2020 American Transplant Congress
First Experience with a New Storage Device for Cold Heart Preservation
Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
*Purpose: The standard technology for heart preservation for transplantation is cold static storange on ice. No temperature control is performed routinley and therefore lower or…2020 American Transplant Congress
First U.S. DCD Heart Procured/Transplanted after Normothermic Regional Perfusion
*Purpose: We successfully planned, procured and transplanted a heart after a Donation After Cardiac Death (DCD) protocol with post-declaration implementation of in vivo cardiopulmonary bypass…2020 American Transplant Congress
Making History, Saving Lives: One OPOs Experience Making History by Being the First in the Nation to Successfully Allocate Seven Organs for Transplant from a Donation after Circulatory Death (DCD) Donor
LifeShare Transplant Donors Services, Oklahoma City, OK
*Purpose: At the time of this recovery, our OPO’s percentage of DCD donors was 41%. Continuing to maximize the gift successfully by increasing the percentage…2020 American Transplant Congress
Successful Transplantation of Murine Hearts Preserved 24h Under Subzero Ischemia Using Novel Bio-Inspired Next Generation Cryoprotectants
*Purpose: Extension of the organ ischemia window is of paramount importance to prolong viability of transplantable organs and to improve overall outcomes. Transport using a…2020 American Transplant Congress
Ex Vivo Pumping Through an OPO’s Eyes
*Purpose: A single, large organ procurement organization (OPO) sought to document the use of extra-renal ex vivo pumping in the management of the deceased donor…2020 American Transplant Congress
Comparing Two Methods of Minimally-Ischemic Cardiac Preservation in Life-Supporting Cardiac Xenotransplantation Model
*Purpose: Transplantation of organs from animals to humans (xenotransplantation) has been proposed to address the critical shortage of organs for transplantation. The use of genetically…2020 American Transplant Congress
Cardiac Transplantation is Accompanied by Major T and NK Cell Alterations within the First 24 Hours
*Purpose: Allogeneic heart transplantation (HTx) displays the only curative approach for terminal heart insufficiency while acute allograft rejection remains a major complication. However, early kinetics…2020 American Transplant Congress
The Effect of UNOS Donor Policy Change on Ischemic Time and the Effects on Mortality in Heart Transplantation
*Purpose: In light of the recent change in the UNOS allocation policy, we sought to evaluate the impact of ischemic time on mortality.*Methods: Using the…2019 American Transplant Congress
Mitochondrial Permeability Regulates Heart Graft Ischemia – Reperfusion Injury and Rejection
*Purpose: A growing body of evidence indicates that mitochondrial permeability transition pore (mPTP) formation plays a crucial role in necroptosis - a programmed form of…2019 American Transplant Congress
Erk-elk1-mir-711 Signalling In Cardiac Ischemia Reperfusion Injury In Heart Transplantation
Pathology, University of Western Ontario, London, ON, Canada
*Purpose: This study aims to discover new molecular mechanisms involved in and to develop new treatment for preventing ischemia reperfusion injury in heart transplantation.*Methods: The…