Articles tagged "Graft function"

2015 American Transplant Congress
Validating Outcomes Reported to the Organ Procurement and Transplantation Network for Deceased Donor Kidney Recipients
V. Potluri,¹ C. Parikh,² I. Hall,² J. Ficek,² M. Doshi,³ I. Butrymowicz,² F. Weng,⁴ B. Schröppel,⁵ H. Thiessen-Philbrook,⁶ P. Reese.⁷
¹Lankenau Hospital, Philadelphia; ²Yale University School of Medicine, New Haven; ³Wayne State University, Detroit; ⁴Barnabas Health, Livingston, NJ; ⁵University Hospital, Ulm, Germany; ⁶Western University, Ontario, Canada; ⁷University of Pennsylvania, Philadelphia.
Data reported to the Organ Procurement and Transplantation Network (OPTN) is used in kidney transplant research, quality metrics and in policy development, but the accuracy…
2015 American Transplant Congress
Fibrosis, Not Quantitative NGAL-Staining, in Day-10 Protocol Biopsies Predicts Prolonged Duration of Functional Delayed Graft Function in a Cohort of DCD Kidney Transplant Recipients
J. Bank,¹ M. Reinders,¹ M. Mallat,¹ N. Schlagwein,¹ S. van der Kooij,¹ D. van Gijlswijk,¹ I. Bajema,² C. van Kooten,¹ H. de Fijter.¹
¹Nephrology, LUMC, Leiden, Netherlands; ²Pathology, LUMC, Leiden, Netherlands.
Introduction: Extended criteria deceased kidneys are associated with prolonged delayed graft function and worse patient survival. Therefore it is important to identify factors in marginal…
2015 American Transplant Congress
Use of Tissue Plasminogen Activator (TPA) in Liver Transplantation from Donation After Cardiac Death (DCD) Donors: A Controlled Randomized Trial
B. Eghtesad, K. Hashimoto, M. Watson, M. Nazzal, C. Quintini, D. Kelly, T. Diago, N. Kawamura, G. El-Gazzaz, M. Fujiki, F. Aucejo, C. Winans, C. Miller, J. Fung.
Hepatobiliary and Liver Transplant Surgery, Cleveland Clinic, Cleveland, OH.
To further evaluate the impact of tPA in reduction of ITBS in livers recovered from the DCD donors we conducted a controlled randomized trial. Between…
2015 American Transplant Congress
hTERT, BICD1 and Chromosome 18 Polymorphisms Affecting Telomere Length Are Associated With Kidney Transplantation Outcome
L. Domanski,¹ K. Kloda,¹ K. Safranow,² A. Drozd,³ K. Ciechanowski,¹ A. Ciechanowicz.⁴
¹Clinical Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland; ²Department of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Szczecin, Poland; ³Department of Biochemistry and Human Nutrition, Pomeranian Medical University in Szczecin, Szczecin, Poland; ⁴Department of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Telomere length (TL) has been analyzed in regard to cell senescence and ageing of animals and humans, including age-related diseases. There have been also attempts…
2015 American Transplant Congress
Impact of Machine Perfusion After Long Static Cold Storage On Delayed Graft Function Incidence and Duration and Time to Hospital Discharge
A. Matos,¹ M. Borrelli, Jr.,¹ L. Moura Requiao,¹ M. Nogueira, Jr.,¹ L. Pertusier,¹ G. Clarizia,¹ P. Ongaro,¹ S. Ximenes,¹ M. Durao, Jr.,^1,2 A. Pacheco-Silva.^1,2
¹Transplantation, Hospital Israelita Albert Einstein, Sao Paulo, Brazil; ²Medicine/Nephrology, Escola Paulista de Medicina, UNIFESP, Sao Paulo, Brazil.
Our transplant center is not involved in organ harvesting and usually we receive a kidney for transplant with more then 20 hours of static cold…
2015 American Transplant Congress
Impact of Type of Tacrolimus Assay on Therapeutic Drug Monitoring: Need for Standardization
M. Singh, S. Anwar, D. Brennan, R. Delos Santos.
Internal Medicine/Nephrology, Washington University School of Medicine, St. Louis, MO.
Background: Multiple assays are available for measuring tacrolimus (FK) levels and these are not currently standardized. A designated laboratory transitioned their FK assay from Enzyme…
2015 American Transplant Congress
Operational Tolerance in Kidney Transplantation: Results of a Europe-Wide Survey
A. Massart,¹ A. Pallier,² O. Viklicky,^3,4 J. Pascual,^3,5 K. Budde,^3,6 S. Sorensen,^3,7 R. Oberbauer,^3,8 M. Klinger,^3,9 C. Dudley,^3,10 M. Sever,^3,11 G. Spasovski,^3,13 P. Guérif,² U. Maggiore,^3,12 M. Abramowicz,¹ M. Giral,² D. Abramowicz,¹⁴ S. Brouard.²
¹Erasme, Brussels, Belgium; ²Nantes University, Nantes, France; ³ERA-EDTA-DESCARTES Working Group, Parma, Italy; ⁴IKEM, Prague, Czech Republic; ⁵Hospital del Mar, Barcelona, Spain; ⁶CCM, Berlin, Germany; ⁷Rigshospitalet, Copenhagen, Denmark; ⁸KH Elisabethinen, Linz, Austria; ⁹WMU, Wrocław, Poland; ¹⁰NBT, Bristol, United Kingdom; ¹¹IMSSC, Istanbul, Turkey; ¹²Ospedale Maggiore, Parma, Italy; ¹³UCC, Skopje, Macedonia, The Former Yugoslav Republic of; ¹⁴UZA, Antwerpen, Belgium.
BACKGROUND: Operational Tolerance (opTOL) is deemed to be extremely rare in kidney transplantation. We launched a Europe-wide survey to assess the frequency of opTOL.METHODS: 18…
2015 American Transplant Congress
Impact of Cold Ischemic Time (CIT) and Distance Traveled (DT) on Shipped Kidneys in the OPTN/UNOS Kidney Paired Donation (KPD) Pilot Program (PP)
M. Aeder,¹ D. Stewart,² R. Leishman,² L. Robbins Callahan,² A. Kucheryavaya,² T. Sandholm,³ R. Formica.⁴
¹Univ Hosp Case Med Ctr, Cleveland, OH; ²UNOS, Richmond, VA; ³Carnegie Mellon Univ, Pittsburgh, PA; ⁴Yale Univ, New Haven, CT.
Background: The success of a national KPD program is predicated on excellent early kidney function and graft survival (GS). As other KPD programs have reported…