Articles tagged "Graft function"

2019 American Transplant Congress
Protective Effect of Ischemic-Free Liver Transplantation Technique on Distant Multiple Organ Function
L. Wang¹, Z. Guo¹, L. Yang², W. Xiong², S. Huang¹, T. Zhang², Y. Tang¹, Z. Zhang¹, Z. Zhu¹, C. Zhu¹, X. He¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Anesthesiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Hypothermia, hypoxia and ischemia-reperfusion injury (IRI) in standard liver transplantation (SLT) are the main factors that affect graft function and cause damage to remote…
2019 American Transplant Congress
Prevention of Graft Ischemia-Reperfusion Injury in Ischemia-Free Liver Transplantation
Z. Guo, X. He, Q. Zhao, S. Huang, Z. Zhang, L. Wang, W. Ju, G. Chen
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Graft ischemia-reperfusion injury (IRI) is an inevitable event in organ transplantation, which often leads to a number of complications and even patient deaths. We…
2019 American Transplant Congress
Differences of Gut Microbiota Composition between Donor and Recipient May Predict 1-Year Graft Function
J. Kim¹, H. Cho², J. Park³, J. Jeong¹, M. Kwak⁴, B. Kim⁴, D. Kim¹, J. Lee⁵, B. Kim⁶, Y. Kim¹, H. Lee¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Chungbuk National University Hospital, Cheongju, Korea, Republic of, ³Kangwon National University Hospital, Seoul, Korea, Republic of, ⁴Chunlab Inc., Seoul, Korea, Republic of, ⁵Seoul National University Boramae Hospital, Seoul, Korea, Republic of, ⁶Hallym University, Chuncheon, Korea, Republic of
*Purpose: Signals derived from gut microbiota are critical for the development and maintenance of the human immune system. In view of kidney transplantation (KT), allograft…
2019 American Transplant Congress
Illustration of Renal Recovery in SLK with Utilization of Most Recent Allocation Criteria
B. Patel, R. Prashar, A. Babu
Henry Ford Hospital Detroit, Detroit, MI
*Purpose: Single Center review of Renal recovery in Simultaneous Liver Kidney Transplantation (SLKT) in patients who were approved for SLK based on the recent UNOS…
2019 American Transplant Congress
The Predictive Value Of Pre-transplant Biopsies For Short-term And Long-term Graft Function In Kidney Transplantation
H. Zhang¹, L. Liu¹, S. Yang², W. Chen², X. Chen¹, Y. Li², C. Wang¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: The predictive capacity of previous pre-transplant histologic scoring systems for short-term and long-term graft function in kidney transplantation has not been adequately validated.*Methods: Deceased…
2019 American Transplant Congress
Comparison of Oral Microbiome in Stable vs Declining Kidney Function in Renal Transplant Recipients
J. Wu¹, A. Muthusamy², G. Al-Ghalith³, B. Wu⁴, B. Guo⁴, W. Guan⁴, D. Knights³, W. Oetting⁵, D. Schladt², R. Remmel⁵, P. Jacobson⁵, A. K. Sharma⁶, A. Matas⁷, A. Israni¹, D. Skaar⁸
¹Nephrology, Hennepin Healthcare, Minneapolis, MN, ²Hennepin Health Research Institute, Minneapolis, MN, ³Computer Science, University of Minnesota, Minneapolis, MN, ⁴Biostatistics, University of Minnesota, Minneapolis, MN, ⁵Pharmacy, University of Minnesota, Minneapolis, MN, ⁶Animal Science, University of Minnesota, Minneapolis, MN, ⁷Surgery, University of Minnesota, Minneapolis, MN, ⁸Denistry, University of Minnesota, Minneapolis, MN
*Purpose: Transplantation causes dysbiosis of the oral microbiome of renal transplant recipients and has been correlated with worse allograft outcomes. We hypothesize that there are…
2019 American Transplant Congress
Impact of T-cell Mediated Allograft Rejection and Antibody Mediated Rejection within the First Year after Kidney Transplantation
I. Owoyemi, D. Jorgensen, S. Tandukar, R. Mehta, S. Hariharan
Thomas E. Starzl Institute of Transplantation and Division of Transplant Nephrology, UPMC, Pittsburgh, PA
*Purpose: This study evaluated the impact of Clinical and Sub-clinical T-Cell-Mediated Rejection (TCMR), Sub-Clinical Inflammation and Antibody Mediated Rejection (ABMR) within the 1st year post-kidney…
2019 American Transplant Congress
Predicting Metabolic Outcomes in Islet Autotransplantation before Transplantation
M. A. Kanak, P. Saravanan, J. Kalivarathan, Y. Shindo, M. F. Levy
Virginia Commonwealth University, Richmond, VA
*Purpose: Total Pancreatectomy with Islet Auto-transplantation (TPIAT) has been actively performed on patients with severe, debilitating pain of chronic pancreatitis. The outcome of islet transplantation…
2019 American Transplant Congress
Minimizing Kidney Ischemia Reperfusion Injury by Transferring Exogenous Mitochondria
A. Bajwa¹, V. Bontha¹, J. Eason², D. Maluf³, V. Mas⁴
¹UT, Memphis, TN, ²Director of Transplant Institute. UTHSC, Memphis, TN, ³UTHSC, Memphis, TN, ⁴Director of Transplant Research Institute. UTHSC, Memphis, TN
*Purpose: Ischemia induces altered bioenergetics with increased mitochondrial swelling and reactive oxygen species (ROS) and ultimately degradation of cellular function. Ischemia followed by reperfusion (IRI)…
2019 American Transplant Congress
Organ Resilience Contributes to Different Impact of Delayed Graft Function (DGF) on Graft Survival in Kidneys Donated by Brain Death (DBD) and Circulatory Death Donors (DCD)
M. J. de Kok, A. F. Schaapherder, L. G. Wijermars, D. K. de Vries, J. L. Lindeman
Transplantation Center, LUMC, Leiden, Netherlands
*Purpose: Despite a tripled higher incidence of DGF in DCD kidney grafts compared to DBD kidney grafts, large studies show equivalent long-term graft survival with…