Articles tagged "Graft survival"

2020 American Transplant Congress
Impact of Allograft Nephrectomy on Outcomes in Second Kidney Transplantation
N. Sato, Y. Kakuta, T. Kanzawa, K. Unagami, M. Okumi, H. Ishida, K. Tanabe
Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan
*Purpose: The impact of failed allograft nephrectomy on the outcome of second kidney transplantation is not clear. We evaluated the effects of the first allograft…
2020 American Transplant Congress
Treg Protection of the Allograft Depends on Lymphotoxin Beta Receptor Expression in Lymphatic Endothelial Cells
V. Saxena¹, W. Piao¹, L. Li¹, Y. Xiong¹, C. Palusckievicz¹, T. Simon¹, M. Shirkey¹, R. Abdi², J. S. Bromberg¹
¹University of Maryland, Baltimore, Baltimore, MD, ²Harvard U, Boston, MA
*Purpose: Regulatory T cell (Treg) migration to afferent lymphatics and lymph nodes (LN), and suppressive function, require Treg lymphotoxin alpha (LTα) to stimulate LT beta-receptor…
2020 American Transplant Congress
One Year of COIIN Outcomes: Did Cohorts A and B Maintain Graft Survival?
J. Foutz, R. J. Carrico, K. Sisaithong, H. Tosoc-Haskell, D. Klassen
United Network for Organ Sharing, Richmond, VA
*Purpose: The Collaborative Innovation and Improvement Network (COIIN) was a 3-year OPTN project aimed at increasing the utilization of kidneys with a kidney donor profile…
2020 American Transplant Congress
Hydroxychloroquine is Associated with Better Patient and Graft Survival in Kidney Transplant Patients with Lupus Nephritis as Cause of ESRD
T. Singh¹, S. Garg², S. Panzer¹
¹Nephrology, University of Wisconsin, Madison, WI, ²Rheumatology, University of Wisconsin, Madison, WI
*Purpose: Hydroxychloroquine (HCQ) use leads to better patient and renal survival in patients with lupus nephritis (LN). Whether the clinical benefits of HCQ extends to…
2020 American Transplant Congress
Clinical Significance of C4d and HLA-DSA on Post-Transplant Clinical Outcomes in Kidney Transplant Recipients with Antibody-Mediated Rejection
W. Park, O. Kwon, Y. Kim, J. Paek, K. Jin, S. Park, S. Han
Internal Medicine, Keimyung University School of Medicine, Keimyung University Kidney Institute, Daegu, Korea, Republic of
*Purpose: The clinicopathological diagnosis of rejection after kidney transplantation (KT) was well defined by Banff classification. In the diagnosis of antibody-mediated rejection (AMR), the presence…
2020 American Transplant Congress
Human Thrombomodulin Gene Expression on Genetically Modified Donor Pig Hearts is Correlated with Long Term Xenograft Survival
A. K. Singh, C. Goerlich, G. Braileanu, A. Hersfield, T. Zhang, I. Tatarov, B. Lewis, F. Sentz, D. Ayares, K. Horvath, D. Kaczorowski, B. Griffith, M. M. Mohiuddin
Department of Surgery, University of Maryland Baltimore, Baltimore, MD
*Purpose: Thrombomodulin (TBM) is a coagulation regulatory protein which has shown a protective role against coagulation dysregulation and prevented thrombotic microangiopathy and premature loss of…
2020 American Transplant Congress
Validation of Prognostic Index for Allograft Outcome in Kidney Transplant Recipients with Transplant Glomerulopathy
M. Talwar¹, V. Balaraman¹, A. Bhalla¹, O. Cseprekal², M. Yazawa¹, P. S. Podila³, A. Azhar¹, L. N. Cossey⁴, J. D. Eason¹, M. Z. Molnar¹
¹James D. Eason Transplant Institute, Methodist University Hospital, Memphis, TN, ²Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary, ³Faith & Health Division, Methodist Le Bonheur Healthcare, Memphis, TN, ⁴Arkanalabs, Little Rock, AR
*Purpose: Kidney transplant recipients with Transplant Glomerulopathy (TG) have very poor allograft survival compared to those without TG. The objective of this research was to…
2020 American Transplant Congress
Specific Gut Microbiota Community Suppresses Acute Rejection by Reducing Natural Killer Cell Population
W. Zhang, L. Gong, Y. Xu, X. Hu
Department of Urology, Capital Medical University Beijing Chaoyang Hospital, Urology Institute of Capital Medical University, Beijing, China
*Purpose: The gut microbiota community was reported to be altered by high-dose FK506 treatment, while fecal microbiota transplantation with such microbiota plus low-dose FK506 could…
2020 American Transplant Congress
Long-Term Outcome of Kidney Transplantation for IgA Nephropathy: A Single-Center Experiences
M. Tasaki¹, K. Saito¹, Y. Nakagawa², N. Imai³, Y. Ito³, K. Takahashi⁴, Y. Tomita¹
¹Division of Urology, Department of Regenerative & Transplant, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, ²Division of Urology, Juntendo University, Tokyo, Japan, ³Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, ⁴Otsukadai Clinic, Tokyo, Japan
*Purpose: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide, with a high recurrence rate after kidney transplantation (KTx). The aim of this…
2020 American Transplant Congress
Third and Fourth Kidney Re-Transplants: A 20-Year Single Centre Experience
O. O. Okidi¹, A. Hassan¹, S. Bhutani¹, A. Summers¹, K. Poulton², C. Fullwood¹, D. VanDellen¹, J. Worthington², T. Augustine¹
¹Transplant and Endocrine Surgery, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom, ²Transplantation Laboratory, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, United Kingdom
*Purpose: Re-transplantation may be associated with management dilemmas including repeat allocation of limited kidney allografts to same individuals in the face of an increasing waiting…