2018 American Transplant Congress
Most Pediatric Transplant Centers Are Underperforming and in Proximity to Higher Volume Centers
Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.
Purpose. Many research studies have shown that low case volume has been associated with worse survival outcomes in each type of pediatric solid organ transplant.…2018 American Transplant Congress
Congestive Hepatic Fibrosis: Correlation with Cardiac Hemodynamics and Changes after VAD or Cardiac Transplant
Background: Chronic heart failure causes chronic passive congestion of liver that can progress to advanced fibrosis. Liver biopsy is performed for assessment of fibrosis to…2018 American Transplant Congress
Financial Impact of Testing Standardization for Solid Organ Transplant Recipients
Background: Infection and bone marrow suppression surveillance is common practice in transplant recipients. Ordering of inappropriate lab tests can lead to repetitive blood draws, higher…2018 American Transplant Congress
Renal-Sparing Protocol May Be Harmful If Performed Early Post-Heart Transplant
Cedars Sinai Medical Center, Los Angeles, CA.
Purpose: Calcineurin inhibitors (CNIs) are associated with nephrotoxicity. Renal sparing protocol (RSP) with CNI free regimen using mycophenolate and a proliferation signal inhibitor may improve…2017 American Transplant Congress
Primary Graft Dysfunction Post Heart Transplantation: Is There Greater Risk for De Novo Donor-Specific Antibody Development?
Cedars-Sinai Heart Institute, Los Angeles
Background: Primary graft dysfunction (PGD) may occur in up to 30% of heart transplant recipients and has been associated with increased mortality. The development of…2017 American Transplant Congress
Impact of Dialysis During the Transplant Admission on Transplant and Post-Transplant Cost of Care.
This study examines the impact of dialysis during the transplant admission on total cost of transplant and one year post-transplant care for kidney, liver, and…2017 American Transplant Congress
Alemtuzumab Use in a Single Center Pediatric Heart Transplant Cohort.
Purpose: To describe the use and complications of alemtuzumab (AMB), a CD52 monoclonal antibody, in pediatric heart transplant (HT) patients (pt).Methods: Retrospective chart review of…2017 American Transplant Congress
Time to First Therapeutic Tacrolimus Level: What Impact Does It Have After Heart Transplantation?
University of Pittsburgh Medical Center, Pittsburgh, PA
Purpose: Appropriate time to therapeutic immunosuppression levels is not well defined. The purpose of this study is to investigate outcomes related to time to therapeutic…2017 American Transplant Congress
Exploring Differential Antibody Response to Bortezomib in Heart Transplantation.
Northwestern University, Chicago, IL
Twelve heart transplant candidates (2013-2016) received Bortezomib (BTZ) for desensitization. Differential antibody (Ab) response was observed. BTZ cycles consisted of 4 injections of 1.3 mg/m2;…2017 American Transplant Congress
Impact of mTOR-Inhibition on Tolerance-Induction Following Heart Transplantation.
Clinic for Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany
Introduction: The mammalian target of rapamycin (mTOR) is a central regulator of the immune system and therefore one target of immunosuppressive drug therapy. Tolerance-inducing properties…
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