2017 American Transplant Congress
CD4 T Cells and Co-Engagement with Foreign Protein Are Required in Antibody Response to Non-Self Blood Group A-Antigen.
Background: ABO-incompatible heart transplantation (ABOi HTx) is safe during infancy and allows increased donor access. B-cell tolerance develops to donor A/B-antigen(s) (Ag) after ABOi HTx…2017 American Transplant Congress
Two Months Delayed Induction of Mixed Chimerism After Heart and Kidney Cotransplantation in Nonhuman Primates.
Background We have previously achieved transplant tolerance in cynomolgus recipients cotransplanted with heart and kidney by treating recipients with standard triple drug immunosuppression for 4…2017 American Transplant Congress
Optimal Induction Therapy for Kidney Transplantation in Previous Heart Transplant Recipients: Analysis of OPTN/UNOS Registry.
Nephrology, Internal Medicine, Allegheny General Hospital, Pittsburgh, PA
It is unclear as to which induction agent is optimal for kidney transplant (KT) in prior heart transplant (HT) recipients who are already immunocompromised from…2017 American Transplant Congress
Identification of Promising Targets for Tolerance Induction Following Heart Transplantation.
Clinic for Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany
Introduction: Tolerance-inducing cell subsets which can support the organ acceptance following heart transplantation (HTx) can be found among dendritic cells (DCs) and regulatory T cells…2017 American Transplant Congress
Photopheresis for Recalcitrant Rejection After Heart Transplantation: Worthwhile?
Cedars-Sinai Heart Institute, Los Angeles
Background: Rejection is leading cause of mortality after heart transplantation (HTx). While the rates of rejection have declined over the past few decades from improvement…2017 American Transplant Congress
Refinement of an Old Faithful: A Standardized Flow Cytometry Approach to Measure Donor-Recipient Alloreactivity (a Pilot Study).
Purpose: Donor-specific antibody (DSA) and antibody (Ab)-mediated rejection are challenges in long-term outcomes and limit re-transplantation. Sensitizing events such as homografts in surgical procedures, assist…2017 American Transplant Congress
Improved Creatinine Immediately Post-LVAD Predicts Lower AKI Risk After Heart Transplant.
Background-Left ventricular assist device(LVAD) placement often improves renal function in patients with advanced heart failure. In those bridged to transplant with LVAD support it is…2017 American Transplant Congress
Evaluation of the Conversion from Brand Name to Generic Immunosuppression in Hospitalized Organ Transplant Recipients.
Purpose: Safe and effective immunosuppressant medications are critical to accomplish good graft and patient survival rates. The availability of “AB-rated” generic immunosuppression affords the opportunity…2017 American Transplant Congress
Longer Ischemic Time Is Associated with Late Graft Dysfunction in Pediatric Heart Transplant Recipients.
1Medical University of South Carolina, Charleston, SC; 2UT Southwestern, Dallas, TX
Introduction: The purpose of this study was to investigate associations between clinical factors and cardiac function as measured by pressure-volume loops (PVL) in a pediatric…2017 American Transplant Congress
Rates of Lost to Follow-Up Among Pediatric Heart, Kidney, and Liver Transplant Recipients.
Background. Pediatric transplant recipients are typically transitioned to adult transplant programs for post-transplant care after age 18. For pediatric kidney (KI) recipients transitioning to adult…
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