Articles tagged "Graft function"

2022 American Transplant Congress
Anti-HLA Antibodies Do Not Increase in Kidney Transplant Recipients During COVID-19 Infection
A. Girnita¹, L. Wang¹, P. Ahearn¹, A. Colovai², M. Fernandez-Vina¹, E. Woodle³, T. Yalamarti¹, M. Menon⁴, Y. Azzi², M. Melcher¹, R. Bray⁵, H. Gebel⁵, P. Cravedi⁴, J. Maltzman¹, E. Akalin²
¹Stanford University, Palo Alto, CA, ²Albert Einstein College of Medicine, New York, NY, ³University of Cincinnati, Cincinnati, OH, ⁴Mount Sinai, New York, NY, ⁵Emory University Hospital, Atlanta, GA
*Purpose: To determine if HLA allo-antibody levels are affected by COVID-19 in renal transplanted patients and to compare the immunoglobulin class and subclass profiles as…
2022 American Transplant Congress
Incidence of Delayed Graft Function in Kidneys Recovered After Normothermic Regional Perfusion
L. James¹, M. D'Angelo¹, J. Carillo¹, J. C. Berger¹, D. E. Smith¹, N. Moazami¹, B. Lonze²
¹NYU Langone Health, New York, NY, ²NYU Langone Transplant Institute, New York, NY
*Purpose: The use of normothermic reperfusion (NRP) following donation after circulatory death (DCD) is an emerging strategy for organ procurement. NRP technique reestablishes circulatory blood…
2022 American Transplant Congress
Belatacept Conversion in Proteinuric Kidney Transplant Recipients: Effects in a Prospective Trial and a Retrospective Cohort
O. Efe¹, A. Al Jurdi¹, D. Wojciechowski², K. Safa¹, H. Gilligan¹, A. Chandraker³, J. Azzi³, A. Weins³, L. V. Riella¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, ²UT Southwestern Medical Center, Dallas, TX, ³Brigham and Women's Hospital, Boston, MA
*Purpose: Proteinuria after kidney transplantation is associated with worse allograft outcomes. B7-1 expression by podocytes has been linked to proteinuria by inducing podocyte migration which…
2022 American Transplant Congress
The Low Estimated Glomerular Filtration Rates at 6 and 12 Months After Living Kidney Transplantation Are Independent Risk for Graft Failure
T. Hiramitsu¹, T. Tomosugi², K. Futamura², O. Manabu¹, N. Goto², T. Ichimori², S. Narumi², Y. Watarai²
¹Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Myokencho Showaku, Japan, ²Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan
*Purpose: The low estimated glomerular filtration rate (eGFR) at 1 year after kidney transplantation was demonstrated to be the risk for graft failure in the…
2022 American Transplant Congress
The Effect of Baseline Blood Pressure on Early Graft Function in Deceased Donor Kidney Transplantation
B. Jun Bae¹, C. Oh¹, H. Ahn²
¹Department of surgery, Ajou University Medical School, Suwon, Korea, Republic of, ²Department of Anesthesiology and Pain medicine, Ajou University Medical School, Suwon, Korea, Republic of
*Purpose: The adequate perfusion pressure to the graft is essential for proper graft function in kidney transplantation, especially in deceased donor kidney transplantation. Therefore, the…
2022 American Transplant Congress
Donor Organ Utilization And Transplantation Outcomes In Donation After Circulatory Death Using Thoracoabdominal Normothermic Regional Perfusion
M. Urban, S. Merani, N. W. Markin, A. Castleberry, J. Um
University of Nebraska Medical Center, Omaha, NE
*Purpose: Evidence suggests that in-situ reperfusion of abdominal organs with normothermic oxygenated blood in donation after circulatory death (DCD) provides superior post-transplantation outcomes in comparison…
2022 American Transplant Congress
Use of New 2021 CKD-EPI as an Endpoint in Transplant Trials May Significantly Influence Observations
E. Yanqui¹, H. Hames¹, T. Shi², A. R. Shields¹, E. S. Woodle¹, R. R. Alloway¹
¹University of Cincinnati, Cincinnati, OH, ²CCHMC, Cincinnati, OH
*Purpose: GFR equations have recently been modified primarily to avoid disadvantaging black populations. The purpose of this study was to evaluate renal function and the…
2022 American Transplant Congress
A Pilot Study Using Registry-Based External Controls for the Cyclosporine Arm of the BENEFIT Study
A. Klein¹, D. Stewart², A. Toll², W. E. Fitzsimmons¹
¹Transplant Therapeutics Consortium, Critical Path Institute, Tucson, AZ, ²UNOS, Richmond, VA
*Purpose: The Transplant Therapeutics Consortium established a real-world evidence workgroup evaluating the potential of supplementing internal control arms with external controls to understand the impact…
2022 American Transplant Congress
Early Detection of Acute Rejection by Urine QSant is Not Confounded by Post-Transplant Time
C. Baan¹, S. Ghosh², J. Verhoeven¹, D. Hesselink¹, K. Boer¹, M. Sarwal²
¹Erasmus MC, Rotterdam, Netherlands, ²NephroSant, Brisbane, CA
*Purpose: We explore the viability of urinary biomarker-based monitoring for rejection in early days following renal transplantation.*Methods: Patients are from the Erasmus MC and received…
2022 American Transplant Congress
Delayed Graft Function in Living Donor Kidney Transplantation: Risk Factors and Outcomes
G. Defelice¹, A. Paramesh², H. Jeon², K. Atiemo², M. Killackey², A. Vijay²
¹Tulane University School of Medicine, New Orleans, LA, ²Transplant Surgery, Tulane University School of Medicine, New Orleans, LA
*Purpose: Delayed graft function (DGF) following living donor kidney transplantation is less common and long-term outcomes are less understood. This single-center retrospective analysis of living…