ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2016 American Transplant Congress

    Endoscopic Polydimethylsiloxane Injection in Prevention of Recurrent Graft Pyelonephritis for Transplanted Kidney with Vesicoureteral Reflux.

    L. Nison,1 M. Hazzan,2 P. Puech,3 S. Bouye.1

    1Urology, University of Lille, Lille, France; 2Nephrology, University of Lille, Lille, France; 3Radiology, University of Lille, Lille, France.

    Reccurent acute graft pyelonephritis (AGPN) with vesicoureteral reflux (GVUR) can have a deleterious impact on graft outcome. The objective of this study was to evaluate…
  • 2016 American Transplant Congress

    Profiling of T Cell Subsets in a Primate Cardiac Transplant Model.

    N. O'Neill, T. Zhang, G. Braileanu, W. Sun, X. Cheng, C. Evans, R. Pierson, A. Azimzadeh.

    Surgery, University of Maryland, Baltimore, MD.

    Purpose: Costimulation blockade prolongs graft survival but does not induce tolerance in primates, and mechanisms of rejection are incompletely understood. Here we evaluate changes in…
  • 2016 American Transplant Congress

    Impact of Donor AKI on Outcome Following High KDPI Deceased Donor Kidney Transplantation.

    D. Haakinson,1 I. Qaqish,2 M. Smith,3 H. Khamash,2 K. Reddy,1 R. Heilman.2

    1Transplant Surgery, Mayo Clinic Arizona, Phoenix, AZ; 2Nephrology, Mayo Clinic Arizona, Phoenix, AZ; 3Pathology, Mayo Clinic Arizona, Phoenix, AZ.

    Background: Transplanting deceased donor kidneys with AKI does not appear to have negative impact on graft survival, however the impact of AKI on high KDPI…
  • 2016 American Transplant Congress

    Kidney Graft Homing of De Novo Donor Specific HLA Antibodies Is an Early Step within the Antibody-Mediated Graft Damage Process.

    A. Nocera,1 M. Cioni,2 A. Tagliamacco,1 A. Innocente,3 I. Fontana,4 A. Magnasco,2 A. Nocco,3 A. Sementa,2 G. Garibotto,1 G. Ghiggeri,2 M. Cardillo,3 P. Comoli,5 F. Ginevri.2

    1Transplant Immunology and Nephrology, University of Genova, Genova, Italy; 2Nephrology and Pathology, G. Gaslini Institute, Genova, Italy; 3Transplantation Immunology, Fondazione Cà Granda Ospedale Maggiore Policlinico, Milano, Italy; 4Kidney Transplant Surgery, IRCCS S.Martino-IST, Genova, Italy; 5Pediatric Hematology/Oncology, IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy.

    In this study, by a parallel analysis on sera and graft biopsies we have analyzed, in a pediatric cohort of unsensitized recipients of a first…
  • 2016 American Transplant Congress

    Kidney Transplant with Low Level DSA and Low Positive B-Flow Crossmatch: An Underappreciated Option for Highly Sensitized Transplant Candidates.

    C. Schinstock, W. Cheungpasitporn, F. Cosio, D. Mitema, M. Gandhi, M. Prieto, P. Dean, M. Stegall.

    Transplant Center, Mayo Clinic, Rochester, MN.

    Introduction: Avoiding DSA is difficult in sensitized patients. A kidney transplant (KTx) with low level DSA with or without a low level B flow cytometric…
  • 2016 American Transplant Congress

    The Burden and Outcomes of Fractures in Kidney Transplant Recipients.

    N. Atagu, T. Nguyen, N. Phan, O. Famure, Y. Li, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.

    Background: Kidney transplantation confers an increased risk for bone fractures. However, there is poor consensus on the incidence of fractures in kidney transplant recipients (KTRs),…
  • 2016 American Transplant Congress

    Impact of Early Hospital Readmission Following Simultaneous Pancreas Kidney Transplantation.

    E. King, L. Kucirka, M. McAdams-DeMarco, M. Bowring, A. Massie, D. Segev.

    Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.

    BACKGROUND: Our group recently demonstrated that 54% of simultaneous pancreas kidney (SPK) recipients experience early hospital readmission (EHR). It is unknown whether EHR following SPK…
  • 2015 American Transplant Congress

    Comparison of T Regulatory (Treg) Cell Function Pre- and Post-Lung Transplantation Shows a Major Negative Impact of Immunosuppression on Treg Function

    T. Akimova,1 J. Diamond,2 D. Wilkes,3 D. Lederer,4 J. Christie,2 W. Hancock.1

    1Path & Lab Med, CHOP & UPenn, Philadelphia; 2Pulm, Allergy & Crit Care Med, UPenn, Philadelphia; 3Med, Microbiol & Immunol, Indiana Uni Sch of Med & Thoracic Transplant Prog, Indianapolis; 4Medicine, Columbia Uni, New York.

    Aim: Clinical lung Tx recipients do not have sustained long-term survival outcomes comparable to that of other recipients of solid organ allografts, despite generally comparable…
  • 2015 American Transplant Congress

    Clinically Relevant Anti-TCR mAb Induction Plus Brief Rapamycin Therapy Can Achieve Long-Term Vascularized Composite Allograft (VCA) Survival

    L. Wang, A. Samanta, J. Huang, T. Bhatti, Z. Wang, R. Han, L. Levin, M. Levine, W. Hancock.

    CHOP/UPenn, Philadelphia.

    Aim: Current strategies for management of VCA recipients are adapted from solid organ transplant protocols, and almost universally employ induction therapy followed by maintenance triple…
  • 2015 American Transplant Congress

    Belatacept-Treated Patients Had Better Graft Survival at 7-Years Post-Transplant Compared With Cyclosporine-Treated Patients: Final Results from BENEFIT

    F. Vincenti,1 J. Grinyó,2 L. Rostaing,3 K. Rice,4 S. Steinberg,5 M. Moal,6 M. Polinsky,7 U. Meier-Kriesche,7 C. Larsen.8

    1Univ of Calif, San Francisco; 2Univ Hosp Bellvitge, Barcelona, Spain; 3Univ Hosp and INSERM U563,IFR-BMT, Toulouse, France; 4Baylor Univ Med Ctr, Dallas; 5Sharp Memorial Hosp, San Diego; 6Hôp de La Cavale Blanche, Brest, France; 7BMS, Lawrenceville; 8Emory Univ Transpl Ctr, Atlanta.

    Background: At 3yrs, improvement in renal function was seen in kidney transplant recipients treated with belatacept (bela) vs cyclosporine (CsA) in BENEFIT. Here we report…
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