2017 American Transplant Congress
Differential Effects of the Novel ATP-Competitive mTOR Inhibitor (TORKinib) AZD2014 and Rapamycin on Alloimmunity and Transplant Survival.
Surgery, Thomas Starzl Transplantation Institute, Pittsburgh, PA
Background: Rapamycin (RAPA), is an immunosuppressive agent that inhibits the mechanistic target of Rapamycin (mTOR), the kinase subunit of two mTOR- containing complexes (mTORC1 and…2017 American Transplant Congress
Improved Outcome of Kidney Transplants by Donor Recipient Matching Based on Predicted Indirectly Recognizable HLA Epitopes.
Introduction: De novo donor-specific HLA antibodies (dnDSA) are recognized as a risk factor for graft loss. Determinants of DSA specificity are generated via the indirect…2017 American Transplant Congress
Not All Cellular Rejections Are the Same: Differences in Early and Late Hepatic Allograft Rejection.
While acute cellular rejection (ACR) after liver transplantation (LT) is not thought to cause long-term graft injury and inferior outcomes, this notion has been challenged…2017 American Transplant Congress
Variations in Risk-Appetite Between UK Kidney Transplant Centres and Impact on Patient and Graft Outcomes.
Introduction: Risks associated with deceased donors may be donor-related, organ-related, or both. Variations between transplant centres in the risks they are prepared to accept ('risk…2017 American Transplant Congress
Poor Outcome of Polyomavirus -Associated Nephropathy with Glomerular Parietal Epithelial Cells Infected by Polyomavirus.
Background: Bowman's capsular epithelium infected by polyomavirus(Py) in polyomavirus -associated nephropathy (PyVAN) is infrequent and considered as the advanced stage of the disease. The aim…2017 American Transplant Congress
C1q+ and IgG3+ De Novo Donor Specific Antibody Are Associated with Allograft Failure in a Multicenter Cohort.
Introduction: De novo donor specific antibody (dnDSA) is a risk factor for antibody mediated rejection and allograft loss, but dnDSA does not always lead to…2017 American Transplant Congress
Liver Transplantation for Adolescents with Biliary Atresia in the PELD/MELD Era: An Analysis of the UNOS Database.
While poor bile drainage after a Kasai hepatoportoenterostomy (KPE) is the primary driver for liver transplantation (LT) for Biliary Atresia (BA) in infancy, the data…2017 American Transplant Congress
Kidney Transplantation in Octogenarians: The Mayo Clinic Experience.
Transplant Center, Mayo Clinic, Rochester, MN
BackgroundKidney transplantation (KTx) is the preferred renal replacement therapy in selected individuals.There is limited data on transplantation of octogenarians. The purpose of this study was…2017 American Transplant Congress
Steroid Withdrawal Using Everolimus in Maintenance Kidney Transplant Recipients with Post-Transplant Diabetes Mellitus.
Background: Although steroid withdrawal from conventional immunosuppressive therapy has been attempted to ameliorate various complications, especially diabetes mellitus (DM), in kidney transplant recipients, a steroid-sparing…2017 American Transplant Congress
Long-Term Clinical Outcomes of Kidney Transplant Recipients with Body-Size Mismatch Between Recipient and Donor.
[Purpose]In living-donor kidney transplantation between large recipient and small donor, there are concerns of lower graft function and poor graft survival. Thus, we aimed to…
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