2015 American Transplant Congress
Assessment of Renal Function in Kidney Transplant Recipients Through Therapeutic Drug Monitoring of Vancomycin
Massachusetts General Hospital, Boston, MA.
Background: Determining the dose of renally eliminated drugs such as vancomycin in kidney transplant recipients is often challenging due to unclear tools to assess renal…2015 American Transplant Congress
Inhibition of mTOR Modulates SLPI Expression: A Potential Role in Kidney Transplant Patients
Secretory leukocyte protease inhibitor (SLPI) is a serine protease inhibitor secreted by inflammatory and epithelial cells. It functions as an endogenous immunomodulatory, with antiinflammatory and…2015 American Transplant Congress
MicroRNA-21 (miR-21) Expression in Hypothermic Machine Perfusate May Predict Early Outcomes in Kidney Transplantation
Introduction: Hypothermic machine perfusion is effective in improving outcomes from kidney transplantation and molecular analyses of hypothermic machine perfusate (HMP) have the potential to identify…2015 American Transplant Congress
Normothermic Machine Perfusion (NMP) on Discarded Human Livers: The First Model in the US
Cleveland Clinic, Cleveland, OH.
The benefit of NMP preservation has been reported in a number of animal studies. Herein we describe safety, feasibility and effectiveness of NMP on discarded…2015 American Transplant Congress
Delayed Graft Function (DGF) in Kidney Transplant Recipients (KTRs) Is Associated With Early Allograft Inflammation and Progressive Fibrosis Within 3 Months
University of Pittsburgh, Pittsburgh.
DGF had been shown to be deleterious to KTR outcomes. Analysis of histological progression in KTRs with DGF was previously not attempted. In this prospective…2015 American Transplant Congress
A Preliminary Study of Using Small Intestinal Submucosa Scaffolds Coated Islets and Mesenchymal Stem Cells to Built Artificial Pancreas
Background: Although islet transplantation successful applied, shortage of donors, poor islet survival and toxicity of immunosuppressants often reduce the graft functional lifetime. Tissue engineered scaffold…2015 American Transplant Congress
The Association of Basiliximab and Antithymocyte Globulin Induction With Delayed Graft Function
The impact of selection of induction immunosuppression agent on incidence of delayed graft function (DGF) remains unclear. A total of 1,980 deceased donor kidney transplant…2015 American Transplant Congress
Donor Serum and Urine Proteomic Signatures Differentiate Between Immediate and Delayed Graft Function in Kidney Transplantation
IntroductionDespite the persistent shortage of donor organs, paradoxically, many organs obtained from older higher risk donors are deemed unsuitable for transplantation and discarded. The ability…2015 American Transplant Congress
Outpatient Management of Delayed Graft Function (DGF) Is Associated With Reduced Length of Stay and Acute Rejection
Delayed graft function (DGF) increases hospital length of stay (LOS) and risk for readmission, rejection, early graft loss and death. We created a multidisciplinary DGF…2015 American Transplant Congress
Post-Transplant Changes in Serum Creatinine and Beta-2 Microglobulin Predict Acute Tubular Necrosis in the Early Post-Transplant Period
Purpose: To evaluate the utility of early post-transplant changes in serum creatinine (SCr) and beta-2 microglobulin (B2M) in differentiating acute tubular necrosis (ATN) and other…
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