2018 American Transplant Congress
Impact of Pre-Transplant Non-Dialysis Renal Dysfunction in Heart Transplant Recipients on Post-Transplant ESRD: A UNOS Database Analysis
Medicine, Loyola University Medical Center, Maywood, IL.
Dialysis prior to heart transplant (HTx) is a strong predictor of patient death and is a common indication for simultaneous heart/kidney transplantation (SHK). The association…2018 American Transplant Congress
Combined Heart–Kidney Compared to Isolated Heart Transplant in Patients with Chronic Kidney Disease – A Single Center Experience
Tufts University School of Medicine, Boston, MA.
Background: Severe irreversible renal dysfunction has been a contraindication for heart transplant (HTx); however, combined heart-kidney transplant (HKTx) is an accepted therapeutic option for concomitant…2018 American Transplant Congress
Impact of Infections on Patients with Left Ventricle Assist Devices(LVAD): Allo-Sensitization and Heart Transplantation
Virginia Commonwealth University, Richmond.
Background: The impact of post-LVAD infections on allosensitization and heart transplantation (HT) is unknown. High levels of panel reactive antibodies (PRA) preclude HT but the…2018 American Transplant Congress
Long-Term Success of Treatment for Cardiac Transplant AMR May Depend Upon Suppressing Class II Donor Specific Antibodies
Antibody mediated rejection (AMR) in cardiac transplant (tspt) patients (pts) is primarily mediated by donor specific antibodies (DSAs) and associated with reduced long-term graft survival.…2018 American Transplant Congress
Risk of Infection in Treatment of Acute Cellular Rejection in Heart Transplant Recipients
Tampa General Hospital, Tampa, FL; University of North Carolina, Chapel Hill, NC.
There has been no publication of the incidence of infection (infxn) after the treatment of acute cellular rejection (ACR) in heart transplant recipients (HTR). We…2018 American Transplant Congress
The Utility of a CD31/CD68 Dual Immunohistochemical Stain to Improve Accurate Diagnosis of Antibody Mediated Rejection in Cardiac Transplantation
Thoracic Pathology, University of Texas Southwestern Medical Center, Dallas, TX.
Antibody mediated rejection (AMR) occurs in 10%-20% of cardiac transplant patients and is associated with increased mortality. The endomyocardial biopsy, used to identify microvascular injury…2018 American Transplant Congress
The Overriding Importance of HLA-DR Donor-Specific Antibody That is Correlated to CAV after Heart Transplant
Cedars Sinai Medical Center, Los Angeles.
Purpose: Class II donor specific anti-HLA antibodies (DSA) have been correlated to subsequent CAV development. More specifically, HLA-DQ has been most reported for CAV development.…2018 American Transplant Congress
Decreased Post Heart Transplant Survival with Epstein-Barr Virus Mismatch in the Current Era
Cedars Sinai Medical Center, Los Angeles.
Purpose: Epstein-Barr virus (EBV) has been implicated in a multitude of cancers, including B-cell lymphoma, Burkitt's lymphoma, CNS lymphoma, gastric cancer and nasopharyngeal carcinoma. Previous…2018 American Transplant Congress
Elevated Serum Penteraxin in Cardiac Allograft Antibody Mediated Rejection: From Cytokine Arrays to Patients with ABMR
Pentraxin 3 (PTX3) is soluble protein that has been implicated in in atherosclerosis, endothelial function, hypertension, myocardial infarction and angiogenesis (Fornai et al., 2016). We…2018 American Transplant Congress
Urinary Cell Cycle Arrest Biomarkers as Early Predictors of Acute Kidney Injury Following Advanced Cardiac Replacement Therapies
Baylor University Medical Center, Dallas, TX.
Background: Current strategies to detect acute kidney injury (AKI) after cardiothoracic surgery rely on elevations in serum creatinine and diminished urine output, which are insensitive…
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