ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2017 American Transplant Congress

    Comparing Renal Function Recovery and Long Term Outcomes in Recipients of Standard and Expanded Criteria Donor Kidney Transplants.

    S. Sandal, M. Cantarovich, S. Paraskevas, N. Almaghrawi, P. Chaudhury, J. Tchervenkov.

    McGill University Health Center, Montreal, Canada

    Several donor and recipient characteristics are associated with adverse kidney transplantation (KT) outcomes. Our group has previously shown that based on the donor's terminal creatinine,…
  • 2017 American Transplant Congress

    Anti-Angiotensin Type 1 Receptor Antibodies Associate with Rejection in Simultaneous Pancreas and Kidney Transplant and Pancreas Transplant Alone Recipients.

    A. Peng, D. Dafoe, J. Choi, A. Vo, X. Zhang, R. Najjar, E. Huang, S. Jordan.

    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA

    Background: Anti-angiotensin type 1 receptor antibodies (AT1R Ab) have been found to have a strong association with antibody mediated rejection (Reinsmoen et al, Transpl 2010;…
  • 2017 American Transplant Congress

    Impact of Type of Recipient Diabetes on 1 and 3-Year Kidney Allograft and Patient Outcomes.

    S. Kim, F. Wu, D. Cibrik, Y. Li, A. Naik.

    University of Michigan, Ann Arbor

    The pathophysiology of type 1 (T1DM) and type 2 (T2DM) diabetes is different and has been conjectured to impact transplantation outcomes differently over time especially…
  • 2017 American Transplant Congress

    Results of Biliary Reconstruction with PTFE Graft in Liver Transplantation.

    E. Ayvazoglu Soy,1 G. Moray,1 A. Torgay,2 H. Ozdemir,3 M. Haberal.1

    1General Surgery and Transplantation, Baskent University, Ankara, Turkey; 2Anesthesiology, Baskent University, Ankara, Turkey; 3Pathology, Baskent University, Ankara, Turkey

    Introduction: Biliary complications are often referred to as the 'Achilles heel' of liver transplantation (LT) with their high incidence rate, the need for repeated and…
  • 2017 American Transplant Congress

    Inflammasome, Unfolded Protein Response, and T Cell Immunity in DAIH.

    A. Arterbery,1 M. Martinez,3 S. Lobritto,3 Y. Avitzur,2 U. Ekong.1

    1Ped Gastro. and Hep., Yale University, New Haven, CT; 2Gastro., Hep., and Nutr., Hospital for Sick Children, Toronto, ON, Canada; 3Ped. Gastro., Hep., and Nutr., Columbia University, New York, NY

    Background: Regulatory T cells (Tregs) of patients with de novo autoimmune hepatitis (DAIH) secrete IL-17A & IFN-g; display TH1 & TH17 pehnotypes & are functionally…
  • 2017 American Transplant Congress

    Short- and Long-Term Graft Survival After Kidney Transplantation in Western Europe.

    M. Coemans,1 G. Verbeke, D. Anglicheau, O. Bestard, M. Giral, M. Naesens.1,2

    1Microbiology and Immunology, KU Leuven, Leuven, Belgium; 2Nephrology and Renal Transplantation, KU Leuven, Leuven, Belgium

    Background: Improvement of kidney survival after transplantation has mainly been studied in the American population. There, it was found that improvement mostly occurred on the…
  • 2017 American Transplant Congress

    Deleting LAG-3 Accelerates Cardiac Allograft Rejection and Augments T Cell Memory in Mice.

    J. Erfe,1,2 C. Yang,1 D. Ndishabandi,1 I. Rosales,1 R. White,1 P. Russell,1 R. Colvin,1 J. Madsen,1 A. Alessandrini.1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA; 2Yale School of Medicine, New Haven, CT

    Purpose: Lymphocyte Activation Gene-3 (LAG-3) expresses a transmembrane receptor on activated immune cells such as T cells, NK cells, and plasmacytoid dendritic cells. It is…
  • 2017 American Transplant Congress

    Renal Transplant Outcomes in Primary FSGS Compared with Other Recipients: A National Review of the Irish Transplant Registry.

    S. Cormican,1 C. Kennedy,1,2 P. O'Kelly,1 B. Doyle,3 A. Dorman,3 P. Conlon.1,2

    1Nephrology, Beaumont Hospital, Dublin, Ireland; 2Medicine, Royal College of Surgeons, Dublin, Ireland; 3Pathology, Beaumont Hospital, Dublin, Ireland

    Primary focal segmental glomerular sclerosis (p-FSGS) raises specific peri-transplant concerns, one of which is disease recurrence (r-FSGS). We aimed to compare transplant outcomes in patients…
  • 2017 American Transplant Congress

    Correlation of Complement Activating Donor Specific Antibodies as Measured by C3d and Cross-Match Status.

    A. Babu,1,2,3 N. Krishnan,2 D. Briggs,3 D. Mitchell,1 S. Daga.1,2,4

    1Warwick Medical School, University of Warwick, Coventry, United Kingdom; 2Nephrology and Transplantation, University Hospitals Coventrya and Warwickshire, Coventry, United Kingdom; 3Histocompatibility and Immunogenetics, NHS Blood and Transfusion, Birmingham, United Kingdom; 4Nephrology and Transplantation, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Introduction. Complement dependent cytotoxicity, first described in 1969 is the only functional assay studying complement activation. C3d assay is developed recently to study complement activation…
  • 2017 American Transplant Congress

    Beta Cell-Specific Free Circulating DNA May Predict the Outcome After Clinical Islet Transplantation.

    B. Gala-Lopez,1 D. Neiman,2 T. Kin,1 D. O'Gorman,1 A. Pepper,1 A. Malcolm,1 B. Glaser,3 R. Shemer,2 Y. Dor,2 J. Shapiro.1

    1Department of Surgery, Clinical Islet Transplant Program, University of Alberta, Edmonton, AB, Canada; 2Department of Developmental Biology and Cancer Research, The Hebrew University-Hadassah Medical School, Jerusalem, Israel; 3Endocrinology and Metabolism Service, Department of Internal Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

    Optimizing engraftment and early survival of human beta cells after clinical islet transplantation is critical to long-term function, but there are no reliable, quantifiable measures…
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