Articles tagged "Graft function"

2022 American Transplant Congress
Real-Time Application of Deep Learning in Diagnosis of Graft Fibrosis After Liver Transplantation Using Longitudinal Data
A. Azhie¹, D. Sharma², P. Sheth¹, W. Xu³, M. Bhat¹
¹Ajmera Transplant Program, University Health Network, Toronto, ON, Canada, ²Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada, ³Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
*Purpose: Graft fibrosis develops insidiously in liver transplant recipients and is associated with worse survival. Early detection of fibrosis is essential to avoid further progression…
2022 American Transplant Congress
Treading the Paradigm Shift: A Single Center Comparative Study of Outcomes Between Pre-Emptive and Early Kidney Transplant with Non Pre-Emptive Kidney Transplant Recipients Innational Kidney and Transplant Institute
E. U. Go, L. Baloloy
Organ Transplantation and Vascular Surgery, National Kidney and Transplant Institute, Quezon City, Philippines
*Purpose: To compare the 3-year outcome of pre-emptive and early kidney transplant recipients versus non pre-emptive recipients in our institution from January 2013 to December…
2022 American Transplant Congress
Early Outcomes Since Implementation of New Kidney Allocation System
K. Shah, F. Siddiqui, P. N. Chotai, A. Logan, A. Schenk, K. Washburn, A. Limkemann
Comprehensive Transplant Center, The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: The new Kidney allocation system (nKAS) implemented for optimization of organ placement. Like other organ allocation systems, kidney has been redefined from donation service…
2022 American Transplant Congress
Impact of Low Dose Donor-Specific HLA Antibodies in Living and Deceased Donor Kidney Transplantation
H. Lee¹, I. Sun², C. Yang¹, B. Chung¹
¹Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's hospital, Seoul, Korea, Republic of, ²Division of Nephrology, Department of Internal Medicine., Presbyterian Medical Center, Jeonju, Korea, Republic of
*Purpose: The prognostic value of low level preformed donor-specific antibodies (DSA) remains controversial for kidney transplantation. The aim of the present study was to investigate…
2022 American Transplant Congress
Hepatocyte SIRT1 Regulation of Apoptosis-Mediated Pyroptosis Cell Death in Mouse and Human Liver Transplantation
K. Kadono¹, H. Hirao¹, H. Kojima¹, K. J. Dery¹, X. Li², J. Kupiec-Weglinski¹
¹UCLA Medical Center, Los Angeles, CA, ²NIEHS, Durham, NC
*Purpose: Cold static preservation is a gold-standard in orthotopic liver transplantation (OLT). However, the role of hepatocyte-specific SIRT1 transcriptional regulation of cell death programs during…
2022 American Transplant Congress
Delayed Graft Function in Kidney Transplant Recipients is Associated with an Increased Risk f Post-Transplant Infections
V. Manchala, B. Muth, E. Yousif, J. Turk, J. Blazel, M. Bloom, N. Garg, F. Aziz, M. Mohamed, A. Djamali, D. Mandelbrot, B. Astor, S. Parajuli
UWSMPH, Madison, WI
*Purpose: Delayed graft function (DGF) is a known complication among kidney transplant recipients (KTRs) and is associated with decreased graft survival, increased rejection, and increased…
2022 American Transplant Congress
Hard to Place Dual Kidney Transplantation (HTPDKT): A Viable Option Despite Prolonged Cold Ischemia
R. Plews¹, E. Siskind², M. Laftavi², E. Shipman³, S. Shah², D. Conti⁴, A. Adekile², S. Nijim², S. K. Patel²
¹Albany Medical College, Albany, NY, ²Center for Transplantation, University Medical Center of Southern Nevada, Las Vegas, NV, ³Nevada Donor Network, Las Vegas, NV, ⁴Albany Medical Center, Albany, NY
*Purpose: Less than perfect kidneys are often difficult to place in the current kidney allocation system. The kidneys have to travel extended distances , increasing…
2022 American Transplant Congress
Solid Organ Pancreas Transplantation Offers Superior Glycemic Control Compared to State of the Art Insulin Delivery with Continuous Glucose Monitoring (CGM)
K. R. McCune, G. K. Dube, P. R. Sandoval, L. E. Ratner
Columbia University, New York, NY
*Purpose: Advanced insulin delivery systems with CGM fail to keep serum glucose within range (70-180 mmol/L) 30-40% of the time resulting in Hgb A1C goals…
2022 American Transplant Congress
Absolute Quantification of Donor-Derived Cell-Free DNA Does Not Provide Additional Discriminating Power Over Donor-derived Cell-Free DNA Fraction for Detection of Allograft Rejection
R. Gohh¹, S. Jordan², R. N. Woodward³, K. M. Clark-Langone³, J. Morlan³, B. Silva³, M. Weir⁴
¹Alpert School of Medicine Brown University, Providence, RI, ²Cedars Sinai Medical Ctr, Los Angeles, CA, ³CareDx, Redwood City, CA, ⁴University of Maryland School of Medicine, Baltimore, MD
*Purpose: High level of background cell-free DNA (cfDNA) has been hypothesized as a concern for false negative results in molecular diagnostics for allograft rejection that…
2022 American Transplant Congress
Cold Pulsatile Perfusion Preservation of Deceased Donor Kidneys Did Not Improve Delayed Graft Function Rates in Most Transplants Due to Longer Cold Ischemia Times Offsetting Much of the Benefit, Analysis of SRTR Database
D. S. Keith, E. Lessmann
Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL
*Purpose: To determine the impact of cold pulsatile perfusion preservation (CPPP) on delayed graft function (DGF) in a national cohort of US kidney transplants as…