Articles tagged "Graft function"

2015 American Transplant Congress
Eculizumab in the Treatment of Early Severe Acute Antibody Mediated Rejection Following HLA-Compatible Kidney Transplantation-Case Series
M. Singh,¹ N. Macias,² V. Tatapudi,¹ B. Lee.¹
¹Transplant Nephrology, UCSF Medical Center, San Francisco, CA; ²Nephrology, Hospital Gregorio Maranon, Madrid, Spain.
Severe early acute antibody-mediated rejection (AMR) is associated with poor allograft outcomes. Eculizumab is a humanized mouse monoclonal antibody against complement factor C5 that has…
2015 American Transplant Congress
Outcome of Kidney Transplantation from Older Living Donors: Histological Evaluation Using Zero-Time Biopsy Specimens
K. Omoto,¹ D. Toki,¹ M. Okumi,¹ T. Shimizu,¹ H. Ishida,¹ K. Honda,² J. Koike,³ K. Tanabe.¹
¹Department of Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan; ³Department of Pathology, St. Marianna University, School of Medicine, Kawasaki, Japan.
OBJECTIVE: The relationship between preimplantation biopsy and graft outcome in kidney transplantations from older living donors has not been studied yet. We reviewed graft outcomes…
2015 American Transplant Congress
Management of Pancreas Graft Splenic Vein Thrombosis: Is Conservative Management Safe?
J. Harbell,¹ T. Morgan,² V. Feldstein,² G. Roll,¹ A. Posselt,¹ S.-M. Kang,¹ S. Feng,¹ R. Hirose,¹ C. Freise,¹ P. Stock.¹
¹Surgery, University of California, San Francisco, San Francisco, CA; ²Radiology, University of California, San Francisco, San Francisco, CA.
Background: Prophylaxis for graft portal/splenic venous thrombosis following pancreas transplant varies between institutions. Similarly, treatment of venous thrombosis ranges from early re-exploration to conservative management…
2015 American Transplant Congress
Decline in Estimated Glomerular Filtration Rate and Subsequent Risk of Graft Failure and Mortality Among Kidney Transplant Recipients
P. Clayton,^1,2,3 W. Lim,^1,4 S. Chadban.^1,2,3
¹Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, Adelaide, Australia; ²Transplantation, Royal Prince Alfred Hospital, Sydney, Australia; ³Sydney Medical School, University of Sydney, Sydney, Australia; ⁴Department of Renal Medicine, Sir Charles Gairdner Hospital, Perth, Australia.
Purpose: Graft loss and death are generally late events after kidney transplantation, and trials designed to assess the impact of interventions on these outcomes are…
2015 American Transplant Congress
Biomarkers of Deceased Donors for the Prediction of Renal Allograft Outcomes
S. Kang,¹ H. Im,¹ J. Lee,¹ T. Koo,¹ S. Lee,² S. Park,³ S.-J. Kim,⁴ C. Ahn,¹ J. Yang.¹
¹Transplantation Center, Seoul National University Hospital, Seoul, Republic of Korea; ²Chonbuk National University Hospital, Jeonju, Republic of Korea; ³Inje University Busan Paik Hospital, Busan, Republic of Korea; ⁴Samsung Medical Center, Seoul, Republic of Korea.
Background: Better prognostic markers in deceased donors(DD) are needed for determining whether to accept suboptimal DD kidneys or predicting post-transplant outcomes. Recently, neutrophil gelatinase-associated lipocalin(NGAL),…
2015 American Transplant Congress
Longitudinal eGFR Modelling to Understand Rates of eGFR Decline in Renal Transplantation in the United Kingdom
R. Pruthi,¹ A. Casula,¹ R. Hilton,² R. Ravanan,³ P. Roderick,⁴ I. Macphee.⁵
¹UK Renal Registry, Bristol, United Kingdom; ²Guys Hospital, London, United Kingdom; ³Southmead Hospital, Bristol, United Kingdom; ⁴Southampton University, Southampton, United Kingdom; ⁵St Georges Hospital, London, United Kingdom.
Background: The rate of decline in eGFR (slope) has been independently associated with a higher risk of cardiovascular events and all cause mortality in kidney…
2015 American Transplant Congress
Early Weight Gain After Transplantation Can Cause Adverse Effect On Transplant Kidney Function
S. Choi, I.-K. Kim, S. Son, M. Ju.
Surgery, Gangnam Severance Hospital, Yonsei College of Medicine, Seoul, Korea.
Background: Outcomes of kidney transplant recipients with increased body mass index (BMI) remain controversial. We studied the relationship between change of BMI and transplant kidney…
2015 American Transplant Congress
Impact of Donor Hemoglobin A1c On Pancreas Graft Survival
K. Collins,¹ J. Garonzik-Wang,¹ E. King,² M. Doyle,¹ J. Lowell,¹ S. Shenoy,¹ Y. Lin,¹ J. Wellen,¹ W. Chapman,¹ D. Segev.²
¹Abdominal Transplant, Washington University, Saint Louis, MO; ²Surgery, Johns Hopkins University, Baltimore, MD.
A goal in selection of ideal donor pancreata is to avoid grafts with a predisposition to type-two diabetes. The HgA1c assay is a validated estimate…
2015 American Transplant Congress
Avoiding Futility in Simultaneous Liver-Kidney Transplantation (SLKT): Analysis of 331 Consecutively Listed Patients
K. Lunsford, A. Bodzin, D. Reino, A. Zarrinpar, F. Kaldas, H. Gritsch, J. Veale, G. Lipshutz, D. Farmer, G. Danovitch, H. Yersiz, J. Hiatt, R. Busuttil, V. Agopian.
Departments of Surgery, Urology, and Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Without well-established listing guidelines for SLKT, MELD prioritization of liver recipients with renal dysfunction potentially risks scarce renal allografts. We sought to evaluate short-term predictors…
2015 American Transplant Congress
Gender Differences in Kidney Transplant Delayed Graft Function Are Independent of Donor-Recpient Size Mismatch
M. Levine,¹ A. Thomasson,¹ D. Aufhauser,¹ R. Redfield,² P. Abt,¹ P. Reese.³
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Surgery, University of Wisconsin, Madison, WI; ³Medicine, University of Pennsylvania, Philadelphia, PA.
Introduction: Superior female tolerance of ischemia reperfusion injury (IRI) relative to males has been described in animal models, but little human data are available to…