2022 American Transplant Congress
Living Donor Kidney Transplant in Recipients with Glomerulonephritis: Donor Recipient Biologic Relationship and Allograft Outcomes
1Nephrology, University of Minnesota, Minneapolis, MN, 2MHealth, Minneapolis, MN
*Purpose: Controversies exist over the impact of donor-recipient biologic relationship on the outcomes of living donor kidney transplant in recipients with glomerulonephritis (GN). The improved…2022 American Transplant Congress
Clinical Significance of the Living Kidney Donor Profile Index in Living Kidney Donors for Predicting of Post-Transplant Outcome: Korean Organ Transplantation Registry
*Purpose: According to recent reports, a risk index for living donor kidney transplantation (LDKT) such as the Kidney donor profile index (KDPI), a non-invasive method…2022 American Transplant Congress
Fibroblastic Reticular Cell Lama4 Regulates T Cell Migration to Lymph Nodes and Adaptive Immunity
1Surgery, UMB, Baltimore, MD, 2Harvard University, Boston, MA
*Purpose: Lymph node (LN) stromal laminin α4 (Lama4) is associated with tolerance. We hypothesized that fibroblastic reticular cell (FRC) derived Lama4 contributes to a tolerogenic…2022 American Transplant Congress
Depletion of Donor Macrophages Permits Post-Transplant Tolerance Induction
*Purpose: Using donor splenocytes fixed with cross-linker ethylcarbodiimide (ECDI-SPs), our lab has induced tolerance in a variety of murine and non-human primate models when one…2022 American Transplant Congress
Recurrence of Membranous Nephropathy After Kidney Transplantation – TANGO Consortium
1Harvard Medical School, Boston, MA, 2Mount Sinai, New York, NY
*Purpose: Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults. Several breakthroughs in recent decades, including the identification of anti-PLA2R Abs, aided…2022 American Transplant Congress
Elevated Donor-Derived Cell-Free DNA (dd-cfDNA) in the Early Post-Transplant Period is Associated with an Increased Incidence of Adverse Clinical Outcomes in Kidney Transplant Recipients
*Purpose: Early post-transplant elevations in dd-cfDNA, even in the absence of histologic rejection or other overt pathology, have been suggested to carry a risk of…2022 American Transplant Congress
Cold Ischemia Time is More Critical for Older Donor Kidney Survival: A Machine Learning Approach
*Purpose: Increasing utilization of kidneys from older donors is a potential solution to mitigate the organ shortage. However, older donor age is a risk factor…2022 American Transplant Congress
Utility of Urinary CTGF as a Biomarker of Progressive Allograft Dysfunction in Pediatric Renal Transplant Recipients
*Purpose: Previous reports from a number of studies indicate that renal allograft recipients who have inflammatory infiltrates within areas of interstitial fibrosis with tubular atrophy…2022 American Transplant Congress
Recipient MCPggaac Haplotype is Associated with Poor Graft Survival in Recipients with De Novo Thrombotic Microangiopathy
*Purpose: De novo thrombotic microangiopathy (TMA) is associated with poor kidney graft survival. We aimed to assess the role of common complement haplotypes in kidney…2022 American Transplant Congress
Study Of Matrix Metalloproteinases(MMP) And Tissue Inhibitors Of Metalloproteinases(TIMP) In Renal Transplant Recipients(RTR)- Rejectors Versus Stable Graft
*Purpose: Our study aimed to shed light on the role of serum levels of MMP and their inhibitors- TIMP in renal allograft rejection.*Methods: This was…
American Transplant Congress abstracts