Articles tagged "Graft survival"

2018 American Transplant Congress
Comparison of Low Dose and Very Low Dose Extended-Release Tacrolimus / MMF in De Novo Kidney Transplant Recipients- 3 Years Follow-Up
S. Narumi,¹ Y. Watarai,¹ N. Goto,² T. Hiramitsu,¹ M. Tsujita,² M. Okada,¹ K. Futamura,² T. Kobayashi.³
¹Transplant Surgery, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Aichi, Japan; ²Transplant Nephrology, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Aichi, Japan; ³Kidney Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.
Recently, once-daily tacrolimus extended-release formulation (TACER) has been accepted in kidney transplantation, however its optimal dosing are not well evaluated. We have validated low dose…
2018 American Transplant Congress
A Natural Herb Danshen Suppresses Allospecific Memory CD8+ T Cell Generation and Murine Allograft Rejection
Z. Dai, H. Liu, Y. Chen, C-.L. Liang, F. Qiu.
Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
Inducing long-term transplant survival or tolerance without continuous global immunosuppression is a highly desired goal in transplantation given that conventional immunosuppressive drugs may cause side…
2018 American Transplant Congress
Elevated Donor Terminal Creatinine Does Not Appear to Be Associated with Worse Outcomes in Kidney Transplantation
S. Rayhill, J. Haldorson.
U Washington, Seattly.
There is justified reluctance to use kidneys from donors with significantly elevated creatinine as they may have severe, irreversible injury. Recently, thanks, in part to…
2018 American Transplant Congress
Feasibility of a National Class II Matching Strategy for Pediatric Kidney Transplant Candidates
T. Blydt-Hansen,¹ W. Klement,² K. Tinckam,³ J. Gill.¹
¹University of British Columbia, Vancouver, Canada; ²Canadian Blood Services, Ottawa, Canada; ³University of Toronto, Toronto, Canada.
Antibody-mediated rejection (AMR) is a major concern for allograft failure, which could be mitigated by allocation of Class II matched donors. Since children have priority,…
2018 American Transplant Congress
T Cell-Mediated Rejection Poses Greater Risk to Graft Survival Than Antibody-Mediated Rejection in Heart Transplants
M. Parkes, K. Famulski, P. Halloran, The INTERHEART Study Group.
University of Alberta, Edmonton, Canada.
Purpose: In kidney transplants, failure post-biopsy is associated with acute injury transcript expression reflecting the histologically silent tissue response-to-wounding (JCI 120:1862) and antibody-mediated rejection (ABMR),…
2018 American Transplant Congress
Outcomes of Organ Transplantation from Donors with Cancer History
Z. Guo,¹ X. He,¹ S. Huang.¹
¹Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; ²Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, Sun Yat-sen University, Guangzhou, China; ³Guangdong Provincial International Cooperation Base of Science and Technology, Sun Yat-sen University, Guangzhou, China.
Purpose: The inherent challenges of selecting an acceptable donor for each of the increasing numbers and acuity of recipients has led programs to take increased…
2018 American Transplant Congress
The Etiologies and Impact of Hospitalization in Older Kidney Transplant Recipients
M. Posadas Salas, R. Rodriguez, P. Amaechi, V. Rao, D. Taber.
Medical University of South Carolina, Charleston, SC.
Older kidney transplant recipients (KTR) face challenges of post-transplant complications related to frailty and comorbidities. They are particularly vulnerable to infectious complications. This study elucidates…
2018 American Transplant Congress
Donor Derived Transmissions in 2016-2017: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)
C. Wolfe, S. Tlusty, G. Vece, R. Bag, G. Berry, J. Bucio, L. Danziger-Isakov, D. Florescu, D. Goldberg, C. Ho, R. La Hoz, K. Lilly, M. Malinis, A. Mehta, M. Nalesnik, R. Sawyer, L. Strasfeld, P. Wood, N. Theodoropoulos, M. Michaels.
DTAC, United Network for Organ Sharing, Richmond, VA.
The DTAC evaluates unanticipated potential donor-derived transmission events (PDDTE), including mostly infections (I) & malignancies (M), to assess for likelihood of donor transmission. Reporting policy…
2018 American Transplant Congress
Sufficient Hepatic Artery Flow Redeems Poor Portal Vein Flow after Liver Transplantation in Patients with Porta Vein Thrombosis
L. Coromina Hernandez, K. Sasaki, D. Firl, J. McVey, M. Fujiki, F. Aucejo, B. Eghtesad, C. Quintini, C. Miller, K. Hashimoto.
General Surgery, Cleveland Clinic, Cleveland, OH.
Objective:Although portal vein thrombosis(PVT) in liver transplantation is no longer a contraindication, it remains technically challenging. Insufficient intraoperative PV flow after PV thrombectomy/reconstruction was reported…
2018 American Transplant Congress
Combined Heart–Kidney Compared to Isolated Heart Transplant in Patients with Chronic Kidney Disease – A Single Center Experience
D. Gauvin, A. Bhalla, W. McCallum, A. Vest, N. Goyal.
Tufts University School of Medicine, Boston, MA.
Background: Severe irreversible renal dysfunction has been a contraindication for heart transplant (HTx); however, combined heart-kidney transplant (HKTx) is an accepted therapeutic option for concomitant…