Articles tagged "Graft survival"

2017 American Transplant Congress
Post Transplant Outcomes in Hepatitis C Positive Patients.
M. Lubetzky, N. Hayde, L. Kamal, M. Ajaimy, P. Bedi, G. Deboccardo, J. Rocca, S. Greenstein, J. Graham, A. Chokechanachaisakul, A. Courson, M. Kinkhabwala, E. Akalin.
Montefiore Medical Center, Bronx
Hepatitis C (HCV) is associated with increased morbidity and mortality after kidney transplant (KTx). We aimed to assess outcomes of HCV positive patients at our…
2017 American Transplant Congress
Vascularized Bone Marrow Mechanisms of Immunomodulation.
A. Khalifeh, E. Buckingham, M. Uluer, W. Hassanein, W. Twaddell, C. Drachenberg, A. Nam, S. Bartlett, R. Barth.
University of Maryland School of Medicine, Baltimore, MD
Introduction:Hand and face transplants containing co-transplanted bone may have improved outcomes. We have previously utilized a NHP model to demonstrate that VCA containing VBM have…
2017 American Transplant Congress
De-Novo Portal Vein Thrombosis After Adult-to-Adult Living Donor Liver Transplantation (LDLT) Does Not Impact on Long-Term Outcome.
I. Linares,¹ N. Goldaracena,¹ R. Rosales,¹ L. De La Maza,¹ J. Echeverri,¹ M. Kaths,¹ D. Kollman,¹ N. Selzner,² S. McCluskey,³ G. Sapisochin,¹ L. Lilly,² P. Greig,¹ M. Bhat,² A. Ghanekar,¹ M. Cattral,¹ I. McGilvray,¹ D. Grant,¹ M. Selzner.¹
¹Department of Surgery, Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada; ²Department of Medicine, Multi-Organ Transplant Program, Toronto General Hospital University Health Network, Toronto, ON, Canada; ³Department of Anesthesiology, Toronto General Hospital, University Health Network, Toronto, ON, Canada
Portal vein thrombosis(PVT) after deceased donation has been widely described as a liver transplant complication that can lead to graft failure, high morbidity and mortality.…
2017 American Transplant Congress
Differences in Racial and Sex Disparities in Liver Transplantation Outcomes Between Older and Younger Adult Recipients.
Q. Huang, C. Haugen, X. Luo, A. Massie, M. McAdams-DeMarco, D. Segev.
Johns Hopkins University, Baltimore
Background: More older adults underwent liver transplantation (LT) in the past decade. While racial and sex disparities in LT outcomes have been reported in general,…
2017 American Transplant Congress
Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome Appearance After Lung Transplantation.
R. Danger,¹ P. Royer,² D. Reboulleau,² J. Loy,² A. Tissot,² P. Lacoste,² A. Roux,³ M. Reynaud-Gaubert,⁴ R. Kessler,⁵ S. Mussot,⁶ C. Dromer,⁷ O. Brugière,⁸ J. Mornex,⁹ R. Guillemain,¹⁰ M. Dahan,¹¹ C. Knoop,¹² K. Botturi,² C. Pison,¹³ L. Nicod,¹⁴ S. Brouard,¹ A. Magnan,² COLT and SysCLAD Consortia.
¹CRTI UMR1064, INSERM, Université de Nantes, ITUN, CHU Nantes, Nantes, France; ²UMR_S 1087 CNRS UMR_6291, Institut du Thorax, Université de Nantes, CHU de Nantes, Nantes, France; ³CHU de Marseille, Aix Marseille Université, Marseille, France; ⁴CHU de Strasbourg, Strasbourg, France; ⁵Service de Chirurgie Thoracique, Vasculaire et Transplantation Cardiopulmonaire, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France; ⁶CHU de Bordeaux, Bordeaux, France; ⁷Service de Pneumologie et Transplantation Pulmonaire, Hôpital Bichat, Paris, France; ⁸Université de Lyon, INRA, UMR754, Lyon, Hospices Civils de Lyon, Lyon, France; ⁹Hôpital Européen George Pompidou, Paris, France; ¹⁰CHU de Toulouse, Toulouse, France; ¹¹Hôpital Erasme, Bruxelles, Belgium; ¹²Clinique Universitaire Pneumologie, Pôle Thorax et Vaisseaux, CHU de Grenoble, Université de Grenoble, Inserm U1055, Grenoble, France; ¹³Service de Pneumologie, Centre de Transplantation, Lausanne, Switzerland
Bronchiolitis obliterans syndrome (BOS) is the main manifestation of chronic lung allograft dysfunction responsible for the poor long-term outcome after lung transplantation. While physiopathological mechanisms…
2017 American Transplant Congress
An Argument for Expanding the Simultaneous Liver and Kidney Transplant Criteria: Validity of the New UNOS Allocation Policy.
S. Nagai,¹ M. Safwan,¹ K. Collins,¹ M. Rizzari,¹ D. Moonka,² K. Brown,² A. Patel,³ A. Yoshida,¹ M. Abouljuod.¹
¹Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; ²Gastroenterology, Henry Ford Hospital, Detroit, MI; ³Nephrology, Henry Ford Hospital, Detroit, MI
Aim: According to the latest simultaneous liver-kidney transplant (SLK) allocation policy by UNOS, allocation of kidney is dependent on duration of low glomerular filtration rate…
2017 American Transplant Congress
Long-Term Outcome of Antibody-Mediated Rejection Due to Pre-Existing vs. De Novo DSA in Kidney Allograft Recipients.
O. Aubert,¹ C. Lefaucheur,¹ S. Higgins,¹ L. Hidalgo,² J. Duong Van Huyen,¹ D. Viglietti,¹ X. Jouven,¹ D. Glotz,¹ P. Halloran,² A. Loupy.¹
¹Paris Translational Research Center for Organ Transplantation, Paris, France; ²ATAGC, Edmonton, Canada
BackgroundAntibody-mediated rejection (ABMR) can occur in patients with pre-existing anti-HLA donor-specific antibodies (DSA) or in patients who develop de novo DSA. However, how these processes…
2017 American Transplant Congress
Kidney Injury Molecule-1 Mitigates Tissue Damage from Transplant Renal Ischemia Reperfusion Injury.
J. Lee,^1,2 X. Zhang,² A. Haig,³ D. Lian,² P. Anderson,² R. Navaratnam,² L. Gunaratnam.^1,2
¹Department of Microbiology and Immunology, Western University, London, ON, Canada; ²Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; ³Department of Pathology, Western University, London, ON, Canada
Ischemia reperfusion injury (IRI) at the time of organ harvesting is unavoidable, may cause delayed renal graft function, and is associated with premature graft loss.…
2017 American Transplant Congress
Benefits of Induction in Recipients of Acute Renal Failure Donor Kidneys.
M. Barrett, A. Smith, K. Woodside, R. Sung.
University of Michigan, Ann Arbor
Kidneys from donors with acute renal failure (ARF) are often discarded due to concerns for DGF and graft failure. Induction immunosuppression can be used to…
2017 American Transplant Congress
Belatacept Conversion in Kidney Recipients with Low GFR Does Not Improve Renal Function.
D. Abdelwahab,¹ S. Byron,² B. Kaplan,¹ R. Heilman.¹
¹Transplant, Mayo Clinic, Scottsdale, AZ; ²Biostatistics and Informatics, Mayo Clinic, Rochester, MN
Background:Belatacept interferes with signal 2 of T cell activation via blockade CD80/86 which doesn't adversely impact renal function. We tested a hypothesis that Belatacept conversion…