2022 American Transplant Congress
Experience Using Intra-Operative Dialysis in Surgically Complex Liver Transplantation
1Anesthesiology, Ochsner, New Orleans, LA, 2Surgery, Ochsner, New Orleans, LA
*Purpose: At our high-volume center, we often perform liver transplantation (LT) on surgically complex patients that includes re-transplantation, prior open liver resection, bariatric surgeries, extensive…2022 American Transplant Congress
Role of Urinary Biomarkers in RWE Clinical Paradigm
1Nephrosant, Brisbane, CA, 2NephroSant, Brisbane, CA
*Purpose: Due to heterogeneity observed in the kidney transplant population, it has been extremely challenging for traditional methods such as histopathology to predict graft outcomes.…2022 American Transplant Congress
Il-33 Induced Regulatory Macrophages Inhibit Transplantation Immune Rejection by Inducing Tregs
Beijing Chaoyang Hospital, Beijing, China
*Purpose: The occurrence of acute and chronic rejections after transplantation are key factors that affect the survival of the recipients. Induction of transplantation immune tolerance…2022 American Transplant Congress
Prospective Study of Preimplantation Biopsy in Deceased Donor Kidney Transplantation (DDKT)
*Purpose: Our aim was to study the impact of preimplantation biopsy (Bx) findings in selecting kidneys from more marginal donors.*Methods: This is a 2-year prospective…2022 American Transplant Congress
Successful Use of Anti-IL-6R Therapy to Achieve Cardiac Allograft Tolerance in Non-Human Primates
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA
*Purpose: In contrast to kidney allografts, attempts to achieve tolerance of isolated cardiac allografts in non-human primates (NHPs) using a mixed chimerism strategy have been…2022 American Transplant Congress
Inflammation After Kidney Transplantation Is Associated With Overall- And Death-censored Graft Loss
Department of Transplantational Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway
*Purpose: Early graft loss after kidney transplantation (KT) is mainly a result of acute rejection, while long-term graft loss episodes are often dependent on multifactorial…2022 American Transplant Congress
Histologic Predictors of Graft Loss in Early Clinically Indicated Biopsies After Kidney Transplantation
*Purpose: We aimed to investigate histopathological predictors of graft lost in patients who underwent clinically indicated biopsies for worsening kidney function and/or proteinuria within 3…2022 American Transplant Congress
Autophagy is an Important Factor in the Development of Fibrosis Following Renal Injury; Implications for Post-Transplant IFTA
*Purpose: Interstitial Fibrosis and Tubular Atrophy (IFTA) is the most common cause of long-term graft failure following renal transplant. There is currently no effective therapy.…2022 American Transplant Congress
Dendritic Cell Senescence as a Key Contributor to Transplant Rejection
1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD
*Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…2022 American Transplant Congress
CT Based Iliac Vessel Calcification Scoring: Long Term Patient and Allograft Outcomes
The Royal London Hospital - Barts Health NHS Trust, London, United Kingdom
*Purpose: Coronary calcification is a known indicator of poor cardiac outcomes. Similarly, iliac and distal vascular calcification has been shown to be an adverse outcome…