2022 American Transplant Congress
Recurrence of Membranous Nephropathy After Kidney Transplantation – TANGO Consortium
1Harvard Medical School, Boston, MA, 2Mount Sinai, New York, NY
*Purpose: Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults. Several breakthroughs in recent decades, including the identification of anti-PLA2R Abs, aided…2022 American Transplant Congress
Elevated Donor-Derived Cell-Free DNA (dd-cfDNA) in the Early Post-Transplant Period is Associated with an Increased Incidence of Adverse Clinical Outcomes in Kidney Transplant Recipients
*Purpose: Early post-transplant elevations in dd-cfDNA, even in the absence of histologic rejection or other overt pathology, have been suggested to carry a risk of…2022 American Transplant Congress
Cold Ischemia Time is More Critical for Older Donor Kidney Survival: A Machine Learning Approach
*Purpose: Increasing utilization of kidneys from older donors is a potential solution to mitigate the organ shortage. However, older donor age is a risk factor…2022 American Transplant Congress
Utility of Urinary CTGF as a Biomarker of Progressive Allograft Dysfunction in Pediatric Renal Transplant Recipients
*Purpose: Previous reports from a number of studies indicate that renal allograft recipients who have inflammatory infiltrates within areas of interstitial fibrosis with tubular atrophy…2022 American Transplant Congress
Recipient MCPggaac Haplotype is Associated with Poor Graft Survival in Recipients with De Novo Thrombotic Microangiopathy
*Purpose: De novo thrombotic microangiopathy (TMA) is associated with poor kidney graft survival. We aimed to assess the role of common complement haplotypes in kidney…2022 American Transplant Congress
Study Of Matrix Metalloproteinases(MMP) And Tissue Inhibitors Of Metalloproteinases(TIMP) In Renal Transplant Recipients(RTR)- Rejectors Versus Stable Graft
*Purpose: Our study aimed to shed light on the role of serum levels of MMP and their inhibitors- TIMP in renal allograft rejection.*Methods: This was…2022 American Transplant Congress
Temporal Changes in the Peripheral Immune Profile of Acute Rejection Highlight New Mechanisms of Alloimmunity and Potential Non-Invasive Biomarkers of Rejection in Pediatric Liver Transplantation
*Purpose: Acute rejection (AR) is common in pediatric liver transplantation (LT) and can impact late graft loss. Immune subpopulations mediating AR in LT have not…2022 American Transplant Congress
Donor Macrophage Depletion Improves Kidney Graft Function Despite Long Cold Ischemia
1Duke University School of Medicine, Durham, NC, 2Medicine, Duke University, Durham, NC
*Purpose: Prolonged cold ischemia is a known risk factor for delayed graft function and poorer outcomes after kidney transplantation. Overcoming this obstacle is key to…2022 American Transplant Congress
Possible Recurrence Must Not Limit Kidney Transplantations for Patients with Focal Segmental Glomerulosclerosis
Istituto Giannina Gaslini, Genova, Italy
*Purpose: Non-genetic forms of Focal Segmental Glomerulosclerosis (FSGS) are at high risk of recurrence after kidney transplant (KT) (55%), when compared to inherited forms (0-4%)…2022 American Transplant Congress
Comparison of Outcomes and Management of COVID Infection Among Kidney Transplant Recipients Between Pre-Vaccination Rollout Era and Post-Vaccination Rollout Era
*Purpose: The COVID pandemic has posed a significant challenge among kidney transplant recipients (KTR) due to their immunocompromised states. The effects of COVID vaccination on…
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