycin…2015 American Transplant Congress
Clinical Use of Gene-Expression Profiling to Monitor for Rejection After Cardiac Transplantation – Which Patients and When?
Background: Gene-expression profiling (GEP), in place of endomyocardial biopsy, is increasing. GEP testing is intended for low-risk asymptomatic patients (pts); thus, the profile of pts…2015 American Transplant Congress
Clinically Relevant Wound Events With Everolimus-Based Immunosuppressive Regimen: Post-Hoc Analysis from a Randomized Heart Transplant Study
1For the A2309 Study Group, Vienna, Austria; 2Novartis, Basel, Switzerland.
Purpose: In the A2310 (NCT00300274) heart transplant (HTx) study with everolimus (EVR) vs mycophenolate mofetil (MMF), information on a broad spectrum of potential wound healing…2015 American Transplant Congress
Prevalence and Outcomes of Heart Transplantation in Children With Intellectual Disability
Background:Heart transplantation in children with intellectual disability (ID) is a controversial issue. Previous research on this population has been limited to small case reports.Objective:To describe…2015 American Transplant Congress
Late Rejection in Pediatric Heart Transplantation: The Importance of Medical Adherence
Division of Pediatric Cardiology, Columbia University, New York, NY.
While the incidence of early rejection (<1 yr post-transplant) after pediatric heart transplant (HT) has decreased, late rejection (> 1 yr post-transplant) remains a constant…2015 American Transplant Congress
A New Diagnostic Tool for Antibody Mediated Rejection in Heart and Lung Transplantation: Intragraft Donor Specific Anti-HLA Antibodies Detection
INTRODUCTION: Antibody mediated rejection (AMR) is one of the causes of dysfunction and graft loss. The limited histological features, with a weak sensibility of c4d,…2015 American Transplant Congress
Prevalence, Risk Factors, and Clinical Management of Chronic Renal Dysfunction in Heart Transplant Recipients
Background: Chronic kidney disease (CKD) is a frequent complication after heart transplantation. The magnitude of post-transplant CKD makes it necessary to characterize patients at increased…
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