ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2018 American Transplant Congress

    Does DGF Result in Worse Outcomes in a Second Transplant?

    B. Muth,1 B. Astor,1,2 J. Blazel,1 J. Turk,1 D. Mandelbrot,1 A. Djamali,1 S. Parajuli.1

    1Department of Medicine, University of Wisconsin, Madison, WI; 2Department of Population Health, University of Wisconsin, Madison, WI.

    Delayed graft function (DGF) is a risk factor for patient death, kidney allograft loss, reduced allograft function and acute rejection after kidney transplantation. Prior transplant…
  • 2018 American Transplant Congress

    Clinically Relevant Variation of Donor-Derived Cell-Free DNA during Longitudinal Surveillance of Renal Allografts

    M. Narayanan,1 T. Alhamad,2 D. Hiller,3 J. Yee,3 R. Woodward,3 J. Bromberg.4

    1Texas A&M Health Science Center, Temple, TX; 2Washington University School of Medicine, St. Louis, MO; 3CareDx, Brisbane, CA; 4University of Maryland School of Medicine, Baltimore, MD.

    Purpose: Donor-derived cell-free DNA (dd-cfDNA) levels >1% are associated with active rejection in renal transplant recipients. This report defines the clinically relevant variation of dd-cfDNA…
  • 2018 American Transplant Congress

    Recurrent FSGS Post-Transplantation: Prevalence and Risk Factors

    R. Aguiar,1 A. Gasparini,2 P. Chowdhury,1 D. Game,1 D. Moutzouris.1

    1Department of Nephrology and Transplantation, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom; 2Department of Health Sciences, University of Leicester, Leicester, United Kingdom.

    Introduction: Primary FSGS can recur in the renal allograft and is associated with poor outcomes. The aim of this study was to assess the prevalence…
  • 2018 American Transplant Congress

    Treatment of Active Chronic Antibody-Mediated Rejection with Rituximab, IVIG and Plasma Exchange

    G. Piñeiro,1 J. Rovira,2 E. De Sousa-Amorim,1 J. Villarreal,1 M. Sole,3 I. Revuelta,1 M. Lozano,4 E. Palou,4 F. Oppenheimer,1 J. Campistol,1 F. Diekmann.1,2

    1Nephrology and Renal Transplantation, Hospital Clinic de Barcelona, Barcelona, Spain; 2Laboratori Experimental de Nefrologia i Trasplantament (LENIT), Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain; 3Pathology, Hospital Clinic de Barcelona, Barcelona, Spain; 4Apheresis Unit, Hemotherapy and Hemostasis, Hospital Clinic de Barcelona, Barcelona, Spain; 5Immunology, Hospital Clinic de Barcelona, Barcelona, Spain.

    Chronic antibody-mediated rejection (cABMR) and transplant glomerulopathy (TG) are main features associated with long-term graft loss. Despite its clinical significance, the available evidence on treatment…
  • 2018 American Transplant Congress

    Improving Prediction of Post-Transplant Death and Graft Loss with Expanded Clinical Data Collection

    R. Sung,1 J. Magee,1 M. Schnitzler,2 N. Dzebisashvili,3 K. Lentine,2 L. Ly,1 D. Axelrod.4

    1University of Michigan, Ann Arbor; 2Saint Louis University, St. Louis; 3XynManagement, Inc, St. Louis.

    US transplant centers are graded for patient and graft survival of their recipients based on comparison to risk-adjusted expectations using elements captured in the national…
  • 2018 American Transplant Congress

    Significant Alteration in Transplant Center Performance Assessment with Extended Patient Follow Up Time

    J. Schold, D. Goldfarb, S. Flechner, A. Wee, E. Poggio.

    Cleveland Clinic, Cleveland.

    IntroductionCurrent transplant center performance models focus on 1-year graft and patient survival as primary outcomes. This is despite that 2.5 year cohorts are used to…
  • 2018 American Transplant Congress

    Validation Study of Operational Tolerance Signatures in Korean Kidney Transplantation Recipients

    J. Seo,1 Y. Lee,1 Y. Kim,1 J. Moon,1 K-.H. Jeong,1 C-.D. Kim,2 J. Park,3 B. Jeong,4 S-.H. Lee.1

    1Department of Nephrology, School of Medicine, Kyung Hee University, Seoul, Korea; 2Department of Nephrology, Kyung-pook National University School of Medicine, Daegu, Korea; 3Department of Nephrology, Sungkyunkwan University, Samsung Hospital, College of Medicine, Seoul, Korea; 4Department of Nephrology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

    Background:A peripheral B cell population was significantly higher in drug-free operationally tolerant patients than those with stable graft function or acute rejection under standard immunosuppression.…
  • 2018 American Transplant Congress

    Effect of Ethnicity on Recipient Characteristics, Kidney Transplant Provision and Outcomes in a High-Volume National Health Service Hospital

    E. Favi,1 C. Puliatti,2 M. Ferraresso,1 R. Cacciola.2

    1Kidney Transplant, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy; 2Kidney Transplant, Barts Health NHS Trust, The Royal London Hospital, London, United Kingdom.

    Background. Several reports have demonstrated that outcomes of kidney transplantation (KTx) can be influenced by recipient's ethnicity and social status. However, available data mostly refer…
  • 2018 American Transplant Congress

    Is It Better Choice to Perform Kidney Transplantation for Elderly CKD Patients?

    R. Imamura,1 K. Tsutahara,2 K. Yamanaka,3 M. Kawamura,1 S. Nakazawa,1 T. Kato,1 T. Abe,1 H. Kishikawa,3 N. Ichimaru,4 K. Nishimura,3 S. Yamaguchi,2 N. Nonomura.1

    1Urology, Osaka University Graduate School of Medicine, Suita, Japan; 2Urology, Osaka General Medical Center, Osaka, Japan; 3Urology, Hyogo Prefectural Nishinomiya Hospital, Nishinomiya, Japan; 4Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, Suita, Japan.

    [Objectives] Japan is forecasted to become an aged society with 30.3% and 39.9% in 2025 and 2060, respectively. Along with that, the number of elderly…
  • 2018 American Transplant Congress

    Exploring the Viability of Kidneys Discarded in the US: A Comparison of Kidney Utilization Patterns and Outcomes in the US and France

    O. Aubert, P. Reese, M. Raynaud, D. Viglietti, C. Loheac, N. Kamar, M. Delahousse, C. Legendre, D. Glotz, C. Lefaucheur, A. Loupy.

    Paris Translational Center for Organ Transplantation, Paris, France.

    Approximately 2,000 donated kidneys are discarded in the US each year. Some transplant leaders have questioned the viability of these lost organs, while others suggest…
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