Articles tagged "Graft survival"

2018 American Transplant Congress
Steroid Sparing Maintenance Immunosuppression is Associated with Decreased Mortality after Simultaneous Liver Kidney Transplantation
S. Weeks, X. Luo, C. Song, L. Pote, A. Gurakar, F. Navqi, B. Philosophe, A. Cameron, N. Desai, S. Ottmann, D. Segev, J. Garonzik Wang.
Johns Hopkins, Baltimore, MD.
Purpose: Significant variation in maintenance immunosuppression (mIS) regimens has been described between transplant centers for simultaneous liver kidney (SLK) transplant recipients; we sought to describe…
2018 American Transplant Congress
Ex Vivo Expanded Regulatory B Cells Promote Allograft Survival through IL-10-Dependent Pathway
K. Lee, K. Deng, L. Kojima, C. Dai, C. Rickert, H. Yeh, J. Markmann.
Massachusetts General Hospital, Boston.
Immunomodulatory capacity of B cells make them a promising therapeutic tool for autoimmune and alloimmune response in patients. We found that transplant tolerance induced by…
2018 American Transplant Congress
Post Reperfusion Portal Flow Rate Impacts Liver Allograft and Patient Survival in Patients with Pre Transplant Portal Vein Thrombosis
M. Rizzari, M. Safwan, M. Sobolic, S. Nagai, R. Schilke, K. Collins, A. Yoshida, M. Abouljoud.
Henry Ford Transplant Institute, Henry Ford Health System, Detroit, MI.
Background: Pre-transplant (pretx) portal vein thrombosis (PVT) not only makes the technical aspect of liver transplantation more challenging, it also is known to affect outcomes.…
2018 American Transplant Congress
Inflammation in Scarred Areas (i-IF/TA): Defining the Response to Standard Treatment of T Cell-Mediated Rejection in Kidney Recipients
D. Viglietti, O. Aubert, J-.P. Duong Van Huyen, A. Loupy, C. Lefaucheur.
Paris Translational Research Center for Organ Transplantation, Paris, France.
The 2017 Banff meeting has focused on the importance of defining the potential role of i-IF/TA as a component of the T cell-mediated rejection (TCMR)…
2018 American Transplant Congress
As Clear as Mud: Volatility of the Five-Tier Quality Assessment of Kidney Transplant Centers in the United States
J. Schold,¹ K. Andreoni,² A. Chandraker,³ R. Gaston,⁴ J. Locke,⁴ A. Mathur,⁵ T. Pruett,⁶ A. Rana,⁷ L. Ratner,⁸ L. Buccini.¹
¹Cleveland Clinic, Cleveland; ²University of Florida, Gainesville; ³Harvard Medical School, Boston; ⁴University of Alabama at Birmingham, Birmingham; ⁵Mayo Clinic, Phoenix; ⁶University of Minnesota, Minneapolis; ⁷Baylor College of Medicine, Houston; ⁸Columbia University, New York.
Outcomes of patients receiving transplants in the US are systematically aggregated into bi-annual Program-Specific Reports(PSRs) detailing risk-adjusted survival by transplant center. Recently the SRTR issued…
2018 American Transplant Congress
Dunbar Syndrome in Liver Transplantation: Results of a Single Center Matched-Pair Analysis and a European Survey Study
D. Morales-Santana,¹ Z. Czigany,¹ J. Böcker,¹ A. Andert,¹ W. Schöning,¹ T. Ulmer,¹ J. Bednarsch,¹ I. Amygdalos,¹ F. Meister,¹ P. Isfort,³ M. Liebl,³ D. Kroy,² F. Tacke,² C. Trautwein,² U. Neumann,¹ G. Lurje.¹
¹Department of Surgery and Transplantation, University Hospital RWTH, Aachen, Germany; ²Department of Internal Medicine III, University Hospital RWTH, Aachen, Germany; ³Institute of Radiology, University Hospital RWTH, Aachen, Germany.
Background: Median-arcuate-ligament or Dunbar-syndrome (MALs) potentially causes arterial complications in orthotopic liver transplantation (OLT). This study aimed to investigate MALs incidence and its impact on…
2018 American Transplant Congress
One-Year Graft Survival for Longevity Matched Kidneys in the Post-KAS Era
A. Wilk,¹ M. Aeder,² V. Casingal,³ N. Turgeon.⁴
¹United Network for Organ Sharing, Richmond, VA; ²University Hospitals Cleveland Medical Center, Cleveland, OH; ³Carolina's Healthcare, Charlotte, NC; ⁴Emory University, Atlanta, GA.
One of the key goals and achievements of KAS was to make better use of available kidneys by improving longevity matching between donor kidneys and…
2018 American Transplant Congress
Predicting Outcomes of Rat Vascularized Composite Allotransplants through Quantitative Measurement of Chimerism with PCR-Amplified Short Tandem Repeat
H. Cheng,¹ X. Huang,² C-.F. Lin,¹ N. AL Deek,² L. Shih,² C-.H. Lin,^1,2 F-.C. Wei.^1,2,3
¹Center for Vascularized Composite Allotransplantation, Linkou Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; ²Department of Plastic and Reconstructive Surgery, Linkou Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; ³College of Medicine, Chang Gung University, Gueishan, Taoyuan, Taiwan.
Background: Chimerism, defined as coexistence of donor and recipient cells, has been associated with induction and maintenance of tolerance to allotransplants. Although most studies have…
2018 American Transplant Congress
Prolonged-Release Tacrolimus Dosing in De Novo Kidney Transplantation: Randomized, Open-Label, Pilot Study
Y. Kim,¹ Y. Chiang,² S. Kim,³ M. Kim,⁴ S. Park,⁵ S. Wu,⁶ K. Horita,⁷ Y. Nakashima,⁷ H. Jiang,⁸ D. Han.¹
¹Asan Medical Center, Seoul, Korea; ²Chang Gung Memorial Hospital-Linkou, Taoyuan City, Taiwan; ³Samsung Medical Center, Seoul, Korea; ⁴Severance Hospital, Seoul, Korea; ⁵Dongsan Medical Center, Daegu, Korea; ⁶Tri-Service General Hospital, Taipei City, Taiwan; ⁷Astellas Pharma, Inc., Tokyo, Japan; ⁸Astellas Pharma, Inc., Maao, Singapore.
A multicenter, randomized, open-label, parallel-group, pilot, 52-wk study in Asian countries that assessed renal function, efficacy, and safety of low vs standard-dose prolonged-release tacrolimus (PRT)…
2018 American Transplant Congress
Impact of Aberrant Post-Transplant Laboratory and Blood Pressure Values on Graft Survival and Racial Disparities in Kidney Transplant
D. Taber, Z. Su, J. Fleming, N. Pilch, A. Posadas, V. Rao, P. Mauldin, D. Dubay.
MUSC, Charleston, SC.
Objective: The aim of this study was to assess the impact of post-transplant lab and blood pressure (BP) clinical data on graft survival and racial…