2020 American Transplant Congress
Graft Survival after Liver Transplantation for Patients with Cholangiocarcinoma
Vanderbilt University Medical Center, Nashville, TN
*Purpose: Liver transplantation (LT) with neoadjuvant chemoradiation is increasingly utilized for the treatment for unresectable cholangiocarcinoma (CCA), however, post-LT graft survival is not well described.…2020 American Transplant Congress
Immune Checkpoint PD-L1 Pathway as an Effective Platform for Localized Immunomodulation to Attain Indefinite Allogeneic Islet Graft Survival
*Purpose: Allogenic islet transplantation is an effective therapeutic approach for the treatment of T1D. However, chronic immunosuppression to control rejection is a major limitation. The…2020 American Transplant Congress
Renoportal Vein Graft for Complete Portal Vein Thrombosis: A Reproducible Technique for a Challenging Problem
Baylor University Medical Center, Dallas, TX
*Purpose: Type-IV Yerdel portal vein thrombosis (PVT) was historically contraindicated in liver transplant due to lack of appropriate portal vein inflow. Renoportal vein graft (RPVG)…2020 American Transplant Congress
Changes in Gut Microbiota and Acute Rejection after Kidney Transplantation
*Purpose: Kidney transplantation (KT) is the best treatment for end-stage renal disease. Although rejection is a normal immune response of the body to a foreign…2020 American Transplant Congress
Treatment of De Novo Renal Transplant Recipients with Calcineurin Inhibitor (CNI)-Free, Belatacept+Everolimus-Based Immunosuppression
*Purpose: Compared with CNI-based immunosuppression, kidney transplant recipients receiving belatacept-based treatment present with a favorable metabolic profile, reduced chronic allograft nephropathy, and improved renal function,…2020 American Transplant Congress
Myeloid Derived Suppressor Cells Expanded by Granulocyte-Colony Stimulating Factor Prolong Allogeneic Cardiac Graft Survival When Compared with MDSCs Expanded by Different Means
Department of Surgery, University of Maryland, Baltimore, MD
*Purpose: Myeloid-derived suppressor cells (MDSCs) inhibit T cell responses and may provide a pathway towards tolerance. Granulocyte-colony stimulating factor (GCSF) is used in clinical practice…2020 American Transplant Congress
Extracorporeal Membrane Oxygenation in Pediatric Liver Transplantation
*Purpose: Extracorporeal membrane oxygenation (ECMO) can be used for oxygen preservation and hemodynamic support in case of circulatory or respiratory failure. Although the role of…2020 American Transplant Congress
Liver Transplant Recipients with BMI 40 to <50 kg/m2 Have Excellent Patient and Graft Survival
University of Wisconsin School of Medicine and Public Health, Madison, WI
*Purpose: Obesity rates in the United States (US) have reached nearly 40%, which has led to an increasing proportion of liver transplant (LT) candidates with…2019 American Transplant Congress
Room for Optimism; Improvement in Long-Term Patient and Graft Survival of Kidney Transplants in the United States over the past Three Decades
Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: Previous studies indicated that the short-term (1 year) allograft survival of kidney transplants has improved significantly over the years. However, less is known about…2019 American Transplant Congress
B Cell-Specific IRE1a Deficiency Protects Renal Allografts from Rejection via Inhibition of Donor-Specific Antibodies and Induction of B Regulatory Cells
*Purpose: Despite the progress in immunosuppressive regimens, antibody-mediated rejection remains a major contributor to renal allograft loss in recipients with donor-specific antibodies (DSA). IRE1a, an…
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