Articles tagged "Graft survival"

2017 American Transplant Congress
Potential Mechanism Involving Regulatory T Cells in Induction of Tolerance in Mouse Vascularized Composite Allotransplantation Under Combined Costimulation Blockade.
M. Anggelia,^1,2 Y.-Y. Huang,³ W.-Y. Chuang,⁴ H.-Y. Cheng,¹ G. Brandacher,⁵ F.-C. Wei,^1,2 C.-H. Lin.^1,2
¹PRS, Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital, Taoyuan, Taiwan; ²Chang Gung Medical College and Chang Gung University, Taoyuan, Taiwan; ³Nephrology, Chang Gung Memorial Hospital, Taoyuan, Taiwan; ⁴Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan; ⁵Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD
Background: Role of Regulatory T cells in vascularized composite allotransplantation (VCA) remains to be elucidated. In this study, we investigate potential mechanism involved in Tregs…
2017 American Transplant Congress
Ischemia-Reperfusion Injury-Induced Innate Immune Signaling in Human Orthotopic Liver Transplantation.
R. Sosa,¹ A. Zarrinpar,² M. Rossetti,¹ C. Lassman,¹ B. Naini,¹ N. Datta,² R. Busuttil,² D. Gjertson,¹ J. Kupiec-Weglinski,^1,2 E. Reed.¹
¹Pathology and Laboratory Medicine, University of California, Los Angeles, CA; ²Surgery, University of California, Los Angeles, CA
Background: Ischemia-reperfusion injury (IRI) is a major risk factor in the development of acute and chronic graft rejection in orthotopic liver transplantation (OLT); however, no…
2017 American Transplant Congress
Absence of Independent and Additional Predictive Ability of Preimplantation Kidney Allograft Biopsies for Long-Term Outcome: Population Based Study.
O. Aubert, D. Viglietti, C. Loheac, M. Rabant, C. Gosset, J. Duong Van Huyen, D. Glotz, C. Legendre, C. Lefaucheur, A. Loupy.
Paris Translational Research Center for Organ Transplantation, Paris, France
BackgroundA significant number of kidneys are discarded worldwide due to the suboptimal use of large kidney resources. The mean cause is the result of the…
2017 American Transplant Congress
A Comparison of Desensitization Protocols: Rituximab with/without Plasmapheresis in ABO-Incompatible Living Donor Liver Transplantation.
E. Lee, S. Kim, S. Lee, S.-J. Park.
Center for Liver Cancer, National Cancer Center, Goyang, Korea
Background: Plasmapheresis is a desensitization method used prior to ABO-incompatible (ABO-I) living donor liver transplantation (LDLT). However, studies on its usefulness in the rituximab era…
2017 American Transplant Congress
Kidney Allograft Offers: Predictors of Turndown and the Relationship of Organ Acceptance Sequence to Kidney Allograft Survival.
J. Cohen,^1,2 J. Shults,² D. Goldberg,^2,3 D. Sawinski,¹ P. Abt,⁴ P. Reese.^1,2
¹Renal Division, University of Pennsylvania, Philadelphia, PA; ²Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA; ³Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; ⁴Transplant Surgery, University of Pennsylvania, Philadelphia, PA
Background: There is growing interest in understanding patterns of organ acceptance and reducing organ discard. Little is known about how donor factors, holidays, and location…
2017 American Transplant Congress
Outcome of Adult Living Donor Renal Transplants in Different Era: Analysis of UNOS Database.
V. Whittaker, R. Gruessner, M. Laftavi, Z. Acun, A. Gruessner.
Surgery, State University New York, Syracuse, NY
Background:Living donation is the potential solution to increasing donor donor shortage. This retrospective analysis of UNOS database analyses the outcome of living donor transplantation across…
2017 American Transplant Congress
Retrospective Analysis of Kidney Transplant Recipients with Antibody-Mediated Rejection.
G. Piñeiro,¹ E. Desousa,¹ J. Villarreal,¹ M. Lozano,² J. Cid,² M. Sole,³ F. Oppenheimer,¹ F. Diekmann.¹
¹Nephrology and Renal Transplant, Hospital Clinic de Barcelona, Barcelona, Spain; ²Apheresis Unit, Department of Hemotherapy and Hemostasis, Hospital Clinic de Barcelona, Barcelona, Spain; ³Pathology, Hospital Clinic de Barcelona, Barcelona, Spain
Acute antibody mediated rejection (AMR) is a major cause of allograft loss.We retrospectively reviewed all kidney allograft recipients between 2002 and March 2016. Investigated the…
2017 American Transplant Congress
Long-Term Pediatric Live-Donor Liver Transplantation Survivors: Patient and Allograft Outcomes.
N. Celik,¹ A. Ganoza,¹ G. Bond,¹ K. Soltys,¹ R. Sindhi,¹ P. McKiernan,³ A. Humar,² G. Mazariegos.¹
¹Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; ²Thomas E. Starzl Transplantation Institute, Pittsburgh, PA; ³Division of Pediatric Gastroenterology, Pittsburgh, PA
Aim: To determine the patient and allograft outcomes at 5 years after pediatric live-donor liver transplantation (LDLT).Methods: Children with a minimum of 5-year survival post-transplantation…
2017 American Transplant Congress
A Comparative Study of Patient and Graft Qualities Between Abo-Compatible and -Incompatible Recipients More Than Ten Years After Kidney Transplantation.
H. Ishida, T. Shimizu, M. Okumi, K. Unagami, K. Omoto, K. Tanabe.
Urology, Tokyo Women's Medical University, Tokyo, Japan
Background. The long-term benefits of ABO-I kidney transplantation in terms of adverse events due to severe immunosuppression immediately before transplantation remain unclear.Patients and Methods. Between…
2017 American Transplant Congress
Steroid Free Maintenance Immunosupression in Kidney Transplantation: Indiana University Experience.
S. Hussain, T. Taber, A. Sharfuddin, M. Yaqub, W. Goggins, D. Mishler, O. Adebiyi.
Renal Transplant, Indiana University School of Medicine, Indianapolis, IN
Background: Steroid based maintenance Immunosuppression (IS) regimen is the standard protocol for many kidney transplant(tx) centers. However, concerns for chronic steroid impact on patients remains…