Articles tagged "Graft function"

2022 American Transplant Congress
De Novo Anti-Brush Border Antibody Disease in a Kidney Transplant Recipient
P. Yenebere, D. Ibrahim, T. Nadasdy, R. Daloul
Ohio State University, Columbus, OH
*Purpose: Anti-brush border antibody (ABBA) disease is very rare, characterized by tubulointerstitial damage caused by autoantibodies against LDL receptor-related protein 2 (LRP2) in the proximal…
2022 American Transplant Congress
Early Outcomes of Single Dose Eculizumab for Abo-Incompatible Living Donor Renal Transplantation
K. Heagler, M. Campara, P. Di Cocco, S. Gaitonde, I. Tang, J. Almario Alvarez, M. Spaggiari, J. Benken, C. S. Muran, B. Valdepenas, D. Pierce, I. Tzvetanov, E. Benedetti
UI Health, Chicago, IL
*Purpose: Use of ABO-incompatible (ABOi) donors increases access to living donor renal transplantation (LDRT). Conventional desensitization with plasmapheresis (PLEX) allows safe ABOi transplantation when pre-transplant…
2022 American Transplant Congress
Pump Resistance Thresholds and Graft Outcomes in Machine Perfused Kidneys-A Single Center Retrospective Study
S. Sivan, J. Gaynor, M. Tabbara, G. Ciancio
Univ of Miami Miller School of Medicine, Miami, FL
*Purpose: Perfusion parameters are increasingly used to assess the quality of organs and to make decisions about discarding the organ. Resistive index(RI) has been an…
2022 American Transplant Congress
The Effect of Late-Onset Cytomegalovirus Infection on the Outcome of Renal Allograft in Patients with Delayed Graft Function
M. Rahimi Shahmirzadi¹, M. Silverman¹, L. Gunaratnam², A. Jevnikar², A. A. House², S. Hosseini-Moghaddam³
¹Infectious Diseases Care Program, St. Joseph's Health Care London, London, ON, Canada, ²London Health Sciences Centre, London, ON, Canada, ³St. Joseph's Health Care London, London, ON, Canada
*Purpose: Delayed graft function (DGF) has been reported to increase the risk of renal allograft loss. The role of late-onset Cytomegalovirus infection in the association…
2022 American Transplant Congress
Evs from Patients with Amr Induce Tubular Senescence and Endmt Through Horizontal Transfer of Mirnas
R. Franzin¹, A. Stasi¹, F. Sallustio¹, S. Bruno², G. Merlotti³, M. Quaglia³, G. Grandaliano⁴, P. Pontrelli¹, J. Thurman⁵, G. Camussi², G. Stallone⁶, V. Cantaluppi³, L. Gesualdo¹, G. Castellano⁷
¹DETO, University of Bari, Bari, Italy, ²University of Turin, Turin, Italy, ³University of Piemonte Orientale, Novara, Italy, ⁴Università Cattolica Sacro Cuore, Rome, Italy, ⁵University of Colorado School of Medicine, Aurora, CO, ⁶University of Foggia, Foggia, Italy, ⁷University of Milan, Milan, Italy
*Purpose: Extracellular vesicles (EV) are emerging mediators in several diseases; however, their role in antibody-mediated allograft rejection (AMR) has been poorly investigated.*Methods: Plasma EVs from…
2022 American Transplant Congress
Discovery of Risk Factor Control Targets Using Machine Learning and Network Analysis for One-Year Renal Allograft Dysfunction
Y. Lee¹, M. Hong², J. Kong³, O. Kwon⁴, C. Jung⁵, J. Yang⁶, M. Kim⁷, H. Han⁸, S. Nam⁹
¹Division of Nephrology, Department of Internal medicine, CHA Bundang Medical Center, Seongnam, Korea, Republic of, ²Department of Biomedical Informatics,, CHA University School of Medicine, Seongnam, Korea, Republic of, ³Department of Nephrology,, BHS Hanseo Hospital, Pusan, Korea, Republic of, ⁴Department of Surgery, College of Medicine, Han Yang University, Seoul, Korea, Republic of, ⁵Department of Surgery, Korea University Anam Hospital, Seoul, Korea, Republic of, ⁶Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of, ⁷Department of Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of, ⁸Department of Biomedical Informatics, CHA University School of Medicine, CHA University, Seongnam, Korea, Republic of, ⁹Department of Ophthalmology, CHA Bundang Medical Center, Seongnam, Korea, Republic of
*Purpose: Early identification of graft loss risk and timely therapeutic intervention are crucial for preventing late renal allograft failure and improving long-term graft function. This…
2022 American Transplant Congress
The Impact of Donor’s Metabolic Syndrome Factor on Living Kidney Transplantation
Y. Miyauchi, T. Noda, N. Miura, T. Kikugawa, T. Saika
Ehime University, Toon, Japan
*Purpose: Because donors for kidney transplantation are also aging in Japan, it is not uncommon that donors have metabolic syndrome (Met-S). It is necessary to…
2022 American Transplant Congress
Impact of Early Corticosteroid Withdrawal on Simultaneous Pancreas-Kidney Transplant Long-Term Outcomes: Single Center Experience and Comparison to the International Pancreas Transplant Registry
D. Pierce¹, A. Lichvar², A. Gruessner³, I. Tang¹, P. DiCocco¹, M. Spaggiari¹, I. Tzvetanov⁴, E. Benedetti¹, M. Campara¹
¹University of Illinois at Chicago, Chicago, IL, ²University of California San Diego Health, San Diego, CA, ³SUNY Downstate Medical Center, Brooklyn, NY, ⁴University of Illinios at Chicago, Chicago, IL
*Purpose: The purpose of this study is to assess the long-term efficacy and safety of early corticosteroid withdrawal (ESW) compared to corticosteroid maintenance (CCS) immunosuppression…
2022 American Transplant Congress
Lipid Metabolism Profile of Human Kidneys During Ex Vivo Normothermic Perfusion
J. Yu, I. Palma, S. Adams, J. Sageshima, P. Than, R. Perez
UC Davis Medical Center, Sacramento, CA
*Purpose: The kidney is a highly metabolic organ and lipids are an important energy source. In this study, we examined the lipid profiles of discarded…
2022 American Transplant Congress
DCD and AKI Kidneys Experiencing DGF as a Platform for the Study of Adaptive Repair
B. Bussolati¹, S. Da Sacco², A. Asthana³, L. N. Byers³, L. Perin⁴, M. S. Garner³, B. Sharda³, A. C. Farney³, C. J. Jay³, R. J. Stratta³, S. J. Walker⁵, G. Orlando³
¹University of Turin, Turin, Italy, ²Children Hospital Los Angeles, Los Angeles, NC, ³Wake Forest Baptist Medical Center, Winston-Salem, NC, ⁴Children Hospital Los Angeles, Los Angeles, CA, ⁵WFIRM, Winston-Salem, NC
*Purpose: AKI and DCD renal allografts are at high risk for DGF, yet the majority of these kidneys will eventually recover and attain good function…

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