2015 American Transplant Congress
Prospective Study of a Steroid Free, Low Dose Tacrolimus and Everolimus Combination Regimen in Kidney Transplant
Calcineurin(CNI) based therapy is the cornerstone of immunosuppresion(IS) after kidney transplant. However chronic nephrotoxicity from CNI as been implicated in post-transplant renal dysfunction. We hypothesized…2015 American Transplant Congress
Comparison of T Regulatory (Treg) Cell Function Pre- and Post-Lung Transplantation Shows a Major Negative Impact of Immunosuppression on Treg Function
Aim: Clinical lung Tx recipients do not have sustained long-term survival outcomes comparable to that of other recipients of solid organ allografts, despite generally comparable…2015 American Transplant Congress
Clinically Relevant Anti-TCR mAb Induction Plus Brief Rapamycin Therapy Can Achieve Long-Term Vascularized Composite Allograft (VCA) Survival
Aim: Current strategies for management of VCA recipients are adapted from solid organ transplant protocols, and almost universally employ induction therapy followed by maintenance triple…2015 American Transplant Congress
Belatacept-Treated Patients Had Better Graft Survival at 7-Years Post-Transplant Compared With Cyclosporine-Treated Patients: Final Results from BENEFIT
Background: At 3yrs, improvement in renal function was seen in kidney transplant recipients treated with belatacept (bela) vs cyclosporine (CsA) in BENEFIT. Here we report…2015 American Transplant Congress
Kidney Allocation Tool of the Future: The Estimated Post-Transplant Survival (EPTS) Score
University of Maryland, Baltimore.
Background:Beginning December 2014, a new kidney transplant allocation system will be used. A component of this system is the Estimated Post-Transplant Survival (EPTS) score, which…2015 American Transplant Congress
Analysis of the Temporal Evolution of Causes of Graft Loss Among Kidney Transplant Recipients in a US Southern State
The past decade of kidney transplantation has seen many changes in immunosuppression (IS), donor, and recipient characteristics. This study analyzes the associations between the aforementioned…2015 American Transplant Congress
National Outcomes of Donation After Cardiac Death (DCD) Liver Transplantation Are Equivalent to Donation After Brain Death (DBD) Liver Transplantation Using Older (DBD) Donor Livers
University of Wisconsin, Madison, WI.
Background: Multiple studies have demonstrated that outcomes of DCD liver transplantation (LTx) are inferior to DBD LTx. Thus DCD liver transplantation represents only 7% of…2015 American Transplant Congress
CD8 T Cell Biomarkers Improves the Capacities of the Kidney Transplant Failure Score for the Long-Term Prognostic of Kidney Graft Failures
Background. Kidney transplantation is acknowledged as the treatment of choice for patients in end-stage renal disease compared to dialysis. We hypothesized that the efficiency of…2015 American Transplant Congress
Intrapatient Variability of Tacrolimus Blood Concentrations Following Renal Transplant – Acute Rejection or No Connection?
Background: A high degree of intrapatient variability (IPV) of tacrolimus blood concentrations has been associated with poor long-term outcome (1). Periods of under-exposure with increased…2015 American Transplant Congress
Outcomes of ABO Incompatible Kidney Transplantation in Children
Purpose: ABO blood group incompatible transplantation (ABOi) has become increasingly common over the last decade, in part due to a shortage of suitable deceased donor…
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