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American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2017 American Transplant Congress

    Donor Warm Ischemic Time >80min Is an Important Predictor of Kidney Graft Survival from Donors After Cardiac Death.

    J. Chen,1 D. Mikhail,2 H. Sharma,3 A. Hijazi,1 D. Nap,1 L. Stitt,4 J. Jevnikar,5 M. Cooper,6 P. Luke,2 A. Sener.2

    1Schulich School of Medicine & Dentistry, London, Canada; 2Urology, Western University, London, Canada; 3General Surgery, Western University, London, Canada; 4LW Stitt Statistical Services, London, Canada; 5Engineering, Ryerson University, Toronto, Canada; 6Georgetown University, Washington

    We analyzed UNOS data to determine how donor warm ischemic time (WIT), donor BMI, donor hypertension (dHTN), cold ischemic time (CIT), and vasopressin use in…
  • 2017 American Transplant Congress

    Gut Microbial Metabolite Improves Function and Prolongs Kidney Allograft Survival in Mice.

    H. Wu,1,2 T. Kwan,1 Y. Loh,1 X. Chen,1 L. Macia,2,3 S. Alexander,2,4 S. Chadban.1,2

    1Kidney Node Laboratory, The Charles Perkins Centre and Renal Medicine, Sydney Medical School and Royal Prince Alfred Hospital, Sydney, Australia; 2University of Sydney, Sydney, Australia; 3Nutritional Immunometabolism Lab, The Charles Perkins Centre, Sydney Medical School, Sydney, Australia; 4Nephrology Department, The Children Hospital at Westmead, Sydney, Australia

    To determine the impact of dietary administration of the gut microbial metabolite sodium acetate (SA) on kidney rejection and survival in a fully MHC-mismatched murine…
  • 2017 American Transplant Congress

    Costimulation Independent Acute Rejection Requires CD127 Signaling.

    D. Mathews, Y. Dong, S. Kim, C. Breeden, A. Adams.

    Department of Surgery, Emory University, Atlanta, GA

    Clinical costimulation blockade with belatacept leads to improved survival and graft function. However, a subset of patients experience costimulation independent rejection. We identified a critical…
  • 2017 American Transplant Congress

    Outcomes of Kidney Transplantation Using Deceased Diabetic Donors.

    F. Khan,1 W. Suki,1 D. Nguyen,2 E. Graviss.2

    1Department of Nephrology, Houston Methodist Hospital, Houston, TX; 2Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX

    Introduction: Histological reversal of diabetic lesions in transplanted kidney once euglycemia has been restored is well documented. Conversely, it is known that diabetes status in…
  • 2017 American Transplant Congress

    Living Kidney Transplant: The Influence of Intraoperative Hemodynamics on Delayed Graft Function.

    R. Schutt,1 J. Case,1 B. Barrick,1 A. Toll,2 C. Marsh.1

    1Scripps Center for Organ and Cell Transplantation, Scripps Green Hospital, La Jolla, CA; 2Research Department and Analytics, UNOS, Richmond, VA

    Despite advantages of living donor kidneys, intraoperative insults may subject these kidneys to poor outcomes. Therefore, we investigated whether intraoperative fluid volumes and hemodynamics in…
  • 2017 American Transplant Congress

    Early Failure of Kidney Transplants in the Current Era.

    I. Helanterä, M. Lempinen.

    Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland

    A. Purpose: The short-term outcome after kidney transplantation has improved substantially, and immunological complications rarely lead to early graft loss. However, a small proportion of…
  • 2017 American Transplant Congress

    Lack of Xenograft Recipient Monitoring by Telemetry Lets Infection Go Unchecked and Trigger Coagulopathy.

    M. Mohiuddin,1 A. Singh,1 J. Chan,1 P. Corcoran,1 B. Lewis,2 M. Thomas,2 D. Ayares,3 K. Horvath.1

    1NHLBI / NIH, Bethesda; 2ORS / NIH, Bethesda; 3Revivicor, Inc, Blackburgh

    Introduction: A major complication of a xenograft is the potential for coagulation disorder characterized by thrombocytopenia and bleeding. This complication was rarely seen in our…
  • 2017 American Transplant Congress

    Outcomes of Moderately to Severely Steatotic Grafts in Liver Transplantation: A Meta-Analysis.

    K. Bonner,1 C. Thongprayoon,2 W. Cheungpasitporn,1 M. Leise.1

    1Mayo Clinic, Rochester; 2Bassett Medical Center, Cooperstown

    Background/Objectives:There is a worldwide need to expand the pool of available liver grafts. Livers with >50% steatosis are discarded for orthotopic liver transplantation (OLT) by…
  • 2017 American Transplant Congress

    Detection of Right Ventricular Dilation and Dysfunction by Transthoracic Echocardiography Predicts Renal Transplant Outcomes.

    F. Tinney Jr,1 S. Lazar,2 A. Naik,2 M. Samaniego-Picota,2 N. Bhave.2

    1Wayne State University School of Medicine, Detroit, MI; 2University of Michigan, Ann Arbor, MI

    Introduction: The prevalence of pulmonary hypertension (PHTN) among end stage renal disease (ESRD) patients on hemodialysis is approximately 40-50%. Right heart catheterization is the gold…
  • 2017 American Transplant Congress

    Effect of AKI Donor Admit Creatinine on Renal Transplant Outcomes.

    E. Giorgakis,1 R. Heilman,2 H. Khamash,2 B. Kaplan,2 A. Moss,1 M. Smith,3 K. Reddy.1

    1Department of Surgery, Mayo Clinic, Phoenix, AZ; 2Department of Medicine, Mayo Clinic, Phoenix, AZ; 3Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ

    Purpose of the study was to explore the effect of admit AKI donor creatinine on graft outcomes.Method: Single center retrospective analysis of kidney transplants performed…
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