ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2015 American Transplant Congress

    Single Center Experience of C4d Staining of Kidney Transplant Biopsies

    R. Prashar, L. Yessayan, M. Goggins, V. Karthikeyan, K. Venkat, A. Patel.

    Division of Nephrology and Transplant Institute, Henry Ford Hospital, Detroit, MI.

    Introduction: While a diffuse positivity (>50%) of C4d in kidney transplant peritubular capillaries strongly co-relates with the presence of acute or chronic antibody mediated rejection,…
  • 2015 American Transplant Congress

    ABO-Incompatible Live Donor Kidney Transplants Inferior to ABO-Compatible Transplants, but Match Deceased Donor Results: Is Kidney Paired Donation the Answer?

    J. Verbesey, M. Cooper, A. Gilbert, M. Grafals, P. Weems, J. Moore, S. Ghasemian, C. Nilubol, B. Javaid.

    Georgetown University School of Medicine, MedStar Georgetown Transplant Institute, Kidney and Pancreas Transplant Program, Washington, DC.

    Objective: Compare kidney allograft survival in ABO-incompatible (ABO-I) and ABO-compatible (ABO-C) live donor kidney transplant recipients.Methods: We analyzed UNOS database for patients who underwent a…
  • 2015 American Transplant Congress

    Role of Innate Immune Cells in Chronic Allograft Loss and Novel Strategies to Target Them

    C. Wu,1,2 P. Zhao,1 W. Liu,1 X. Xiao,1 X. Shi,1 Y. Peng,1 M. Kloc,1 X. He,2 M. Ghobrial,1 X. Li.1

    1Center for Immunobiology and Transplantation Research, Houston Methodist Hospital and Houston Methodist Research Institute, Houston, TX; 2Organ Transplant Center, 1st Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.

    Despite remarkable improvements in short term transplant survival, the long-term outcome of allografts remains poor in the clinic, and most transplants are eventually lost due…
  • 2015 American Transplant Congress

    Kidney Plasmacytoid Dendritic Cells Display Distinct Cell Surface Markers and May Explain the Induction of Tolerance by Kidney Allografts

    N. Oh, M. Tonsho, D. Ndishabandi, R. Colvin, J. Madsen, A. Alessandrini.

    Massachusetts General Hospital, Boston, MA.

    Achieving tolerance in heart allografts is an important area of research as the need for heart transplantations increase. Recent studies in non-human primates (NHPs) have…
  • 2015 American Transplant Congress

    Retrospective Cohort Study Concerning Efficacy and Safety of Bortezomib in Combination With Or Without Rituximab in Antibody Mediated Rejection in Renal Transplant Recipients

    M. Duerr, N. Lachmann, K. Budde, J. Waiser.

    Charité Universitätsmedizin Berlin, Department of Nephrology, Berlin, Germany.

    Treatment of antibody-mediated rejection (AMR) in renal transplant (tx) patients (pts) is still challenging and long-term outcome remains unsatisfying. Because plasma cells (PCs) are crucial…
  • 2015 American Transplant Congress

    Pancreatic Islet Survival Under Confinement

    A. Rodriguez, S. Sigrist, E. Maillard.

    UMR DIATHEC EA 7294, Centre Européen d'Etude du Diabète, Strasbourg, France.

    The main advantage of cell therapy is the possibility to immune-isolate the graft in a device to avoid immune suppressive regimen. In islet transplantation field,…
  • 2015 American Transplant Congress

    Immunological Evaluation of Acellular Extracellular Matrix Upon Transplantation

    M. Ketaki,1 P. Pradeep,1 N. Nikhil,1 G. Dellgren,3 H. Suchitra, M. Olausson.2

    1Laboratory for Transplantation Regenerative Medicine, Surgery, Gothenburg University, Gothenburg, Sweden; 2Department of Surgery, SU/Sahlgrenska University Hospital, SE 41345, Gothenburg, Sweden; 3Cardiothoracic Surgery, Transplant Institute, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.

    Background : To mitigate the scanty supply of donor organs, porcine tissues can be utilized since, it embrace the potential to accomplish the task of…
  • 2015 American Transplant Congress

    The Impact of Center Volume on Simultaneous Kidney-Pancreas Transplantation Outcomes

    A. Malone,1 D. Brennan,1 J. Wellen,2 T. Alhamad.1

    1Transplantation Nephrology, Renal Division, Washington University, St Louis; 2Section of Transplant Surgery, Washington University, St Louis.

    Background: Pancreas transplantation is associated with a high incidence of surgical complications and successful outcomes require experienced surgical and post-transplant care. Prior studies have linked…
  • 2015 American Transplant Congress

    Intermittent High Dose Intravenous Immunoglobulin as Treatment for Donor Specific Antibodies in Renal Transplant Recipients

    P. Bolin,1 K. Parker,2 F. Rana,1 W. Bryant,1 P. Jawa,1 R. Harland.3

    1Internal Medicine, East Carolina University, Brody School of Medicine, Greenville, NC; 2Vidant Medical Center, Greenville, NC; 3Surgical Immunology and Transplantation, East Carolina University, Brody School of Medicine, Greenville, NC.

    Background: Donor-specific HLA antibody (DSA) formation in post-renal transplant patients is associated with chronic rejection and graft failure. Previous studies in our population have indicated…
  • 2015 American Transplant Congress

    No Significant Outcome Benefit for Brand-Name Versus Generic Tacrolimus in Kidney Transplant Recipients: SRTR Analysis

    D. Goldfarb,1 E. Poggio,1 S. Flechner,1 R. Fatica,1 J. Schold.2

    1Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    IntroGeneric formulations of tacrolimus have been available for maintenance immunosuppression since 2009. Our aim was to evaluate the frequency of use of generic tacrolimus and…
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