2015 American Transplant Congress
Single-Center Analysis of Adult, Combined Heart-Liver Transplant (CHLT) Recipients
Background: Combined heart-liver transplantation (CHLT) is life-saving for patients with end-stage heart-liver diseases. This is a review of patients who underwent CHLT at a single-center.Methods:…2015 American Transplant Congress
Anti-BTLA Antibody (6B2) Induced Prolongation of Fully MHC-Mismatched Murine Cardiac Allograft and Generation of Foxp3+ Regulatory T Cells
Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA; CD272) has been implicated in the regulation of autoimmune and may potentially play an important…2015 American Transplant Congress
Outcomes of Patients With Hepatocellular Carcinoma Receiving a Donation After Cardiac Death Liver Graft
Background: Recent data suggests that patients with Hepatocellular carcinoma (HCC) who receive a donation after cardiac death (DCD) graft have inferior graft and patient survival…2015 American Transplant Congress
The Gut Microbiota Regulates Murine Cardiac Transplant Outcome
1University of Maryland, Baltimore, MD; 2University of Hohenheim, Stuttgart, Germany.
Hypothesis: The gut microbiota regulates systemic immunity. Different characteristics of the microbiota can be defined that have pro- or anti-inflammatory effects. We tested the hypothesis…2015 American Transplant Congress
Neighborhood Poverty Modifies Gender Disparities in Kidney Transplant Outcomes
Earlier studies report mixed findings comparing transplant outcomes in women versus men, and little is known about the association of socioeconomic status (SES) with gender…2015 American Transplant Congress
Depression of Complement Regulatory Factors in Human and Rat Renal Grafts in Association With Progress of Acute Cellular Rejection
Introduction and ObjectiveIt is commonly known that complements play important roles in antibody mediated rejection in renal transplantation. However, the association of complements with progression…2015 American Transplant Congress
Three Year Outcomes of Renal Allograft Transplants in African American Recipients Receiving Alemtuzumab for Induction Immunosuppression
Ochsner Clinic Foundation, New Orleans, LA.
Background:Induction with Alemtuzumab is well documented to reduce the incidence and severity of acute rejection episodes, which may improve graft survival. Limited data are available…2015 American Transplant Congress
Immunologic Long-Term Outcome of Living Kidney Transplantation Depending On the Donor-Recipient Relationship
Nephrology, Charite Universitaetsmedizin Berlin, Berlin, Germany.
Background. Only few data is available about long-term immunologic outcomes of living kidney transplantation (KTx) depending on the donor-recepient relationship.Patients and methods. This single center…2015 American Transplant Congress
Donor Hemodynamic Profile Presages Graft Survival in Donation After Cardiac Death Liver Transplantation
Transplant Institute, Georgetown University Hospital, Washington, DC.
IntroductionDonation after cardiac death (DCD) grafts are prone to periods of prolonged hypoxemia and hypotension prior to donor expiration, leading to an increased complication rate,…2015 American Transplant Congress
Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allografts by Combination of Anti-BTLA mAb (6B2) and Anti-PD-1 mAb (PIM-2)
Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA) and Programmed death (PD)-1 had been suggested to have immunomodulatory activity. This study investigated the…
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