2015 American Transplant Congress
Single Infusion of Donor-Type Splenocytes Treated With Extracorporeal Photopheresis Prior to Transplantation Significantly Prolongs Cardiac Allograft Survival in Mice
Background: Extracorporeal Photopheresis (ECP) is an immune therapy in which blood leukocytes are treated with 8-methoxypsoralen (8-MOP), exposed to UV-A light, and re-infused. This study…2015 American Transplant Congress
Kidney Transplant Outcomes in Recipients Older Than 70: A Single Center Experience
Indiana University Health, Indianapolis, IN.
Age is no longer considered a contraindication to renal transplantation. To date, little is known in regards to the grafts and patients outcomes in elderly…2015 American Transplant Congress
ABO-Incompatible Liver Transplantation for Severe Hepatitis B Patients
Objectives: Effect of ABO-incompatible liver transplantation on severe hepatitis B (SHB) patients is still unclear. Herein, we described 22 successful cases of patients with SHB…2015 American Transplant Congress
Liver-Specific Transcription Factor ATF5 Participates in Regulation of IFN-γ/B7-H1 Signaling Pathway in Liver Mesenchymal Cells
Liver transplant tolerance was initially discovered in pigs, rats and mice. A recent paper reviewed ∼400 liver transplant patients worldwide who had undergone weaning of…2015 American Transplant Congress
Human Leukocyte Antigen Mismatch and Steroid Maintenace in Kidney Transplantation
Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA.
Kidney transplant recipients (KTRs) with zero/minimal HLA mismatches against their donors enjoy superior long term outcomes related to diminished immune response of the recipient against…2015 American Transplant Congress
Everolimus and Early Calcineurin Inhibitor Withdrawal Is Associated With Superior Renal Function: 5-Year Follow-Up of the Randomized PROTECT Liver Transplantation Study
PROTECT Study Group, Novartis Pharma GmbH, Germany.
Purpose: At the end of the 12-month (M) PROTECT core study (NCT00378014), de novo liver transplant recipients (LTxR) who switched from a calcineurin inhibitor (CNI)…2015 American Transplant Congress
Thymoglobulin Administration During Multi-Visceral and Isolated Small Bowel Procurement Does Not Adversely Affect the Survival of Harvested Organs
Anti-thymocyte globulin administration in donors before intestinal procurement may result in decreased graft versus-host disease (GVHD) due to reduced recipient lymphocyte trafficking after reperfusion. Reluctance…2015 American Transplant Congress
A Novel Post-Transplant High-Dose Cyclophosphamide-Based Regimen to Promote Immune Tolerance After VCA
Background: VCA has become a viable treatment option for devastating tissue defects. However, the life-long need of immunosuppressive medications curtails the wider use of VCA.…2015 American Transplant Congress
Gene Expression of Kidney Biopsies Reveals Common Mechanisms of Rejection and a Cluster of Co-Expressed Genes Predictive of Long-term Outcomes
1The Scripps Research Institute, La Jolla; 2Northwestern University, Chicago.
Purpose: Acute rejection (AR) still affects 8-14% of kidney transplants and rates of 10-year graft loss remain unchanged in part due to chronic rejection (CR).…2015 American Transplant Congress
Kidneys from Living Donors With High Body Mass Index Do Not Have Inferior Outcomes
Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
The disparity between donor kidney availability and demand has increased utilization of kidneys from marginal living donors. Data regarding outcome of transplantation from living donors…
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