ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2018 American Transplant Congress

    FSGS Recurrence and Graft Survival in Pediatric Renal Transplants: A NAPRTCS Registry Analysis

    L. Koh,1 K. Martz,2 T. Blydt-Hansen.3

    1Starship Children's Health, Auckland, New Zealand; 2EMMES Corp., Rockville; 3BC Children's Hospital, Vancouver, Canada.

    IntroductionPrevious studies have raised concern of adverse outcome of living donor (LD) grafts in children transplanted for FSGS. This study reassesses impact of donor source,…
  • 2018 American Transplant Congress

    Aggressive Pursuit of Donation after Cardiac Death Kidney Donors with High Kidney Donor Profile Index: Good Use of Resources?

    J. Rogge, C. Hostetler, B. Nicely, S. Rudich.

    Clinical Division, Gift of Life Michigan, Ann Arbor, MI.

    Pursuit of donation after cardiac death (DCD) organ donors requires a significant investment in resources. As an Organ Procurement Organization which very aggressively pursues such…
  • 2018 American Transplant Congress

    Long-Term Prognosis of BK Virus Associated Nephropathy in Kidney Transplant Recipients

    W. Park,1,3 S. Yeo,1 S. Kang,1,3 H. Park,1 K. Jin,1,3 S. Park,1,3 M. Choe,2,3 S. Han.1,3

    1Internal Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea; 2Pathology, Keimyung University School of Medicine, Daegu, Republic of Korea; 3Keimyung University Kidney Institute, Daegu, Republic of Korea.

    Background: BK virus-associated nephropathy (BKVAN) is an important risk factor that results in an allograft loss in kidney transplant recipients (KTRs). The short-term prognosis of…
  • 2018 American Transplant Congress

    Death-Censored Graft Failure (DCGF) Post Kidney Transplant (KTx) is Usually the Result of Rapid Loss of Function after Periods of Stability

    R. Gaston,1 L. Hunsicker,2 A. Fieberg,3 A. Matas,3 The DeKaf Consortium.

    1CTI Clinical Trial & Consulting, Covington, KY; 2Int. Med., U Iowa, Iowa City, IA; 3Biostatistics and Surgery, U Minnesota, Minneapolis, MN.

    Late graft dysfunction leading to clinically indicated transplant biopsy (KTxBx) is a better predictor of subsequent DCGF than baseline data and early post-transplant events (Gaston…
  • 2018 American Transplant Congress

    A Single Center Outcomes Analysis of UNOS Defined "Hard to Place Kidneys"

    Y. Qazi, K. Lee, A. Jones, L. Aguirre, M. Parma, M. Smogorzewski, T. T. Maw, L. Sher.

    Keck Medical Center at USC, Los Angeles, CA.

    The discard rate of potentially usable kidneys remains dismal despite a critical shortage of organs. The Scientific Registry of Transplant Recipients (SRTR) now provides a…
  • 2018 American Transplant Congress

    Thirty-Six Consecutive Kidney Transplants in Recipients with Atypical Hemolytic Uremic Syndrome: A Single-Centre Experience

    E. Favi,1 G. Ardissino,2 D. Cresseri,3 J. Brocca,1 S. Testa,4 F. Tel,4 A. Giussani,1 C. Colico,1 C. Beretta,1 M. Ferraresso.1

    1Kidney Transplantation, Fondazione IRCCS Ca' Granda, Milan, Italy; 2Centre for HUS Prevention, Control and Management, Fondazione IRCCS Ca' Granda, Milan, Italy; 3Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy; 4Pediatric Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy.

    Background. Due to high recurrence rate, poor kidney transplant (KTx) survival has been reported for recipients with atypical hemolytic uremic syndrome (aHUS). More recently, prophylaxis…
  • 2018 American Transplant Congress

    The Impact of Donor Specific Alloantibodies on Long-Term Outcomes of Liver Re-Transplantation

    Q. Xu,1 A. Skaro,2 V. McAlister.2

    1Department of Pathology and Lab Medicine, University of Western Ontario, London, ON, Canada; 2Department of Surgery, University of Western Ontario, London, ON, Canada.

    Despite reports that associate donor specific antibody (DSA) with rejection after liver transplantation, grafts are still allocated according to blood group (ABO) but not human…
  • 2018 American Transplant Congress

    Novel Vascular Inflow Offers Renal Transplantation to Recipients with Severe Central and Peripheral Vascular Disease

    S. Mao,1 E. Giorgakis,2 A. Moss,2 T. Taner.1

    1William J. von Liebig Center for Transplantation, Mayo Clinic, Rochester, MN; 2Transplantation Surgery, Mayo Clinic, Phoenix, AZ.

    Background: Absence of suitable implant locations for donor renal vessels may be a major problem in patients with significant central and peripheral vascular disease. We…
  • 2018 American Transplant Congress

    Lymph Node Stromal Laminins Affect Graft Survival through Regulation of CD4 T Cell Proliferation and Migration

    L. Li, T. Simon, W. Piao, Y. Xiong, V. Saxena, T. Zhang, C. Wagner, J. Bromberg.

    University of Maryland, Baltimore, MD.

    Background: Our prior studies demonstrated that tolerance and immunity are associated with differential expression of lymph node (LN) stromal laminins α4β1γ1 (411) and α5β1γ1 (511),…
  • 2018 American Transplant Congress

    Sensing T Cell Killing Activity with Granzyme B Activity Probes

    Q. Mac,1 D. Mathews,2 J. Kahla,1 C. Stoffers,1 O. Delmas,1 B. Holt,1 A. Adams,2 G. Kwong.1

    1Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA; 2Department of Surgery, Emory University School of Medicine, Atlanta, GA.

    Purpose: We developed activity-based probes that sense Granzyme B (GzmB) activity during alloreactive T cell killing of donor cellsMethods: FITC-labelled GzmB substrate (IEFDSG) was synthesized…
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