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American Transplant Congress abstracts

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Articles tagged "Heart transplant patients"

  • 2018 American Transplant Congress

    A Review of Pediatric Drug Development Programs and FDA Labeling for Immunosuppressive Drugs in Organ Transplant Patients

    G. Burckart,1 M. Cavaillé-Coll,2 A. Duong,3 L. Hothem,4 R. Albrecht.2

    1Office of Clinical Pharmacology, Office of Translational Science, CDER, US Food and Drug Administration, Silver Spring, MD; 2Division of Transplant and Opthalmology Products, Office of New Drugs, CDER, US Food and Drug Administration, Silver Spring, MD; 3Tauro University, New York, NY; 4University of North Carolina, Chapel Hill, NC.

    The development of drugs for organ transplantation spanned the time before and after pediatric regulatory requirements under the Best Pharmaceuticals for Children Act (BPCA) and…
  • 2018 American Transplant Congress

    Heart and Lung Transplantation Outcomes in HIV-Positive Recipients

    C. Koval,1 M. Malinis,2 N. Mueller,3 J. Krisl,4 M. Hannan,5 P. Grossi,6 S. Huprikar.7

    1Infectious Diseases, Cleveland Clinic, Cleveland, OH; 2Infectious Diseases, Yale University, New Haven, CT; 3Infectious Diseases, University Hospital Zurich, Zurich, Switzerland; 4Pharmacy, Houston Methodist Hospital, Houston, TX; 5Infectious Diseases, Mater Hospital, Dublin, Ireland; 6Infectious Diseases, University Insubria, Varese, Italy; 7Infectious Diseases, Mount Sinai Hospital, New York, NY.

    Purpose: Data for HIV+ patients receiving heart (HT) or lung transplantation (LT) are limited but appear to demonstrate acceptable outcomes. We aimed to add to…
  • 2018 American Transplant Congress

    Pre-Transplant Memory Patients Even without Detected Antibody Are at Rejection Risk in the First-Year after Heart Transplantation

    J. Patel, M. Kittleson, E. Kransdorf, R. Levine, S. Dimbil, D. Geft, D. Chang, L. Czer, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: Patients (pts) with prior transplants, blood transfusions, and pregnancies awaiting heart transplantation (HTx) have potential to develop circulating anti-HLA antibodies (HLA Abs). Pts at…
  • 2018 American Transplant Congress

    The Effect of Pre-Transplant Insomnia and Post-Transplant Insomnia on Survival among Solid Organ Recipients

    K-.F. Lee,2 Y. Tsai,1 C. Lin,1 C-.B. Hsieh,3,5 S. Wu,4 T. Chen,5 Y-.C. Lin,1 W-.H. Lee,6,7 F. Lin,8 C. Tsai.1,9,10

    1Cardiovascular Surgery, Tri-Service General Hospital, Taipei, Taiwan; 2Biobank Management Center, Tri-Service General Hospital, Taipei, Taiwan; 3General Surgery, Hualien Armed Forces General Hospital, Hualien County, Taiwan; 4Urology, Tri-Service General Hospital, Taipei, Taiwan; 5General Surgery, Tri-Service General Hospital, Taipei, Taiwan; 6Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 7Pathology, Taipei Medical University-Shuang Ho Hospital, New Taipei, Taiwan; 8Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 9Cardiovascular Surgery, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan; 10Graduate Institute of Pharmacology, National Defense Medical Center, Taipei, Taiwan.

    BackgroundBecause studies about insomnia among organ recipients were scarce, we used National Health Insurance Research Database (NHIRD) between 2001 and 2012 to understand how pre-transplant…
  • 2018 American Transplant Congress

    Early Results from USHER: A Pilot Trial of Transplanting HCV-Infected Hearts into HCV-Negative Recipients Followed by Anti-Viral Therapy

    R. McLean, P. P. Reese, M. Acker, P. Abt, A. Sicilia, N. Hornsby, P. Atluri, K. R. Reddy, E. Blumberg, V. Van Deerlin, D. S. Goldberg.

    UPENN, Philadelphia.

    Background: In 2016, over 600 hearts from deceased donors with active or prior hepatitis C virus (HCV) infection were discarded; most were otherwise good quality,…
  • 2018 American Transplant Congress

    Safety and Efficacy of Rabbit Anti-Thymocyte Globulin Induction in Pediatric Patients Undergoing Cardiac Transplantation

    M. Sell,1 A. Haney,1 K. Sprott,1 A. Burnette,2 H. Henderson,2 A. Savage.2

    1Pharmacy, Medical University of South Carolina, Charleston, SC; 2Cardiac Transplant, Medical University of South Carolina, Charleston, SC.

    Purpose: Limited data are available in pediatric cardiac transplant patients that focus on the safety and efficacy of rabbit anti-thymocyte globulin (rATG) induction therapy. The…
  • 2018 American Transplant Congress

    Impact of Influenza Vaccine Implementation by Transplant Pharmacy in Solid Organ Transplant Recipients

    S. Gattis,1 I. Yildirim,1,2 S. Serluco,1 C. McCracken,2 R. Liverman.1

    1Children's Healthcare of Atlanta, Atlanta, GA; 2Emory University School of Medicine, Atlanta, GA.

    Background: In solid organ transplant (SOT) recipients, influenza infection can lead to subsequent graft dysfunction and mortality. In an effort to increase vaccination rates, transplant…
  • 2018 American Transplant Congress

    Isolation and Profiling of miRNAs from Formalin Fixed Paraffin Embedded Endomyocardial Tissues from Human Heart Transplant Recipients

    R. Nog,1,2 C. Gupta,1,2 J. Fallon,1,2 J. Panza,1,2 N. Haque.2

    1Westchester Medical Center, Valhalla, NY; 2New York Medical College, Valhalla, NY.

    Allograft rejection is a common complication post heart transplant (HTx) and can be confirmed by endomyocardial biopsy (EBx) only. There is however an increasing need…
  • 2018 American Transplant Congress

    Is Renal Function after Heart Transplantation an Issue for Patients with Cardiac Amyloidosis?

    J. Patel, M. Kittleson, E. Kransdorf, R. Levine, S. Dimbil, D. Geft, D. Chang, L. Czer, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: Cardiac amyloidosis (CA) (AL and ATTR) is an expanding indication for transplantation. Post-transplant renal function may be affected numerous factors including pre-transplant cardiorenal syndrome,…
  • 2018 American Transplant Congress

    Donor Bacteremia Does Not Impact Survival Following Heart Transplantation: A UNOS Registry Review

    S. Hirji, A. Woolley, M. Pelletier, P. Shekar, F. Yazdchi, H. Mallidi, S. Singh.

    Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, MA.

    Background: There is a reluctance to transplant organs from donors who are bacteremic due to concern for transmission of the infection to the recipient leading…
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