Articles tagged "Graft function"

2020 American Transplant Congress
Effect of Everolimus and Reduced Calcineurin Inhibitors on Biopsy Proven BK Virus Associated Nephropathy
Z. S. Zaky, M. Spinner, B. Stephany, S. Nurko, R. Fatica, J. Augustine, E. Poggio
Cleveland Clinic, Cleveland, OH
*Purpose: BK virus-associated nephropathy (BKVAN) is a clinically important entity that contributes to allograft loss in kidney transplant recipients (KTRs). Mammalian target of rapamycin inhibitors…
2020 American Transplant Congress
Persistent Tertiary Hyperparathyroidism in the First Year after Kidney Transplantation is Associated with Calcium Phosphate Deposition in the Kidney Allograft
R. S. Avasare¹, N. K. Andeen², M. Stack¹, E. N. Dewey³, S. Rehman¹, M. Shindo⁴, J. Y. Lim³
¹Nephrology & Hypertension, OHSU, Portland, OR, ²Pathology, OHSU, Portland, OR, ³Surgery, OHSU, Portland, OR, ⁴Otolaryngology, OHSU, Portland, OR
*Purpose: To investigate risk factors for calcium phosphate deposition in the kidney allograft.*Methods: This is a single-institution, retrospective analysis of adult patients who underwent kidney…
2020 American Transplant Congress
Peritoneal Dialysis in Delayed Graft Function, a Safe and Effective Option
A. Gardezi, B. Muth, F. Aziz, N. Garg, M. Mohamed, A. Djamali, D. Mandelbrot, S. Parajuli
University of Wisconsin, Madison, WI
*Purpose: Peritoneal dialysis (PD) has been utilized increasingly in the past decade. Many of these patients undergo transplantation and may require dialysis for delayed graft…
2020 American Transplant Congress
Artificial Intelligence May Detect Donor Liver Steatosis and Predict Early Post-Transplantation Graft Failure
R. R. Narayan, L. Yang, N. Abadilla, S. B. Chen, J. P. Higgins, M. L. Melcher
Stanford University, Stanford, CA
*Purpose: To compare the accuracy of donor liver biopsy slides scored by manual histopathologic review versus a computer vision artificial intelligence (CVAI) platform to predict…
2020 American Transplant Congress
Outcomes of High KDPI Kidneys in Selected Recipients at a Large Center
J. Pagan, L. Preczewski, M. Muldoon, L. Mendez, A. Harshman, E. Shipman, G. Guerra
Miami Transplant Institute, Miami, FL
*Purpose: Kidneys from donors with high KDPI’s are frequently discarded due to concerns about short- and long-term outcomes. Despite the decreased graft survival of these…
2020 American Transplant Congress
BK Viremia: A Double Edged Sword – The Impact of Immunosuppression Reduction on Allograft Rejection
A. Szczepanik¹, A. Bixby¹, C. Burrelli¹, A. Padiyar², T. Srinivas², K. Chavin³
¹Pharmacy, University Cleveland Medical Center, Cleveland, OH, ²Nephrology, University Cleveland Medical Center, Cleveland, OH, ³Surgery, University Cleveland Medical Center, Cleveland, OH
*Purpose: BK viremia (BKV) increases the risk of renal allograft loss following transplant. Guidelines recommend reduction of immunosuppression (IS) after BKV diagnosis, however, the ideal…
2020 American Transplant Congress
Effect of Discordant Kidney Function at Transplant: A Single Center Analysis of Deceased Donor Paired Kidneys
E. Abuhelaiqa¹, M. Alkadi¹, S. Mansour², L. Mathew¹, F. Makableh¹, A. Nauman¹, O. Fituri¹, M. Asim¹, R. Fadhil³, H. A. Al-Malki¹
¹Nephrology, Hamad Medical Corporation, Doha, Qatar, ²Internal Medicine, Hamad Medical Corporation, Doha, Qatar, ³Transplant Surgery, Hamad Medical Corporation, Doha, Qatar
*Purpose: Analysis of paired kidneys from deceased donors has the advantage of eliminating donor and center related biases seen in previous studies that evaluated kidney…
2020 American Transplant Congress
Hyperspectral Imaging of Human Kidney Allografts
R. Sucher¹, H. Köhler², A. Lederer¹, H. M. Hau¹, I. Gockel¹, D. Seehofer¹
¹Department of Visceral, Transplant-, Thoracic and Vascular Surgery, University Clinic Leipzig, Leipzig, Germany, ²Innovation Center for Computer Assisted Surgery, University Clinic Leipzig, Leipzig, Germany
*Purpose: Hyperspectral imaging (HSI) is capable to deliver non-contact, non-ionizing and non-invasive quantitative diagnostic information about tissue pathology, morphology and composition, based on the spectral…
2020 American Transplant Congress
The Impact of Epitope Mismatch Load and Shared Targeting Epitopes between De Novo Donor Specific Antibody (DSA) and Non-DSA Third Party HLA Antibody on Lung Transplantation Outcomes
A. Zhang¹, D. Good¹, D. Thomas¹, J. Allen¹, K. McCurry², M. Budev²
¹Allogen Laboratories, Cleveland Clinic, Cleveland, OH, ²Cleveland Clinic, Cleveland, OH
*Purpose: Rapid advancements in HLA typing and antibody identification technologies allow for enhanced HLA compatibility assessment at the epitope level to aid in the reduction…
2020 American Transplant Congress
Renal Allograft Outcome from Hypertensive Donor: Comparison between Living and Deceased Donor
H. Hwang¹, J. Kong¹, J. Kim¹, Y. Kim¹, J. Moon¹, K. Jeong¹, S. Song², S. Song³, H. Shin⁴, J. Yang⁵, C. Ahn⁶, Y. Lee⁷, S. Lee¹
¹Division of Nephrology, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea, Republic of, ²Pusan National University Hospital, Pusan, Korea, Republic of, ³Ewha Womans University Medical Center, Seoul, Korea, Republic of, ⁴Kosin University College of Medicine, Pusan, Korea, Republic of, ⁵Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ⁶Department of Nephrology, Seoul National University Hospital, Seoul, Korea, Republic of, ⁷Division of Nephrology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seoul, Korea, Republic of
*Purpose: Donor shortage is a serious problem in renal transplantation, and hypertensive living donor is potential candidates to expand donor pool. However, it is not…