ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2017 American Transplant Congress

    Induction of Delayed Renal Allograft Tolerance Using Only Clinically Available Reagents in Non-Human Primates.

    K. Hotta, T. Oura, A. Dehnadi, S. Boskovic, M. Matsunami, I. Rosales, N. Smith, R. Colvin, A. Cosimi, T. Kawai.

    Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA

    Background: We have previously reported successful induction of renal allograft tolerance following a period of conventional immunosuppression (Delayed tolerance) using nonmyeloablative conditioning that included anti-CD154…
  • 2017 American Transplant Congress

    Pregnancy After Kidney-Pancreas Transplantation: Maternal and Offspring Outcomes.

    S. Rao,1 L. Coscia,2 D. Armenti,2 S. Constantinescu,1,2 M. Moritz.2,3,4

    1Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA; 2Gift of Life Institute, Transplant Pregnancy Registry International, Philadelphia, PA; 3Surgery, Lehigh Valley Health Network, Allentown, PA; 4Morsani College of Medicine, USF, Tampa

    This study analyzed 109 pregnancies (116 outcomes) in 62 female kidney-pancreas (KP) recipients reported to the Transplant Pregnancy Registry International (TPR). Data were collected via…
  • 2017 American Transplant Congress

    A Combination of Anti-CD40L-Ab, Rapamycin, and Donor Apoptotic Cells Prolongs Allogeneic Pancreatic Islet Survival in Sensitized Mice by Regulating Memory Responses.

    A. Dangi,1 H.-K. Kang,1 X. Zhang,2,3 X. Luo.1,2,3

    1Nephrology and Hypertension, Northwestern University, Chicago, IL; 2Comprehensive Transplant Center, Northwestern University, Chicago, IL; 3Surgery, Northwestern University, Chicago, IL

    Accelerated rejection of allografts has been a clinical challenge in solid organ transplantation particularly in sensitized recipients with donor-specific antibodies (DSA) and memory cell repertoires.…
  • 2017 American Transplant Congress

    Presence of Complement Activating Donor Specific Antibodies Is Associated with Poor Renal Allograft Survival: Two Centre Retrospective Study.

    A. Babu,1,4,5 O. Shaw,2 L. Howe,2 N. Kessaris,3 A. Dorling,3 N. Mamode,3 R. Vaughan,2 N. Krishnan,5 R. Higgins,5 D. MItchell,1 D. Briggs,4 S. Daga.1,5,6

    1Warwick Medical School, University of Warwick, Coventry, United Kingdom; 2Clinical Transplantation Laboratories, Guy's Hospital, Viapath, London, United Kingdom; 3Nephrology and Transplantation, Guy's Hospital, London, United Kingdom; 4Histocompatibility and Immunogenetics, NHS Blood and Transfusion, Birmingham, United Kingdom; 5Nephrology and Transplantation, University Hospitals Coventry and Warwickshire, Coventry, United Kingdom; 6Nephrology and Transplantation, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Introduction: Complement fixing donor specific antibodies (DSA) as detected by presence of C3d at the time of rejection is associated with poor graft outcome;no studies…
  • 2017 American Transplant Congress

    Post Transplant Outcomes in Hepatitis C Positive Patients.

    M. Lubetzky, N. Hayde, L. Kamal, M. Ajaimy, P. Bedi, G. Deboccardo, J. Rocca, S. Greenstein, J. Graham, A. Chokechanachaisakul, A. Courson, M. Kinkhabwala, E. Akalin.

    Montefiore Medical Center, Bronx

    Hepatitis C (HCV) is associated with increased morbidity and mortality after kidney transplant (KTx). We aimed to assess outcomes of HCV positive patients at our…
  • 2017 American Transplant Congress

    Vascularized Bone Marrow Mechanisms of Immunomodulation.

    A. Khalifeh, E. Buckingham, M. Uluer, W. Hassanein, W. Twaddell, C. Drachenberg, A. Nam, S. Bartlett, R. Barth.

    University of Maryland School of Medicine, Baltimore, MD

    Introduction:Hand and face transplants containing co-transplanted bone may have improved outcomes. We have previously utilized a NHP model to demonstrate that VCA containing VBM have…
  • 2017 American Transplant Congress

    De-Novo Portal Vein Thrombosis After Adult-to-Adult Living Donor Liver Transplantation (LDLT) Does Not Impact on Long-Term Outcome.

    I. Linares,1 N. Goldaracena,1 R. Rosales,1 L. De La Maza,1 J. Echeverri,1 M. Kaths,1 D. Kollman,1 N. Selzner,2 S. McCluskey,3 G. Sapisochin,1 L. Lilly,2 P. Greig,1 M. Bhat,2 A. Ghanekar,1 M. Cattral,1 I. McGilvray,1 D. Grant,1 M. Selzner.1

    1Department of Surgery, Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada; 2Department of Medicine, Multi-Organ Transplant Program, Toronto General Hospital University Health Network, Toronto, ON, Canada; 3Department of Anesthesiology, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    Portal vein thrombosis(PVT) after deceased donation has been widely described as a liver transplant complication that can lead to graft failure, high morbidity and mortality.…
  • 2017 American Transplant Congress

    Differences in Racial and Sex Disparities in Liver Transplantation Outcomes Between Older and Younger Adult Recipients.

    Q. Huang, C. Haugen, X. Luo, A. Massie, M. McAdams-DeMarco, D. Segev.

    Johns Hopkins University, Baltimore

    Background: More older adults underwent liver transplantation (LT) in the past decade. While racial and sex disparities in LT outcomes have been reported in general,…
  • 2017 American Transplant Congress

    Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome Appearance After Lung Transplantation.

    R. Danger,1 P. Royer,2 D. Reboulleau,2 J. Loy,2 A. Tissot,2 P. Lacoste,2 A. Roux,3 M. Reynaud-Gaubert,4 R. Kessler,5 S. Mussot,6 C. Dromer,7 O. Brugière,8 J. Mornex,9 R. Guillemain,10 M. Dahan,11 C. Knoop,12 K. Botturi,2 C. Pison,13 L. Nicod,14 S. Brouard,1 A. Magnan,2 COLT and SysCLAD Consortia.

    1CRTI UMR1064, INSERM, Université de Nantes, ITUN, CHU Nantes, Nantes, France; 2UMR_S 1087 CNRS UMR_6291, Institut du Thorax, Université de Nantes, CHU de Nantes, Nantes, France; 3CHU de Marseille, Aix Marseille Université, Marseille, France; 4CHU de Strasbourg, Strasbourg, France; 5Service de Chirurgie Thoracique, Vasculaire et Transplantation Cardiopulmonaire, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France; 6CHU de Bordeaux, Bordeaux, France; 7Service de Pneumologie et Transplantation Pulmonaire, Hôpital Bichat, Paris, France; 8Université de Lyon, INRA, UMR754, Lyon, Hospices Civils de Lyon, Lyon, France; 9Hôpital Européen George Pompidou, Paris, France; 10CHU de Toulouse, Toulouse, France; 11Hôpital Erasme, Bruxelles, Belgium; 12Clinique Universitaire Pneumologie, Pôle Thorax et Vaisseaux, CHU de Grenoble, Université de Grenoble, Inserm U1055, Grenoble, France; 13Service de Pneumologie, Centre de Transplantation, Lausanne, Switzerland

    Bronchiolitis obliterans syndrome (BOS) is the main manifestation of chronic lung allograft dysfunction responsible for the poor long-term outcome after lung transplantation. While physiopathological mechanisms…
  • 2017 American Transplant Congress

    An Argument for Expanding the Simultaneous Liver and Kidney Transplant Criteria: Validity of the New UNOS Allocation Policy.

    S. Nagai,1 M. Safwan,1 K. Collins,1 M. Rizzari,1 D. Moonka,2 K. Brown,2 A. Patel,3 A. Yoshida,1 M. Abouljuod.1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 2Gastroenterology, Henry Ford Hospital, Detroit, MI; 3Nephrology, Henry Ford Hospital, Detroit, MI

    Aim: According to the latest simultaneous liver-kidney transplant (SLK) allocation policy by UNOS, allocation of kidney is dependent on duration of low glomerular filtration rate…
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