Articles tagged "Graft survival"

2019 American Transplant Congress
The Use of dd-cfDNA as a Predictive Tool for Outcome Decreased Kidney Function
T. Alhamad¹, E. Poggio², D. Hiller³, S. Dholakia³, P. Sood⁴
¹Washington University School of Medicine, St. Louis, MO, ²Cleveland Clinic, Cleveland, OH, ³CareDx, Brisbane, CA, ⁴University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: A decline in estimated glomerular filtration rate (eGFR) during the first 12 months following kidney transplantation is associated with poor outcome and increased graft…
2019 American Transplant Congress
Portal-endocrine And Gastric-exocrine Drainage Technique In Pancreatic Transplantation
G. Zibari, B. Samant, R. McMillan, N. Singh, H. Shokouh-Amiri
Willis-Knighton Regional Transplant Center, Shreveport, LA
*Purpose: Pancreas Transplant (PTx) is an established treatment for patients with diabetes mellitus. Diagnosis of rejection has continued to be problematic. In 2007, a new…
2019 American Transplant Congress
AMD3100 and Low-Dose FK506 Prevent De Novo Donor Specific Antibody Formation and Rejection in a Sensitized Kidney Transplantation Model
A. R. Ahmadi, L. Qi, R. N. Wesson, A. M. Cameron, Z. Sun
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: De novo donor specific antibody (DSA) formation and antibody mediated rejection (AMR) are the main cause of allograft failure long-term. We have developed a…
2019 American Transplant Congress
Renal Failure after Liver Transplantation: Benefits from a Little Pinch of KALT
R. Ruiz¹, K. Holmes², G. McKenna¹, N. Onaca¹, G. Testa¹, H. Fernandez¹, J. Bayer¹, A. Wall¹, E. Martinez¹, E. Martinez¹, A. Gupta¹, R. Goldstein¹, G. Klintmalm¹
¹Baylor All Saints Medical Center, Fort Worth, TX, ²Medical City Fort Worth, Fort Worth, TX
*Purpose: The development and consequences of renal failure after liver transplantation (LT) are well-chronicled. Kidney after liver transplantation (KALT) is the preferred treatment in this…
2019 American Transplant Congress
Renal Allograft Survival after Dual Kidney Transplantation is at Least as Favorable as Outcome after Expanded Criteria Donor Kidney Transplantation
A. Brar¹, M. Sattar¹, A. Gruessner¹, R. M. Jindal², R. Nee³, R. Gruessner¹, M. Salifu¹
¹SUNY Downstate Medical Center, Brooklyn, NY, ²Department of Surgery,, USU-Walter Reed Uniformed Services University, Bethesda, MD, ³USU-Walter Reed Uniformed Services University, Bethesda, MD
*Purpose: Dual kidney transplantation (DKT) is the implantation of two adult kidneys from a marginal donor into a single recipient. DKT may play an important…
2019 American Transplant Congress
Causes of 30 Day Graft Loss among Shared Kidneys in the National Kidney Registry (NKR)
J. Verbesey¹, A. Thomas², M. Ronin³, D. Segev⁴, A. Waterman⁵, S. Flechner⁶, M. Cooper¹
¹Georgetown University Hospital, Washington, DC, ²University of North Carolina, Chapel Hill, NC, ³National Kidney Registry, New York, NY, ⁴Johns Hopkins University, Baltimore, MD, ⁵UCLA, Los Angeles, CA, ⁶Cleveland Clinic, Cleveland, OH
*Purpose: We have previously reported favorable 1 year graft survival of over 98% in the NKR. Many early concerns associated with organ travel, longer ischemic…
2019 American Transplant Congress
Impact of T-cell Mediated Allograft Inflammation within First-Year after Kidney Transplantation: An Analysis of Paired Biopsies from a Single Center Study
S. Tandukar, R. Mehta, I. Owoyemi, D. Jorgensen, P. Sood, S. Hariharan
Division of Transplant Nephrology, Thomas E. Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: We evaluated the impact of Clinical and Sub-Clinical T-Cell-Mediated Rejection (TCMR) and Sub-Clinical Inflammation (SCI) within 1 year post-transplant.*Methods: Adult kidney transplant patients who…
2019 American Transplant Congress
Pediatric Heart and Lung Graft Loss during the “High-Risk Age Window”
J. Long¹, J. Motter¹, K. R. Jackson¹, M. Kosztowski¹, B. Orandi², X. Luo¹, K. Van Arendonk³, A. Massie¹, E. Bush¹, R. S. Higgins¹, D. L. Segev¹, J. M. Garonzik-Wang¹
¹Johns Hopkins School of Medicine, Baltimore, MD, ²University Of Alabama at Birmingham, Birmingham, AL, ³Children’s Hospital of Wisconsin-Milwaukee Campus, Milwaukee, WI
*Purpose: Pediatric kidney transplant recipients experience a high-risk age window of increased graft loss during late adolescence and early adulthood (17-24 years), termed emerging adulthood.…
2019 American Transplant Congress
Transition from Pediatric to Adult Care of Kidney Transplant Recipients: A Retrospective Analysis of a French Monocentric Cohort
M. Mazloum¹, M. Charbit², O. Aubert¹, D. Anglicheau¹, A. Scemla¹, R. Salomon², P. Krug², C. Legendre¹, R. Sberro-Soussan¹
¹Adult Nephrology and Renal Transplantation Department, Necker Hospital, Paris, France, ²Pediatric Nephrology and Renal Transplantation Department, Necker Hospital, Paris, France
*Purpose: Transition refers to the dynamic process in which the patient is oriented from pediatric to adult care. In the field of kidney transplantation, transition…
2019 American Transplant Congress
Microparticle Delivery to Lymph Nodes Induces Specific Suppression to Prolong Islet Survival
Y. Xiong¹, L. Tostanoski², C. Jewell³, J. Bromberg¹
¹Surgery, U. Maryland, Baltimore, MD, ²U.Maryland, Baltimore, MD, ³U. Maryland, College Park, MD
*Purpose: Microparticles (MP) loaded with peptide antigen plus other immune signals and delivered directly into lymph nodes (LN) can result in either proinflammatory or antiinflammatory…