ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft function"

  • 2017 American Transplant Congress

    IP-10 Monoclonal Antibody Treatment Suppresses Inflammatory Components of IBMIR and Improves Pancreatic Islet Graft Function.

    G. Yoshimatsu,1 C. Chang,1 C. Darden,1 P. Saravanan,1 B. Naziruddin,2 M. Lawrence.1

    1Baylor Scott and White Reseasrch Institute, Dallas, TX; 2Baylor Simmons Transplant Institute, Dallas, TX

    Introduction: An instant blood-mediated inflammatory response (IBMIR) causes acute loss of pancreatic islets. Interferon gamma-induced protein 10 (IP-10) is a key proinflammatory chemokine that may…
  • 2017 American Transplant Congress

    Analysis of Differences in Living Donor and Recipient Pairs Estimated GFR at Six Months Over Time.

    D. Keith.

    Medicine, Division of Nephrology, Sacred Heart Hospital, Pensacola, FL

    Previous studies of the United States Kidney Transplant Database revealed that the median estimated GFR (eGFR) has improved over the last decade for living donor…
  • 2017 American Transplant Congress

    Orthotopic Liver Transplantation of Xenogeneic Livers Repopulated with Autologous Hepatocytes: Proof of Normal Function and Consistent Survival.

    G. Oldani, S. Lacotte, L. Orci, V. Delaune, C. Toso.

    Geneva University Hospitals, Geneva, Switzerland

    BackgroundGeneration of transplantable patient-like organs in pigs will solve the problem of organ shortage and potentially extend the indications for liver transplantation. However, the efficacy…
  • 2017 American Transplant Congress

    Outcome of Systemic Monitoring of DSA and Protocol Management to Optimize Renal Allograft Outcome in a Single Transplant Center.

    S. Chang,1 I. Mallawaarachchi,2 C. Yip,1 T. Shanahan,3 A. Gundroo,1 A. Dwivedi,2 S. Patel,4 M. Zachariah.1

    1Internal Medicine, University of Buffalo, Buffalo, NY; 2Biomedical Sciences, Texas Tech University, El Paso, TX; 3IMMCO Diagnostics, Buffalo, NY; 4Surgery, University of Buffalo, Buffalo, NY

    Denovo (dn) donor specific antibody (DSA) development has been shown to adversely affect long-term allograft survival. To improve graft outcome for kidney (K) transplant (Tx)…
  • 2017 American Transplant Congress

    Prolonged Cold Ischemia Time as a Risk for Low Regeneration at the Early Phase After Living Donor Liver Transplantation.

    K. Takahashi,1,2 S. Nagai,1 M. Safwan,1 K. Putchakayala,1 M. Rizzari,1 K. Collins,1 A. Yoshida,1 G. Schnickel,1 M. Abouljoud.1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 2Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan

    Background. The objective of this study was to determine the risk factors for low liver regeneration at the early phase after living donor liver transplantation…
  • 2017 American Transplant Congress

    Noninvasive Renal Transplant Graft Monitoring in Single Institution Using Cell-Free DNA in Recipient Plasma via Insertion-Deletion Allele Polymorphism.

    Y. Goh,1 S. Ho,2 L. Raman,1 V. Anantharaman,3 T. Goh,3 S. Koay,2 H. Tiong.1

    1Urology, National University Hospital, Singapore, Singapore; 2Laboratory Medicine, National University Hospital, Singapore, Singapore; 3Nephrology, National University Hospital, Singapore, Singapore

    IntroductionThere is an unmet clinical need in renal transplantation towards early detection of donor organ damage. Serum creatinine(SCr) and biopsies are not ideal.Cell-free donor DNA(cfdDNA)…
  • 2017 American Transplant Congress

    Is “Death with a Functioning Graft (DWF)” Really Death with Function? Data from the Long-Term Deterioration of Kidney Allograft Function (DeKAF) Study.

    R. Gaston,1 A. Fieberg,2 L. Hunsicker,3 D. Rush,4 R. Leduc,2 J. Connett,2 A. Matas,2 DeKaf Investigators.

    1UAB, Birmingham, AL; 2U Minnesota, Minneapolis, MN; 3U Iowa, Iowa City, IA; 4U Manitoba, Winnipeg, Canada

    To understand causes of kidney transplant (KT) failure, outcomes are often segregated into death-censored graft failure (DCGF, a proxy for immunologic injury) and DWF. To…
  • 2017 American Transplant Congress

    Delayed Graft Function[mdash]Less Ominous for ARF or DCD Recipients?

    M. Barrett, A. Smith, K. Woodside, R. Sung.

    University of Michigan, Ann Arbor

    Delayed Graft Function (DGF) is both a transplant outcome and risk factor for graft failure. Kidneys from donors with kidney injury--such as acute renal failure…
  • 2017 American Transplant Congress

    Risk of Kidney Rejection Following Simultaneous Liver Kidney Transplantation.

    S. Shah,1 A. Suddle,1 V. Aluvihare,1 O. Shaw,3 C. Shaw,1 N. Mamode,2 C. Callaghan,2 G. Koffman,2 N. Heaton.1

    1King's College Hospital, London, United Kingdom; 2Guy's and St Thomas' Hospital, London, United Kingdom; 3Viapath, London, United Kingdom

    Introduction: Simultaneous liver kidney transplant (SLK) recipients may be at risk of antibody-mediated kidney rejection (AMR) if the pre-transplant crossmatch is positive (+CXM). Accordingly, in…
  • 2017 American Transplant Congress

    Long-Term Pediatric Live-Donor Liver Transplantation Survivors: Patient and Allograft Outcomes.

    N. Celik,1 A. Ganoza,1 G. Bond,1 K. Soltys,1 R. Sindhi,1 P. McKiernan,3 A. Humar,2 G. Mazariegos.1

    1Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Thomas E. Starzl Transplantation Institute, Pittsburgh, PA; 3Division of Pediatric Gastroenterology, Pittsburgh, PA

    Aim: To determine the patient and allograft outcomes at 5 years after pediatric live-donor liver transplantation (LDLT).Methods: Children with a minimum of 5-year survival post-transplantation…
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