Articles tagged "Graft survival"

2018 American Transplant Congress
Outcome Analysis of Renal Re-Transplantation Compared to a Matched Control Group of First Transplantation
A. Schwarz,¹ F. Schaefer,¹ T. Framke,² S. Linnenweber,¹ H. Haller.¹
¹Nephrology, Hannover Medical School, Hannover, Germany; ²Biostatistics, Hannover Medical School, Hannover, Germany.
Background: 15% of our renal transplant program is re-transplantation (Tx2). We aimed to know if Tx2 has a higher risk than first transplantation (Tx1) and…
2018 American Transplant Congress
Is Kidney Transplantation Safe in Patients over 71 Years Old?
G. Andani, P. Tulissi, M. Gropuzzo, S. Crestani, C. Vallone, U. Baccarani, D. Montanaro, A. Risaliti.
Department of Kidney & Liver Transplantation, ASUIUD, Udine, Italy.
Introduction: Kidney transplantation in elderly patients is superior over dialysis as therapy for end stage renal disease (ESRD). We analyzed different parameters to evaluate patient…
2018 American Transplant Congress
Transplanting Kidneys from HCV-Infected Donors into HCV-Negative Recipients: Longer-Term and Extended Results of the THINKER Trial
D. Goldberg,¹ E. Blumberg,¹ P. Abt,¹ M. Levine,¹ P. Porrett,¹ A. Naji,¹ S. Nazarian,¹ D. Sawinski,¹ J. Trofe-Clark,¹ V. Van Deerlin,¹ C. Gentile,¹ J. Smith,¹ M. Kaminski,¹ A. Sicilia,¹ R. Hasz,² L. Suplee,² R. Reddy,¹ R. Bloom,¹ P. Reese.¹
¹University of Pennsylvania, Philadelphia; ²Gift of Life, Philadelphia.
Background: In 2016, 800 kidneys from HCV+ deceased donors were discarded. Short-term (6-month) data from the first 10 subjects in the THINKER-1 trial (NCT02743897; funder:…
2018 American Transplant Congress
Livers from Donation after Circulatory Death Donors Can Be Safely Used for Retransplantation
O. van Leeuwen,¹ M. van Reeven,² J. Erdmann,³ H. Metselaar,⁴ A. van den Berg,⁵ B. van Hoek,⁶ W. Polak,² R. Porte.¹
¹Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; ²Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands; ³Department of Surgery, Leiden University Medical Center, Leiden, Netherlands; ⁴Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Netherlands; ⁵Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, Netherlands; ⁶Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands.
Introduction: After donation after circulatory death (DCD) liver transplantation (LT), non-anastomotic biliary strictures (NAS) and early allograft dysfunction (EAD) are more frequently observed than after…
2018 American Transplant Congress
Should More Donation after Cardiac Death Livers Be Used in Pediatric Transplantation?
C. Hwang,¹ S. Levea,² M. MacConmara.¹
¹Surgery, UT Southwestern Medical Center, Dallas, TX; ²Medicine, UT Southwestern Medical Center, Dallas, TX.
Introduction: Multiple strategies exist to increase the organ pool for livers in pediatric recipients, including using split livers, high risk livers, and donation after cardiac…
2018 American Transplant Congress
Urinary C5b-9 is an Independent Predictor of Graft Failure in Renal Transplant Recipients
R. Lammerts, M. Eisenga, M. Alyami, M. Seelen, M. Daha, J. van den Born, S. Bakker, S. Berger, On behalf of the COMBAT Comsortium.
Department of Nephrology, University Medical Centre Groningen, Groningen, Netherlands.
IntroductionChronic antibody-mediated rejection is thought to be the main cause of late kidney-allograft loss, involving donor-specific antibody–mediated activation of the complement system. Activation of filtered…
2018 American Transplant Congress
Histone Deacetylase-6 Inhibition Mitigates Liver Ischemia-Reperfusion Injury and Acetaminophen Toxicity in Mice
S. Concors,¹ D. Murken,¹ D. Aufhauser,¹ Z. Wang,¹ G. Ge,¹ T. Bhatti,⁴ W. Hancock,^3,4 M. Levine.^1,2
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Surgery, Children's Hospital of Philadelphia, Philadelphia, PA; ³Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; ⁴Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
Introduction: Ischemia/reperfusion injury (IRI) leads to poor outcomes and early graft loss in liver transplantation. Understanding the mechanisms of liver IRI may aid in prevention…
2018 American Transplant Congress
Pancreas and Kidney Co-Transplantation in Type II Diabetes: A Single Center Experience
J. Choi, J. Jung, H. Kwon, S. Shin, Y. Kim, D. Han.
Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University Ulsan College of Medicine, Seoul, Korea.
Background: Diabetic CKD patients present increased morbidity and mortality due to cardiovascular complications. Pancreas transplantation can restore insulin independence in patients with type I diabetes…
2018 American Transplant Congress
Long-Term Social Outcome after Pediatric Kidney Transplantation
Y. Hamasaki,¹ T. Matsuda,¹ M. Kubota,¹ J. Hashimoto,¹ Y. Takahashi,¹ M. Muramatsu,² T. Kawamura,³ K. Sakai,² S. Shishido.^1,2
¹Pediatric Nephrology, Toho University Faculty of Medicine, Tokyo, Japan; ²Nephrology, Toho University Faculty of Medicine, Tokyo, Japan; ³Nephrology, Sakura Medical Center, Toho University, Sakura, Japan.
BackgroundPatients' and graft survival rates after pediatric kidney transplantation (KTx) were recently improved because of progress in immunosuppressants, perioperative care, and operative procedures. Therefore the…
2018 American Transplant Congress
Time-Effect of Donor and Recipient Characteristics on Graft Survival after Kidney Transplantation
E. Molmenti,¹ J. Yang,³ C. Molmenti,² E. Grodstein,¹ H. Rilo,¹ L. Teperman.¹
¹Surgery, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY; ²Feinstein Institute, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY; ³Epidemiology, Mailman Schoool of Public Health, Columbia University, New York, NY.
BackgroundThe current kidney allocation system (KAS) is based on the Kidney Donor Profile Index (KDPI) and the Estimated Post-Transplant Survival (EPTS), quality-based “longevity matching” strategies…