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Articles tagged "Graft survival"

  • 2022 American Transplant Congress

    Cold Ischemia Time is More Critical for Older Donor Kidney Survival: A Machine Learning Approach

    J. Kim, J. Ahn, A. Massie, D. Segev, S. Bae

    Johns Hopkins, Baltimore, MD

    *Purpose: Increasing utilization of kidneys from older donors is a potential solution to mitigate the organ shortage. However, older donor age is a risk factor…
  • 2022 American Transplant Congress

    Utility of Urinary CTGF as a Biomarker of Progressive Allograft Dysfunction in Pediatric Renal Transplant Recipients

    L. Sheward1, J. Wedel1, N. Rodig1, A. Kho1, T. Blydt-Hansen2, R. B. Mannon3, D. M. Briscoe1

    1Boston Children's Hospital, Boston, MA, 2BC Children's Hospital, Vancouver, BC, Canada, 3University of Nebraska Medical Center, Omaha, NE

    *Purpose: Previous reports from a number of studies indicate that renal allograft recipients who have inflammatory infiltrates within areas of interstitial fibrosis with tubular atrophy…
  • 2022 American Transplant Congress

    Recipient MCPggaac Haplotype is Associated with Poor Graft Survival in Recipients with De Novo Thrombotic Microangiopathy

    V. Petr1, D. Csuka2, P. Hruba3, Á. Szilágyi2, Z. Prohászka2, O. Viklicky1

    1Dept. of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 2Dept. of Medicine and Hematology, Semmelweis University, Budapest, Hungary, 3Transplant Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

    *Purpose: De novo thrombotic microangiopathy (TMA) is associated with poor kidney graft survival. We aimed to assess the role of common complement haplotypes in kidney…
  • 2022 American Transplant Congress

    Study Of Matrix Metalloproteinases(MMP) And Tissue Inhibitors Of Metalloproteinases(TIMP) In Renal Transplant Recipients(RTR)- Rejectors Versus Stable Graft

    J. P. Tom1, R. Dhital2, A. Sharma3, R. Aggarwal1, R. Nada4, R. Ramachandran5, S. Anand1, M. Minz6, R. Minz1

    1Department of Immunopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India, 2Vaccines and Immunity, Nationwide Children's Hospital, Columbus, OH, 3Department of Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India, 4Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India, 5Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India, 6Department of Renal Transplant Surgery, Fortis Hospital, Mohali, Mohali, India

    *Purpose: Our study aimed to shed light on the role of serum levels of MMP and their inhibitors- TIMP in renal allograft rejection.*Methods: This was…
  • 2022 American Transplant Congress

    Temporal Changes in the Peripheral Immune Profile of Acute Rejection Highlight New Mechanisms of Alloimmunity and Potential Non-Invasive Biomarkers of Rejection in Pediatric Liver Transplantation

    D. N. Sarode1, B. Rocque1, A. Barbetta1, P. Singh1, C. Goldbeck1, C. Weaver2, O. Akbari1, R. Kohli2, J. Emamaullee1

    1University of Southern California Keck School of Medicine, Los Angeles, CA, 2Children's Hospital Los Angeles, Los Angeles, CA

    *Purpose: Acute rejection (AR) is common in pediatric liver transplantation (LT) and can impact late graft loss. Immune subpopulations mediating AR in LT have not…
  • 2022 American Transplant Congress

    Donor Macrophage Depletion Improves Kidney Graft Function Despite Long Cold Ischemia

    C. Jordan1, A. Dangi2, X. Luo1

    1Duke University School of Medicine, Durham, NC, 2Medicine, Duke University, Durham, NC

    *Purpose: Prolonged cold ischemia is a known risk factor for delayed graft function and poorer outcomes after kidney transplantation. Overcoming this obstacle is key to…
  • 2022 American Transplant Congress

    Possible Recurrence Must Not Limit Kidney Transplantations for Patients with Focal Segmental Glomerulosclerosis

    A. Angeletti, M. Gentile, G. Ghiggeri, M. Bruschi, F. Lugani, G. Caridi

    Istituto Giannina Gaslini, Genova, Italy

    *Purpose: Non-genetic forms of Focal Segmental Glomerulosclerosis (FSGS) are at high risk of recurrence after kidney transplant (KT) (55%), when compared to inherited forms (0-4%)…
  • 2022 American Transplant Congress

    Comparison of Outcomes and Management of COVID Infection Among Kidney Transplant Recipients Between Pre-Vaccination Rollout Era and Post-Vaccination Rollout Era

    G. Uehara1, K. Soliman2, V. Rao2, M. Casey2, D. Taber3, M. Posadas Salas2

    1Medical University of South Carolina, Charleston, SC, 2Nephrology, Medical University of South Carolina, Charleston, SC, 3Transplant Surgery, Medical University of South Carolina, Charleston, SC

    *Purpose: The COVID pandemic has posed a significant challenge among kidney transplant recipients (KTR) due to their immunocompromised states. The effects of COVID vaccination on…
  • 2022 American Transplant Congress

    Impact of Donor-to-Recipient Body Surface Area Ratio on Graft Survival and Mortality Following Deceased Donor Liver Transplants

    S. Radomski, L. Zeiser, A. Massie, S. Ottmann, D. Segev, E. King

    Surgery, Johns Hopkins University, Baltimore, MD

    *Purpose: The impact of size mismatch on graft survival in living donor liver transplant is well established but is not a common concern in deceased…
  • 2022 American Transplant Congress

    Analysis of Hepatic Graft Survival in Extended Criteria Donors: Systematic Review and Meta-Analysis of Comparative Studies

    M. M. Pascale1, F. Frongillo1, G. Bianco1, I. Neri1, G. Dalla Riva2, M. Reale2, S. Agnes1, F. Giovinazzo1

    1General Surgery and Liver Transplant Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy, 2University of Canterbury, Canterbury, New Zealand

    *Purpose: Extended Criteria Donors include several definitions. These criteria vary across transplant centers and often rely on the center policy. The present meta-analysis analyzed graft…
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