2018 American Transplant Congress
10-Year Outcomes of Renal Transplantation from Circulatory Death Donors with Increased Terminal Creatinine
Surgery III, Tokyo Women's Medical University, Tokyo, Japan.
Background: To alleviate chronic renal graft shortages in Japan, donation after circulatory death (DCD) is an increasingly used organ resource. Organs from DCD donors with…2018 American Transplant Congress
TLR-Activated Bregs Promote Islet Allograft Tolerance in an IL-10-Independent and TGF-β-Dependent Manner
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
Background: We previously demonstrated the potent capacity of regulatory B cells (Bregs) to mitigate allograft immunity. Recently, we produced TLR-activated B cells in vitro that…2018 American Transplant Congress
Complement Activating HLA Class 2 Antibodies Are Associated with Poor Renal Allograft Survival; Multicentre Study
IntroductionRole of Class I and II pre-formed complement activating antibodies on renal outcomes is not well defined. In this multicentre study, we looked at the…2018 American Transplant Congress
Delayed Graft Function in Simultaneous Liver Kidney Transplantation
Purpose: Increased rates of delayed graft function (DGF) after simultaneous liver kidney (SLK) transplantation have been described, as well as inferior graft survival in patients…2018 American Transplant Congress
Individualized Immunosuppression through Risk-Stratification in Renal Transplantation Preserves Excellent Outcomes at Three Years
University of Virginia Health System, Charlottesville, VA.
Risk-stratification of renal transplant recipients based on immunologic risk factors allows for tailored immunosuppression (IS), but long term follow up is limited. This study evaluates…2018 American Transplant Congress
Identification of Anti-Inflammatory and Pro-Inflammatory Gut Microbiota That Determine Graft Survival
Introduction: The gut microbiota induce and train the host immune system. Whether microbiota from contrasting environments of colitic or pregnant mice are pro- or anti-inflammatory…2018 American Transplant Congress
The Impact of Aorto-Iliac Calcifications on Patient and Graft Survival in Renal Transplant Recipients Using the TASC II Classification
Introduction: Kidney transplantation (KTx) is the therapy of choice in patients with end-stage renal disease. Aorto-iliac calcifications (AIC) are a relative contra-indication for KTx, even…2018 American Transplant Congress
Kidney Transplantation in ESKD Patients with a History of Sickle Cell Disease/Trait
Introduction:Kidney transplantation in Sickle Cell Disease patients is fraught with complications, including increased risk of infection and thrombosis. We present long term outcomes of patients…2018 American Transplant Congress
The Regulatory Role of Plasma Cells (as Bregs) is Counterbalanced by a NOVEL Inflammatory Role in Murine Transplant and Autoimmune Models
Plasma Cells (PCs; B220lowCD138hiBlimp1+Ig+) in LN and spleen were shown to be the major source of B cell lineage IL-10, and absence of PCs worsens…2018 American Transplant Congress
Outcomes from 194 Consecutive Split Left Liver Transplants: Comparison of Living versus Deceased Donors
Recanati/Miller Transplant Institute, Mount Sinai Hospital, New York.
Methods:Analysis of long term outcomes of 194 consecutive left lateral segment grafts (LLS) including 94 living (LD) and 99 deceased (DD) donor grafts (1992 -…
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