2016 American Transplant Congress
Evolving to Everolimus: A Safe and Effective Option for Pancreas Transplant.
University of Utah Health Care, Salt Lake City, UT.
Although everolimus is an attractive option for conversion therapy in pancreas tx pts that experience SE's of commonly used immunosuppression, TAC and MPA, there is…2016 American Transplant Congress
Refill-Based Immunosuppression Non-Adherence Is Associated with Increased Death Censored Graft Loss.
Medicine, University of Alberta, Edmonton, AB, Canada.
Introduction Medication non-adherence is a major contributor of graft loss in kidney transplant(KTX) recipients. We aim to evaluate the association of immunosuppression non-adherence to graft…2016 American Transplant Congress
Heterologous Persistent and Latent Viral Infections Do Not Impact Graft Survival.
1Duke University, Durham; 2Emory University, Atlanta.
Purpose: Infection induces costimulation-resistant memory T cells with heterologous alloreactivity. Rapamycin has been shown to mitigate the effect of these cells in transplant rejection. Previous…2016 American Transplant Congress
Prolonged Pre-Transplant Dialysis Duration Reverses the “Nephroprotective Effect” in Simultaneous Liver-Kidney Transplant Recipients.
University of Florida, Gainesville.
Past literature has suggested that simultaneous liver-kidney(SLK) transplant recipients may experience a nephroprotective effect compared to kidney(Ki) alone transplant recipients. Since hepatorenal syndrome is a…2016 American Transplant Congress
Clinical Significance of C3d Binding Donor Specific Anti-HLA Antibodies (DSA) Detected by Single Antigen Beads (SAB) After Kidney Transplantation.
A new Luminex-based SAB method detects DSA compliment fixing via C3d-binding. This study compares the clinical outcomes in kidney recipients that developed de novo DSA…2016 American Transplant Congress
The Combined Effect of Acute Rejection and De Novo Donor-Specific Antibodies on Kidney Allograft Survival.
Division of Renal Diseases and Hypertension, University of Colorado, Aurora, CO.
While dnDSA is associated with graft loss in multiple studies, the clinical context in which dnDSA develops and contributes to graft loss is less well…2016 American Transplant Congress
Post-Transplantation Hypomagnesemia as a Predictor of Survival Among the Kidney Transplant Population.
Transplant Research Center, Brigham and women's hospital, Boston, MA.
We have previously shown a robust relationship between low magnesium in the first year post-transplant and better long-term kidney allograft function. Given this somewhat counterintuitive…2016 American Transplant Congress
NAD+ Promotes Allograft Survival Independently of CD4+CD25+Foxp3+ Regulatory T Cells.
CD4+CD25+Foxp3+ regulatory T cells (Tregs) play a central role in the maintenance of immune tolerance and T cell homeostasis. It is known that Tregs promote…2016 American Transplant Congress
Composite Score to Define the Risk of Allograft Loss After Standard-of-Care Treatment of Antibody-Mediated Rejection in Kidney Transplantation.
The development of a reliable surrogate endpoint for allograft survival after AMR treatment is a current unmet need in clinical transplantation (FDA AMR Workshop). We…2016 American Transplant Congress
Detection of Venous Thrombi by Microdialysis Catheters and Angiographic Guided Thrombus Extraction in Two Solitary Pancreas Transplants.
Introduction: The complication rate after pancreas transplantation (PTx) is very high, with venous thrombosis being the most commonly occurring complication that leads to early graft…
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