2016 American Transplant Congress
Delayed Graft Function (DGF) Does Not Accelerate Progression of Fibrosis During the First Year After Deceased Donor Kidney Transplantation.
BackgroundOur aim was to study the impact of DGF on the progression of interstitial fibrosis during the first post-transplant year.MethodsWe included all patients who received…2016 American Transplant Congress
Everolimus Decline Anti-ABO Blood Type Antibody Titer in Desensitization for ABO Incompatible Kidney Transplantation.
Kidney Transplantation Surgery, Sapporo City General Hospital, Sapporo, Hokkaido, Japan.
INTRODUCTION: The immoderate donor shortage and sophisticated desensitization protocols resulted in the explosive increase and great success of the ABO blood type incompatible kidney transplantation…2016 American Transplant Congress
The Effect of Spironolactone on Calcineurininhibitor Induced Nephrotoxicity.
Purpose: Evidence points towards activation of the mineralocorticoid receptor (MR) to be involved in CNI nephrotoxicity. The SPIREN trial was designed to test the hypothesis…2016 American Transplant Congress
Belatacept Immunotherapy Is Not Augmented by Blockade of Activated LFA-1 in a Nonhuman Primate Renal Transplant Model.
1Department of Surgery, Duke University Medical Center, Durham, NC; 2Emory University, Atlanta, GA.
Purpose: Belatacept specifically targets de novo alloimmune responses without off target side effects. However, resistant alloreactive memory T cells have complicated its use. LFA-1 therapy…2016 American Transplant Congress
Dual Kidney Transplants as Policy to Optimize the Allocation of Marginal Donor Kidneys: Analysis of the French Cohort Since 2002.
The aim of this national multicentre cohort study was to assess the safety of dual kidney transplantation (DKT) in terms of patient and graft survival…2016 American Transplant Congress
The Use of Kidneys with Acute Kidney Injury: The Good, the Bad and the Ugly.
Introduction:The widening gap between supply and demand in kidney transplantation has lead to the increased use of kidneys from marginal donors, including those with acute…2016 American Transplant Congress
Everolimus Abrogates C5a and TGFβ Mediated Perycite-to-Myofibroblast Transition (PMT) Inhibiting Vascular Rarefaction.
Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Microvascular pericytes have detrimental effects on tubulo-interstitial fibrosis via PMT. However, therapeutic strategies that might interfere with this process are currently lacking. We aimed to…2016 American Transplant Congress
The Treatment of Borderline Lesion in Protocol Biopsies Did Not Improve the Outcome in Kidney Transplant Recipients.
Introduction. Up to 30% of patients with protocol biopsies and stable renal function have borderline lesions. His relationship with acute rejection remains uncertain, as does…2016 American Transplant Congress
Evaluation of a Risk-Stratified Induction Immunosuppression Protocol Utilizing Low-Dose Antithymocyte Globulin in Renal Transplantation.
Lower doses of rabbit-derived antithymocyte globulin (rATG) may result in less infection and cost, but may increase the incidence of acute rejection. We compared the…2016 American Transplant Congress
Criteria for the Diagnosis of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx).
The presence of MVI (Banff glomerulitis "g" score and Banff peritubular capillary "ptc" score) in KTxBx, often related to antibody mediated rejection (AMR), is associated…
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