ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2016 American Transplant Congress

    Role of Induction Therapy in Low Immune Risk Kidney Transplant Recipients.

    B. Chopra, K. Sureshkumar.

    Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA.

    Induction therapy improves outcomes in kidney transplant recipients (KTRs) by reducing early acute rejection. In the current era of potent maintenance immunosuppression, the role of…
  • 2016 American Transplant Congress

    Use of Elderly Donors in Liver Transplantation: A Paired-Match Analysis at a Single Center.

    D. Ghinolfi, Q. Lai, P. DeSimone, D. Pezzati, G. Cirillo, F. Filipponi.

    Liver Surgery and Transplantation, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.

    Introduction: Use of livers from very old donors is a way to expand the donor pool, but this practice is not universally implemented due to…
  • 2016 American Transplant Congress

    Outcome After Kidney Transplant (KTx) in Patients with Chronic Hypotension on Haemodialysis (HD).

    O. Manolitsi, N. Kessaris, J. Olsburgh, I. Loukopoulos.

    Kidney and Pancreas Transplant Unit, Surgical Department, Guy's and St Thomas'NHS Foundation Trust, London, United Kingdom.

    5% of the HD population have chronic hypotension ( hypotension in the absence of volume depletion, antihypertensive medication, heart failure or cortisol deficiency). The perioperative…
  • 2016 American Transplant Congress

    Urinary Virome in Human Kidney Transplants Reveals Multiple Virus Subtypes with Distinct Genome Polymorphisms.

    R. Ranjan,1 A. Rani,1 H. McGee,1 D. Brennan,2 P. Finn,1 D. Perkins.1,3

    1Medicine, University of Illinois, Chicago, IL; 2Division of Renal Diseases, Washington University School of Medicine, St. Louis, MO; 3Surgery, University of Illinois, Chicago, IL.

    Recent studies have established that human urine has its own unique microbiome, but little is known about the virome. The human virome is the collection…
  • 2016 American Transplant Congress

    Fecal Microbiota Transplant Results in Durable Changes to Host Microbiota That Correlate with Allograft Outcome.

    C. Brinkman, L. Hittle, W. Fricke, E. Mongodin, J. Bromberg.

    CVID and IGS, University of Maryland School of Medicine, Baltimore, MD.

    Hypothesis: We previously presented highly significant differences in the bacterial community structures of human renal allograft recipients over time. Likewise, murine normal, colitic, and pregnant…
  • 2016 American Transplant Congress

    Machine Perfusion (MP) at 21[deg]C Simulates Hibernation Metabolic Pathways in a Non-Hibernator Mammal.

    B. Banan, S. Dobrowolski, G. Michalopoulos, P. Fontes.

    University of Pittsburgh, Pittsburgh.

    Background: Hibernation is a complex and multi stage process that leads to unique metabolic changes over an extended period of time. Regulatory genes and transcription…
  • 2016 American Transplant Congress

    Donor-Recipient Absolute Weight Mismatch and the Risk of Graft Loss in Renal Transplantation.

    A. Miller,1 B. Kiberd,1 I. Alwayn,2 K. Tennankore.1

    1Medicine, Division of Nephrology, Dalhousie University, Halifax, NS, Canada; 2Surgery, Multi Organ Transplant Program, Dalhousie University, Halifax, NS, Canada.

    Background: Relatively smaller kidney donor to recipient size is proposed to result in increased graft loss due to nephron underdosing and hyperfiltration injury but few…
  • 2016 American Transplant Congress

    Influence of Pancreas Import and Cold Ischemia on Outcomes Following Pancreas Transplantation.

    M. Khan,1 H. El-Hennawy,1 J. Rogers,1 A. Farney,1 G. Orlando,1 A. Reeves-Daniel,2 A. Palanisamy,2 R. Stratta.1

    1Surgery, Wake Forest, Winston-Salem, NC; 2Internal Medicine, Wake Forest, Winston-Salem, NC.

    Proposed changes in pancreas transplant (PT) allocation may improve organ sharing but increase cold ischemia time (CIT). Methods: We performed a single center, retrospective study…
  • 2016 American Transplant Congress

    Evaluating Delayed Graft Function After Kidney Transplantation as a Potential Surrogate Outcome.

    S. Cramm, X. Luo, A. Massie, D. Segev.

    Department of Surgery, Johns Hopkins, Baltimore, MD.

    Background: Recent work demonstrates significant inter-center heterogeneity in delayed graft function (DGF) rates after kidney transplantation, calling into question the value of a metric based…
  • 2016 American Transplant Congress

    Donor Sharpin Expression Modulates TNFα Mediated Inflammation and Cardiac Allograft Rejection in Mice.

    R. Ang,1 P. Heeger,2 A. Ting.1

    1Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, NY; 2Center for Translational Transplant Research, Icahn School of Medicine at Mount Sinai, New York City, NY.

    Increased systemic TNFα levels correlate with transplant rejection and severity of GVHD, and TNFα blockade can prolong graft survival and reduce severity of GVHD. These…
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