2022 American Transplant Congress
Transitional-1 B Cell IL-10/TNFα Ratio Risk-Stratifies Renal Transplant Patients with Early Borderline Change
Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA
*Purpose: Recent studies have shown that Banff borderline change (BLC) on allograft biopsies (Bx) is associated with decreased graft survival. However, many patients with BLC…2022 American Transplant Congress
Efficacy and Safety of a Delayed Graft Function Protocol in Kidney Transplant Recipients
*Purpose: To evaluate the efficacy and safety of a protocol increasing the net state of immunosuppression for adult kidney transplant recipients (KTR) with delayed graft…2022 American Transplant Congress
Feasibility and Short-Term Outcomes of Kidney Transplantation Following Donation After Circulatory Death Using Thoracic Normothermic Regional Perfusion in the United States
Surgery, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Organ donation after circulatory death (DCD) is an important component of kidney transplants in the US. Cardiac transplantation from DCD donors has previously been…2022 American Transplant Congress
A Novel IL-2 Mutein Selectively Expands Regulatory T Cells and Prolongs Skin Graft Survival
*Purpose: Promoting immune regulation through expansion of regulatory T cell (Treg) may allow immunosuppression minimization and improve long-term graft outcomes. Low-dose IL-2 is known to…2022 American Transplant Congress
Month 1 Donor Derived Cell Free DNA Levels Predict Future Kidney Transplant Rejection
1Northwestern University, Chicago, IL, 2Transplant Nephrology, Northwestern University, Chicago, IL
*Purpose: The purpose of this study was to determine if donor-derived cell-free DNA (dd-cfDNA) can be used one-month post-transplant to predict later allograft rejection.*Methods: Retrospective…2022 American Transplant Congress
Liver Transplant Outcomes Using Grafts with Early Allograft Dysfunction
*Purpose: The significance of early allograft dysfunction (EAD) and its impact on liver transplant (LT) outcomes remains debated. Our study aimed to assess LT outcomes…2022 American Transplant Congress
Inferior Kidney Transplant Outcomes in Young Adults Transplanted as Children
UAB School of Medicine, Birmingham, AL
*Purpose: Adolescence (age 13-17 years) has been identified as a high-risk age interval for pediatric kidney transplant recipients, with accelerated rates of late acute rejection…2022 American Transplant Congress
Polarized Il-6 Secretion from Lymphatic Endothelial Cells Promotes Treg Conversion to Extregs
1University of Maryland School of Medicine, Baltimore, MD, 2University of Minnesota, Minneapolis, MN
*Purpose: Regulatory T cell (Treg) suppressor function and allograft protection depend on maintenance of transcription factor Foxp3 expression and lymphatic migration. Lymphatic endothelial cell (LEC)…2022 American Transplant Congress
Role of Urinary Biomarkers in RWE Clinical Paradigm
1Nephrosant, Brisbane, CA, 2NephroSant, Brisbane, CA
*Purpose: Due to heterogeneity observed in the kidney transplant population, it has been extremely challenging for traditional methods such as histopathology to predict graft outcomes.…2022 American Transplant Congress
Il-33 Induced Regulatory Macrophages Inhibit Transplantation Immune Rejection by Inducing Tregs
Beijing Chaoyang Hospital, Beijing, China
*Purpose: The occurrence of acute and chronic rejections after transplantation are key factors that affect the survival of the recipients. Induction of transplantation immune tolerance…
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