Articles tagged "Heart transplant patients"

2018 American Transplant Congress
Early Adjunctive Treatment with Human Cytomegaly Virus (CMV) Immunoglobulin Increased CMV-Free Survival after Heart Transplantation
M. Barten,¹ C. Neumaier,¹ A. Bernhardt,¹ M. Rybczynski,² R. Plaetke,³ H. Reichenspurner.¹
¹Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany; ²General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany; ³Institute of Medical Biometry and Epidemiology, University Hospital Eppendorf Hamburg, Hamburg, Germany.
Purpose: There is still an ongoing discussion whether a prophylactic or a preemptive therapy against cytomegalovirus (CMV) is superior to reduce the incidence of CMV…
2018 American Transplant Congress
High Frequency of HLA-DQ De Novo Donor Specific Antibodies is Independent of the Number of Mismatches in Heart Transplant
X. Zhang,¹ E. Kransdorf,² J. Patel,² J. Kobashigawa.²
¹HLA and Immunogenetics Laboratory/ Comprehensive Transplant Center, Cedars-Sinai Health Systems, Los Angeles, CA; ²Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA.
Aim: Development of de novo donor specific antibodies (DSA) after heart transplant is associated with an increased risk of allograft failure. The aim of this…
2018 American Transplant Congress
Kidney Graft Outcomes in Combined Heart-Kidney Transplantation: A UNOS Database Analysis 2000-2015
A. Riaz, O. Adebiyi, D. Mishler, M. Yaqub, T. Taber, A. Sharfuddin.
Indiana University, Indianapolis.
Background: Combined Heart-Kidney Transplantation (CHKT) is the optimal therapy for patients with advanced renal dysfunction. Our aim was to analyze kidney specific graft outcomes in…
2018 American Transplant Congress
Outcomes after Cardiac Transplantation for Adult Congenital Heart Disease in the Modern Era
X. Zeng,¹ R. Vela,² J. Pruszynski,² J. Martinez,² S. Ring,² M. Peltz.²
¹Surgery, University of Texas Southwestern Medical Center, Dallas, TX; ²Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallss, TX.
Background: More patients with congenital heart disease (CHD) are surviving into adulthood and require heart transplantation. These patients historically experienced worse survival early after transplantation.…
2017 American Transplant Congress
Primary Graft Dysfunction After Pediatric Heart Transplant.
K. Mowers, K. Simpson, P. Eghtesady, O. Petrucci, C. Canter, C. Castleberry.
Pediatric Cardiology, Washington University School of Medicine, St. Louis, MO
Background: Primary graft dysfunction (PGD), as defined by ISHLT Consensus Guidelines, has been associated with worse outcomes in adult heart transplant recipients, even in patients…
2017 American Transplant Congress
Improvement of Cyclosporine A Dosing Strategy to Enhance Medication Adherence.
M. Barten,¹ E. Harmel,¹ M. Goldmann,¹ F. Wagner,¹ H. Reichenspurner,¹ M. Rybczynski.²
¹Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany; ²General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany
Background: It is known that the number of daily pills is crucial for medical adherence of patients after heart transplantation (HTx). For cyclosporine A (CsA)…
2017 American Transplant Congress
Comparing the Role of Post-Transplant Readmissions and Bed Days on Total One Year Cost of Care.
W. Bannister,¹ M. Schnitzler,² J. Tao,¹ A. Bonagura,¹ B. Laihinen,¹ F. Irwin,¹ C. Horstman.¹
¹Complex Medical Conditions, Optum, UnitedHealth Group, Eden Prairie, MN; ²Surgery, St. Louis University, St. Louis, MO
This study examines the marginal impact of readmissions and total bed days during the 90-day period following transplant in order to better understand drivers of…
2017 American Transplant Congress
Timing, Frequency, and Precipitating Factors of Early Readmission After Heart Transplant.
J. Van Liew, L. Potter, N. Uriel, L. Lourenco.
University of Chicago Medicine, Chicago, IL
Purpose: Early hospital readmission after organ transplantation, defined as readmission within 30 days of discharge, has been found to be associated with increased morbidity and…
2017 American Transplant Congress
Is Thymic Function Determining Rejection Onset in Heart Transplantation?
A. Sannier,^1,2 R. Dorent,^1,3 M. Le Borgne,¹ N. Stroumza,¹ J. Senemaud,¹ L. Louedec,¹ F. Andreata,¹ A. Gaston,¹ C. Deschildre,¹ P. Nataf,^1,3 A. Couvelard,² G. Caligiuri,¹ A. Nicoletti.¹
¹Inserm U1148, Diderot University, Paris, France; ²Pathology Department, Bichat Hospital, Paris, France; ³Cardiac Surgery Department, Bichat Hospital, Paris, France
The thymus is the primary site of T cell development, involuting into fatty tissue in adults. Thymic function persists in the adulthood and may be…
2017 American Transplant Congress
CD16+ Monocytes and Skewed Macrophage Polarization Towards M2 Type Hallmark Heart Transplant Acute Cellular Rejection.
T. van den Bosch,¹ K. Caliskan,² M. Kraaij,¹ A. Constantinescu,² O. Manintveld,² P. Leenen,³ J. von der Thüsen,⁴ M. Clahsen-van Groningen,⁴ C. Baan,¹ A. Rowshani.¹
¹Internal Medicine and Transplantation, Erasmus University Medical Center, Rotterdam, Netherlands; ²Cardiology, Erasmus University Medical Center, Rotterdam, Netherlands; ³Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; ⁴Pathology, Erasmus University Medical Center, Rotterdam, Netherlands
Purpose: During acute heart transplant rejection, infiltration of lymphocytes and monocytes is followed by endothelial injury and eventually myocardial fibrosis. To date, no information is…