ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2022 American Transplant Congress

    Liver Transplant Outcomes Using Grafts with Early Allograft Dysfunction

    S. Y. Ohara1, E. Macdonough2, G. Mahdi3, L. Egbert3, B. Lizaola-Mayo2, W. Hewitt4, A. Mathur4, A. Moss4, K. Reddy4, B. Aqel4, C. Jadlowiec4

    1Division of Surgery, Valleywise Health Medical Center, Creighton University, Phoenix, AZ, 2Division of Gastroenterology and Hepatology, Mayo Clinic Arizona, Phoenix, AZ, 3Mayo Clinic Alix School of Medicine, Phoenix, AZ, 4Division of Transplant Surgery, Mayo Clinic Arizona, Phoenix, AZ

    *Purpose: The significance of early allograft dysfunction (EAD) and its impact on liver transplant (LT) outcomes remains debated. Our study aimed to assess LT outcomes…
  • 2022 American Transplant Congress

    Inferior Kidney Transplant Outcomes in Young Adults Transplanted as Children

    K. Deville, F. Rosenblum, D. R. Kelly, M. Seifert

    UAB School of Medicine, Birmingham, AL

    *Purpose: Adolescence (age 13-17 years) has been identified as a high-risk age interval for pediatric kidney transplant recipients, with accelerated rates of late acute rejection…
  • 2022 American Transplant Congress

    Polarized Il-6 Secretion from Lymphatic Endothelial Cells Promotes Treg Conversion to Extregs

    V. Saxena1, W. Piao1, L. Li1, M. W. Shirkey1, R. Lakhan1, S. Walden2, K. L. Hippen2, B. Blazar2, J. S. Bromberg1

    1University of Maryland School of Medicine, Baltimore, MD, 2University of Minnesota, Minneapolis, MN

    *Purpose: Regulatory T cell (Treg) suppressor function and allograft protection depend on maintenance of transcription factor Foxp3 expression and lymphatic migration. Lymphatic endothelial cell (LEC)…
  • 2022 American Transplant Congress

    Transitional-1 B Cell IL-10/TNFα Ratio Risk-Stratifies Renal Transplant Patients with Early Borderline Change

    A. Cherukuri, P. Randhawa, S. Hariharan, D. Rothstein

    Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA

    *Purpose: Recent studies have shown that Banff borderline change (BLC) on allograft biopsies (Bx) is associated with decreased graft survival. However, many patients with BLC…
  • 2022 American Transplant Congress

    Efficacy and Safety of a Delayed Graft Function Protocol in Kidney Transplant Recipients

    V. Vu1, S. Bhayana2, H. Sweiss1, N. Castro1, R. Hall1, J. Nelson1

    1University Health, San Antonio, TX, 2University of Texas Health Science Center at San Antonio, San Antonio, TX

    *Purpose: To evaluate the efficacy and safety of a protocol increasing the net state of immunosuppression for adult kidney transplant recipients (KTR) with delayed graft…
  • 2022 American Transplant Congress

    Feasibility and Short-Term Outcomes of Kidney Transplantation Following Donation After Circulatory Death Using Thoracic Normothermic Regional Perfusion in the United States

    L. Hickman, D. Shaffer, J. Hoffman, W. G. McMaster, A. S. Shah, R. Forbes

    Surgery, Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Organ donation after circulatory death (DCD) is an important component of kidney transplants in the US. Cardiac transplantation from DCD donors has previously been…
  • 2022 American Transplant Congress

    A Novel IL-2 Mutein Selectively Expands Regulatory T Cells and Prolongs Skin Graft Survival

    O. Efe1, T. J. Borges1, R. B. Gassen1, L. Morena1, A. Al Jurdi1, I. T. Lape1, G. J. Bobcock2, J. C. Madsen1, L. V. Riella1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, 2Visterra, Inc., Waltham, MA

    *Purpose: Promoting immune regulation through expansion of regulatory T cell (Treg) may allow immunosuppression minimization and improve long-term graft outcomes. Low-dose IL-2 is known to…
  • 2022 American Transplant Congress

    Month 1 Donor Derived Cell Free DNA Levels Predict Future Kidney Transplant Rejection

    B. M. Kinsella1, K. Guo1, C. Rebello1, L. Zhao1, S. Park2, J. Friedewald1

    1Northwestern University, Chicago, IL, 2Transplant Nephrology, Northwestern University, Chicago, IL

    *Purpose: The purpose of this study was to determine if donor-derived cell-free DNA (dd-cfDNA) can be used one-month post-transplant to predict later allograft rejection.*Methods: Retrospective…
  • 2022 American Transplant Congress

    Health Care Transition of Adolescents After Kidney Transplantation in Germany and Austria – The Randomized Controlled Transnephro Trial

    L. Pape1, M. Kreuzer1, A. Großhenig2, J. Prüfe1, S. Group3

    1Pediatrics II, University Hospital of Essen, Essen, Germany, 2Biostatistics, Hannover Medical School, Hannover, Germany, 3German Society of Pediatric Nephrology, Berlin, Germany

    *Purpose: Adolescence is the age with the highest rate of graft losses because of non-adherence and the transfer from pediatric to adult care. Health care…
  • 2022 American Transplant Congress

    Impact of Donor Quality on Outcomes for AKI and Non-AKI Kidneys with and without DGF

    C. Jadlowiec1, P. Budhiraja2, R. Butterfield1, M. Smith3, A. K. Mathur1, A. Moss1, H. Khamash2, K. Reddy1, R. Heilman2

    1Mayo Clinic Arizona, Phoenix, AZ, 2Division of Transplant Nephrology, Mayo Clinic Arizona, Phoenix, AZ, 3Division of Anatomic Pathology, Mayo Clinic Arizona, Phoenix, AZ

    *Purpose: The relevance of DGF, and whether it is clinically significant, continues to be debated. Our aim was to compare post-transplant outcomes between AKI and…
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