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American Transplant Congress abstracts

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Articles tagged "Heart preservation"

  • 2020 American Transplant Congress

    First Experience with a New Storage Device for Cold Heart Preservation

    A. Zuckermann, J. Gökler, P. Kaiser, E. Ceran, N. Neuber, P. Angleitner, G. Laufer, A. Aliabadi-Zuckermann

    Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria

    *Purpose: The standard technology for heart preservation for transplantation is cold static storange on ice. No temperature control is performed routinley and therefore lower or…
  • 2020 American Transplant Congress

    First U.S. DCD Heart Procured/Transplanted after Normothermic Regional Perfusion

    A. L. Friedman1, Z. N. Kon2, D. E. Smith2, B. Sullivan3, J. Carillo2, N. Moazami2

    1LiveOnNY, New York, NY, 2Cardiothoracic Surgery, NYU Langone Transplant Institute, New York, NY, 3NYU Langone Transplant Institute, New York, NY

    *Purpose: We successfully planned, procured and transplanted a heart after a Donation After Cardiac Death (DCD) protocol with post-declaration implementation of in vivo cardiopulmonary bypass…
  • 2020 American Transplant Congress

    Making History, Saving Lives: One OPOs Experience Making History by Being the First in the Nation to Successfully Allocate Seven Organs for Transplant from a Donation after Circulatory Death (DCD) Donor

    J. B. Nave, A. J. Boyer, C. A. Hostetler, C. C. Muse, R. A. Squires, J. P. Orlowski

    LifeShare Transplant Donors Services, Oklahoma City, OK

    *Purpose: At the time of this recovery, our OPO’s percentage of DCD donors was 41%. Continuing to maximize the gift successfully by increasing the percentage…
  • 2020 American Transplant Congress

    Successful Transplantation of Murine Hearts Preserved 24h Under Subzero Ischemia Using Novel Bio-Inspired Next Generation Cryoprotectants

    B. Oh1, A. Callegari2, M. Kline2, A. Childs2, M. Iglesias Lozano1, G. Brandacher1, X. Wei2

    1Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation (VCA), Johns Hopkins University School of Medicine, Baltimore, MD, 2X-Therma Inc., Richmond, CA

    *Purpose: Extension of the organ ischemia window is of paramount importance to prolong viability of transplantable organs and to improve overall outcomes. Transport using a…
  • 2020 American Transplant Congress

    Ex Vivo Pumping Through an OPO’s Eyes

    A. L. Friedman, E. Marquez

    LiveOnNY, New York, NY

    *Purpose: A single, large organ procurement organization (OPO) sought to document the use of extra-renal ex vivo pumping in the management of the deceased donor…
  • 2020 American Transplant Congress

    Comparing Two Methods of Minimally-Ischemic Cardiac Preservation in Life-Supporting Cardiac Xenotransplantation Model

    C. E. Goerlich1, A. Singh1, D. Kaczorowski1, M. Abdullah1, B. Lewis1, I. Tatarov1, A. Hershfeld1, T. Zhang1, E. Strauss1, P. Odonkor1, B. Williams1, D. Ayares2, B. Griffith1, M. Mohiuddin1

    1Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Surgery, Revivicor, Blacksburg, VA

    *Purpose: Transplantation of organs from animals to humans (xenotransplantation) has been proposed to address the critical shortage of organs for transplantation. The use of genetically…
  • 2020 American Transplant Congress

    Cardiac Transplantation is Accompanied by Major T and NK Cell Alterations within the First 24 Hours

    J. Iske1, B. Wiegmann2, K. Ludwig1, N. Ledwoch1, E. Chichelnitskiy1, J. F. Kühne1, A. Hitz1, R. Bellmàs-Sanz1, K. Daemen1, J. Keil1, F. Ius2, S. Rochas2, A. Knoefel2, A. Haverich2, G. Warnecke2, C. S. Falk1

    1Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany, 2Division of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany

    *Purpose: Allogeneic heart transplantation (HTx) displays the only curative approach for terminal heart insufficiency while acute allograft rejection remains a major complication. However, early kinetics…
  • 2020 American Transplant Congress

    The Effect of UNOS Donor Policy Change on Ischemic Time and the Effects on Mortality in Heart Transplantation

    A. Lee1, K. Yang1, G. Liu1, C. Lum2, A. D. Salimbangon3, R. R. Chand4, P. Banankhah1, P. Genyk1, P. Kingsford1, J. Li1, J. Li1, D. Vucicevic5, K. Pandya1, J. Rahman1, M. Fong1, L. Grazette1, A. Kiankhooy1, J. Nattivjonathan.nattiv@med.usc.edu1, S. Hashmi1, A. Gong1, J. Pizula1, D. Miklin1, S. Shah1, A. Vaidya1, A. Wolfson6, E. Depasquale1

    1Keck Medicine of USC, Los Angeles, CA, 2The Queens Medical Center, Honolulu, HI, 3UCLA Medical Center, Los Angeles, CA, 4Harbor-UCLA Medical Center, Los Angeles, CA, 5Newark Beth-Israel Medical Center, Newark, NJ, 6University of Arizona Sarver Heart Center, Tuscon, AZ

    *Purpose: In light of the recent change in the UNOS allocation policy, we sought to evaluate the impact of ischemic time on mortality.*Methods: Using the…
  • 2019 American Transplant Congress

    Mitochondrial Permeability Regulates Heart Graft Ischemia – Reperfusion Injury and Rejection

    A. Qamar1, J. Jiang1, X. Huang2, P. McLeod2, A. M. Jevnikar2, Z. Zhang2

    1Pathology and Laboratory Medicine, University of Western Ontario, London, ON, Canada, 2London Health Sciences Centre, London, ON, Canada

    *Purpose: A growing body of evidence indicates that mitochondrial permeability transition pore (mPTP) formation plays a crucial role in necroptosis - a programmed form of…
  • 2019 American Transplant Congress

    Erk-elk1-mir-711 Signalling In Cardiac Ischemia Reperfusion Injury In Heart Transplantation

    H. Zheng, Y. Su, C. Zhu, V. Veramkovich, X. Zheng

    Pathology, University of Western Ontario, London, ON, Canada

    *Purpose: This study aims to discover new molecular mechanisms involved in and to develop new treatment for preventing ischemia reperfusion injury in heart transplantation.*Methods: The…
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