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Articles tagged "Graft function"

  • 2015 American Transplant Congress

    Transplantation of Kidneys from Donors With Acute Renal Failure: Five-Year Results from Double Center Experience

    C. Ramirez,1,2 A. Safra,1 A. Shah,1,2 C. Doria,1 W. Maley,1 A. Frank,1 C. Gorn,1 L. Lerner.2

    1Department of Surgery, Division of Transplantation, Thomas Jefferson University Hospital, Philadelphia, PA; 2Department of Kidney Transplantation, Lankenau Medical Center, Wynnewood, PA.

    Background: Transplantation of kidneys from deceased donors with acute renal failure (ARF) has been described and represents an underutilized source of renal grafts. We reviewed…
  • 2015 American Transplant Congress

    Validating Outcomes Reported to the Organ Procurement and Transplantation Network for Deceased Donor Kidney Recipients

    V. Potluri,1 C. Parikh,2 I. Hall,2 J. Ficek,2 M. Doshi,3 I. Butrymowicz,2 F. Weng,4 B. Schröppel,5 H. Thiessen-Philbrook,6 P. Reese.7

    1Lankenau Hospital, Philadelphia; 2Yale University School of Medicine, New Haven; 3Wayne State University, Detroit; 4Barnabas Health, Livingston, NJ; 5University Hospital, Ulm, Germany; 6Western University, Ontario, Canada; 7University of Pennsylvania, Philadelphia.

    Data reported to the Organ Procurement and Transplantation Network (OPTN) is used in kidney transplant research, quality metrics and in policy development, but the accuracy…
  • 2015 American Transplant Congress

    Fibrosis, Not Quantitative NGAL-Staining, in Day-10 Protocol Biopsies Predicts Prolonged Duration of Functional Delayed Graft Function in a Cohort of DCD Kidney Transplant Recipients

    J. Bank,1 M. Reinders,1 M. Mallat,1 N. Schlagwein,1 S. van der Kooij,1 D. van Gijlswijk,1 I. Bajema,2 C. van Kooten,1 H. de Fijter.1

    1Nephrology, LUMC, Leiden, Netherlands; 2Pathology, LUMC, Leiden, Netherlands.

    Introduction: Extended criteria deceased kidneys are associated with prolonged delayed graft function and worse patient survival. Therefore it is important to identify factors in marginal…
  • 2015 American Transplant Congress

    Impact of Cold Ischemic Time (CIT) and Distance Traveled (DT) on Shipped Kidneys in the OPTN/UNOS Kidney Paired Donation (KPD) Pilot Program (PP)

    M. Aeder,1 D. Stewart,2 R. Leishman,2 L. Robbins Callahan,2 A. Kucheryavaya,2 T. Sandholm,3 R. Formica.4

    1Univ Hosp Case Med Ctr, Cleveland, OH; 2UNOS, Richmond, VA; 3Carnegie Mellon Univ, Pittsburgh, PA; 4Yale Univ, New Haven, CT.

    Background: The success of a national KPD program is predicated on excellent early kidney function and graft survival (GS). As other KPD programs have reported…
  • 2015 American Transplant Congress

    hTERT, BICD1 and Chromosome 18 Polymorphisms Affecting Telomere Length Are Associated With Kidney Transplantation Outcome

    L. Domanski,1 K. Kloda,1 K. Safranow,2 A. Drozd,3 K. Ciechanowski,1 A. Ciechanowicz.4

    1Clinical Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland; 2Department of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Szczecin, Poland; 3Department of Biochemistry and Human Nutrition, Pomeranian Medical University in Szczecin, Szczecin, Poland; 4Department of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.

    Telomere length (TL) has been analyzed in regard to cell senescence and ageing of animals and humans, including age-related diseases. There have been also attempts…
  • 2015 American Transplant Congress

    Impact of Machine Perfusion After Long Static Cold Storage On Delayed Graft Function Incidence and Duration and Time to Hospital Discharge

    A. Matos,1 M. Borrelli, Jr.,1 L. Moura Requiao,1 M. Nogueira, Jr.,1 L. Pertusier,1 G. Clarizia,1 P. Ongaro,1 S. Ximenes,1 M. Durao, Jr.,1,2 A. Pacheco-Silva.1,2

    1Transplantation, Hospital Israelita Albert Einstein, Sao Paulo, Brazil; 2Medicine/Nephrology, Escola Paulista de Medicina, UNIFESP, Sao Paulo, Brazil.

    Our transplant center is not involved in organ harvesting and usually we receive a kidney for transplant with more then 20 hours of static cold…
  • 2015 American Transplant Congress

    Impact of Type of Tacrolimus Assay on Therapeutic Drug Monitoring: Need for Standardization

    M. Singh, S. Anwar, D. Brennan, R. Delos Santos.

    Internal Medicine/Nephrology, Washington University School of Medicine, St. Louis, MO.

    Background: Multiple assays are available for measuring tacrolimus (FK) levels and these are not currently standardized. A designated laboratory transitioned their FK assay from Enzyme…
  • 2015 American Transplant Congress

    Operational Tolerance in Kidney Transplantation: Results of a Europe-Wide Survey

    A. Massart,1 A. Pallier,2 O. Viklicky,3,4 J. Pascual,3,5 K. Budde,3,6 S. Sorensen,3,7 R. Oberbauer,3,8 M. Klinger,3,9 C. Dudley,3,10 M. Sever,3,11 G. Spasovski,3,13 P. Guérif,2 U. Maggiore,3,12 M. Abramowicz,1 M. Giral,2 D. Abramowicz,14 S. Brouard.2

    1Erasme, Brussels, Belgium; 2Nantes University, Nantes, France; 3ERA-EDTA-DESCARTES Working Group, Parma, Italy; 4IKEM, Prague, Czech Republic; 5Hospital del Mar, Barcelona, Spain; 6CCM, Berlin, Germany; 7Rigshospitalet, Copenhagen, Denmark; 8KH Elisabethinen, Linz, Austria; 9WMU, Wrocław, Poland; 10NBT, Bristol, United Kingdom; 11IMSSC, Istanbul, Turkey; 12Ospedale Maggiore, Parma, Italy; 13UCC, Skopje, Macedonia, The Former Yugoslav Republic of; 14UZA, Antwerpen, Belgium.

    BACKGROUND: Operational Tolerance (opTOL) is deemed to be extremely rare in kidney transplantation. We launched a Europe-wide survey to assess the frequency of opTOL.METHODS: 18…
  • 2015 American Transplant Congress

    Clinical and Pathologic Predictors of Response to Belatacept Conversion

    S. Patel, H. Morris, D. Cohen, S. Mohan, L. Ratner, R. Crew.

    Columbia Universtiy, New York.

    INTRO: Calcineurin inhibitors have improved kidney transplant and recipient survival, their use has significant nephrotoxicity. Belatacept is a recently approved immunosuppressant that is not nephrotoxic…
  • 2015 American Transplant Congress

    Transversal Observational Study On Recurrent and Late Urinary Tract Infections (UTIs) in Renal Transplantation (tx)

    G. Castellano,1 M. Fiorentino,1 M. Martino,1 M. Rossini,1 A. Schena,1 C. Manno,1 G. Grandaliano,2 P. Ditonno,3 M. Battaglia,3 L. Gesualdo.1

    1DETO, Nephrology, Dialysis and Transplantation Unit, University of Bari, Bari, Italy; 2Department of Medical and Surgical Sciences, Nephrology, Dialysis and Transplantation Unit, University of Foggia, Foggia, Italy; 3DETO, Andrology, Urology and Renal Transplantation Unit, University of Bari, Bari, Italy.

    UTIs are common complications after kidney tx. The aim of this study was to define the potential predisposing factors and the possible impact on graf…
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