2022 American Transplant Congress
Hepatocyte SIRT1 Regulation of Apoptosis-Mediated Pyroptosis Cell Death in Mouse and Human Liver Transplantation
1UCLA Medical Center, Los Angeles, CA, 2NIEHS, Durham, NC
*Purpose: Cold static preservation is a gold-standard in orthotopic liver transplantation (OLT). However, the role of hepatocyte-specific SIRT1 transcriptional regulation of cell death programs during…2022 American Transplant Congress
Delayed Graft Function in Kidney Transplant Recipients is Associated with an Increased Risk f Post-Transplant Infections
*Purpose: Delayed graft function (DGF) is a known complication among kidney transplant recipients (KTRs) and is associated with decreased graft survival, increased rejection, and increased…2022 American Transplant Congress
Hard to Place Dual Kidney Transplantation (HTPDKT): A Viable Option Despite Prolonged Cold Ischemia
*Purpose: Less than perfect kidneys are often difficult to place in the current kidney allocation system. The kidneys have to travel extended distances , increasing…2022 American Transplant Congress
Solid Organ Pancreas Transplantation Offers Superior Glycemic Control Compared to State of the Art Insulin Delivery with Continuous Glucose Monitoring (CGM)
Columbia University, New York, NY
*Purpose: Advanced insulin delivery systems with CGM fail to keep serum glucose within range (70-180 mmol/L) 30-40% of the time resulting in Hgb A1C goals…2022 American Transplant Congress
Absolute Quantification of Donor-Derived Cell-Free DNA Does Not Provide Additional Discriminating Power Over Donor-derived Cell-Free DNA Fraction for Detection of Allograft Rejection
*Purpose: High level of background cell-free DNA (cfDNA) has been hypothesized as a concern for false negative results in molecular diagnostics for allograft rejection that…2022 American Transplant Congress
Cold Pulsatile Perfusion Preservation of Deceased Donor Kidneys Did Not Improve Delayed Graft Function Rates in Most Transplants Due to Longer Cold Ischemia Times Offsetting Much of the Benefit, Analysis of SRTR Database
Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL
*Purpose: To determine the impact of cold pulsatile perfusion preservation (CPPP) on delayed graft function (DGF) in a national cohort of US kidney transplants as…2022 American Transplant Congress
Impact of Maintaining Blood Pressure Goals on Graft Function After Kidney Transplant
Temple University Hospital, Philadelphia, PA
*Purpose: Impaired graft function following kidney transplant impacts short- and long-term patient outcomes. Proper management of systolic blood pressure (SBP) in the immediate post-operative period…2022 American Transplant Congress
Clinical Outcomes with IR-tac to LCP-tac Conversion in a Kidney Transplant Population
*Purpose: LCP-Tac is approved for conversion from IR-Tac in kidney transplant patients with a conversion rate of 70-80%. Studies have demonstrated similar efficacy and safety…2022 American Transplant Congress
Performance of Donor Derived Cell Free DNA (dd-cfDNA) in Diagnosing Subclinical and Clinical Acute Rejection in Kidney Transplant Recipients
*Purpose: The aim of this study was to examine the performance of Viracor TRAC donor derived cell free DNA (dd-cfDNA) in for-cause biopsies as well…2022 American Transplant Congress
Prediction of Delayed Graft Function After Deceased Donor Kidney Transplantation Using Machine Learning and Sequential Donor Data
*Purpose: Delayed graft function (DGF) has been associated with adverse kidney transplant outcomes. Accurate prediction of DGF before surgery will help select organs and candidates…
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