ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft function"

  • 2022 American Transplant Congress

    Impact of Varying Levels of Normal Range Baseline Donor Derived Cell Free DNA on Medium-Term Outcomes Following Kidney Transplantation

    K. K. Sureshkumar1, A. Grazier2, B. Chopra1

    1Nephrology, Medicine Institute, Allegheny General Hospital, Pittsburgh, PA, 2Abdominal Transplantation, Allegheny General Hospital, Pittsburgh, PA

    *Purpose: Donor derived cell free DNA (dd-cfDNA) is a biomarker with high negative predictive value for ruling out acute rejection (AR) in kidney allografts. Baseline…
  • 2022 American Transplant Congress

    Association Between Histopathological Features on Implantation Renal Biopsies and Graft Outcomes and Kdpi

    C. Khor, S. McGinn, C. Fisher, R. Yang, K. Richards, K. Muir, J. Lu

    Nephrology, Royal North Shore Hospital, Sydney, Australia

    *Purpose: The global shortage of organs and the increasing use of marginal kidneys for transplantation necessitates an accurate assessment of deceased donor kidneys. The kidney…
  • 2022 American Transplant Congress

    Donor Terminal Creatinine – Does It Matter?

    V. G. Menon, Y. Wert, W. Hoffman, D. Ladie, M. Singh, M. Waybill, H. Yang

    UPMC, Harrisburg, PA

    *Purpose: When assessing deceased donor kidneys, the transplantation team studies several donor variables including creatinine. A creatinine that is elevated immediately prior to procurement can…
  • 2022 American Transplant Congress

    Renal Function at Five Years from a Randomized Multicenter Trial of Belatacept-Based CNI Free and Early Steroid Withdrawal Immunosuppression

    E. Yanqui1, H. Hames1, A. R. Shields1, T. Shi1, A. L. Christianson1, J. Kremer2, A. Govil1, R. R. Alloway1, E. S. Woodle1

    1University of Cincinnati, Cincinnati, OH, 2Christ Hospital, Cincinnati, OH

    *Purpose: BENEFIT and BENEFIT EXT trials have demonstrated that belatacept-based immunosuppression was associated with improved long term renal allograft function compared to cyclosporine-based immunosuppression. Similar…
  • 2022 American Transplant Congress

    Conversion to Everolimus-Based Immunosuppression Regimen with Calcineurin Inhibitor Reduction Ameliorates Histological Damage in Kidney Transplant Recipients with Calcineurin Inhibitor-Induced Nephrotoxicity

    K. Hotta, N. Iwahara, T. Tanabe, N. Shinohara

    Hokkaido University Hospital, Sapporo, Japan

    *Purpose: In the last two decades, the short-term results for kidney transplantation (KTX) have improved owing to the use of calcineurin inhibitors (CNIs). However, long-term…
  • 2022 American Transplant Congress

    Baseline Levels and Early Post-Transplant Kinetics of Donor-Derived Cell-Free DNA Following Liver Transplantation

    S. Florman1, D. Axelrod2, J. Miles3, E. Vaskova3, D. Kilam3, K. Dhanireddy4, V. Subramanian4

    1Mount Sinai Medical Center, New York, NY, 2University of Iowa, Iowa City, IA, 3CareDx, South San Francisco, CA, 4Tampa General Hospital, Tampa, FL

    *Purpose: Non-invasive biomarkers in liver transplant (LT) are needed to improve detection of allograft injury in routine surveillance and during immunosuppression modulation, prior to the…
  • 2022 American Transplant Congress

    Anti-HLA Antibodies Do Not Increase in Kidney Transplant Recipients During COVID-19 Infection

    A. Girnita1, L. Wang1, P. Ahearn1, A. Colovai2, M. Fernandez-Vina1, E. Woodle3, T. Yalamarti1, M. Menon4, Y. Azzi2, M. Melcher1, R. Bray5, H. Gebel5, P. Cravedi4, J. Maltzman1, E. Akalin2

    1Stanford University, Palo Alto, CA, 2Albert Einstein College of Medicine, New York, NY, 3University of Cincinnati, Cincinnati, OH, 4Mount Sinai, New York, NY, 5Emory University Hospital, Atlanta, GA

    *Purpose: To determine if HLA allo-antibody levels are affected by COVID-19 in renal transplanted patients and to compare the immunoglobulin class and subclass profiles as…
  • 2022 American Transplant Congress

    Incidence of Delayed Graft Function in Kidneys Recovered After Normothermic Regional Perfusion

    L. James1, M. D'Angelo1, J. Carillo1, J. C. Berger1, D. E. Smith1, N. Moazami1, B. Lonze2

    1NYU Langone Health, New York, NY, 2NYU Langone Transplant Institute, New York, NY

    *Purpose: The use of normothermic reperfusion (NRP) following donation after circulatory death (DCD) is an emerging strategy for organ procurement. NRP technique reestablishes circulatory blood…
  • 2022 American Transplant Congress

    Belatacept Conversion in Proteinuric Kidney Transplant Recipients: Effects in a Prospective Trial and a Retrospective Cohort

    O. Efe1, A. Al Jurdi1, D. Wojciechowski2, K. Safa1, H. Gilligan1, A. Chandraker3, J. Azzi3, A. Weins3, L. V. Riella1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, 2UT Southwestern Medical Center, Dallas, TX, 3Brigham and Women's Hospital, Boston, MA

    *Purpose: Proteinuria after kidney transplantation is associated with worse allograft outcomes. B7-1 expression by podocytes has been linked to proteinuria by inducing podocyte migration which…
  • 2022 American Transplant Congress

    The Low Estimated Glomerular Filtration Rates at 6 and 12 Months After Living Kidney Transplantation Are Independent Risk for Graft Failure

    T. Hiramitsu1, T. Tomosugi2, K. Futamura2, O. Manabu1, N. Goto2, T. Ichimori2, S. Narumi2, Y. Watarai2

    1Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Myokencho Showaku, Japan, 2Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan

    *Purpose: The low estimated glomerular filtration rate (eGFR) at 1 year after kidney transplantation was demonstrated to be the risk for graft failure in the…
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