Articles tagged "Graft function"

2021 American Transplant Congress
Allograft Function and Baseline Donor Derived Cell Free DNA in Kidney Transplant Recipients: One Size Doesn’t Fit All
K. K. Sureshkumar, A. Grazier, B. Chopra
Allegheny General Hospital, Allegheny Health Network, Pittsburgh, PA
*Purpose: Donor derived cell free DNA (dd-cfDNA) is increasingly used to predict acute rejection in kidney allografts . Cell free DNA fragments are constantly released…
2021 American Transplant Congress
Combined Heart-liver Transplantation in Patients with Familial Amyloidosis – Analysis of Optn/Unos Database
A. Sharma, A. Sickels, B. Ruch, M. Carli, M. Levy
Virginia Commonwealth University, Richmond, VA
*Purpose: We compared the outcomes after combined heart-liver transplant (CHLT) for patients with Familial Amyloidosis (FA) versus other indications (primary cardiac:congenital heart disease and idiopathic…
2021 American Transplant Congress
Transplant Center Volume in High-risk Recipient Association with Graft and Patient Survival
M. A. Merzkani, H. Murad, M. Mattu, S. Husami, M. Wang, V. Hu, S. Chang, T. Alhamad
Transplant, Washington University, Saint Louis, MO
*Purpose: Evaluation of high-risk recipients in transplant centers involves an intensive multidisciplinary medical evaluation and requires extensive coordination amongst various teams to follow-up on these…
2020 American Transplant Congress
Donor Kidney Perfusion Fluid Extracellular Vesicles as Markers of Graft Function
A. K. Rutman, S. Negi, N. Saberi, J. Tchervenkov, S. Paraskevas
Research Institute of the McGill University Health Institute, Montreal, QC, Canada
*Purpose: Kidney transplantation is a life-saving treatment for many patients with end-stage renal failure. Recently, machine perfusion of kidneys prior to transplantation has emerged as…
2020 American Transplant Congress
Rabbit Anti-Thymocyte Globulin versus Anti-T Lymphocyte Globulin Rescue Therapies in Delayed Graft Function after Kidney Transplantation from Donors after Cardiac Death
H. Yang¹, Y. Shi², X. Li¹, C. Long¹, H. Li³, Z. Wang³
¹Department of Organ Transplantation, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, China, ²Department of Pathology, Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, ³Department of Urologic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
*Purpose: Delayed graft function (DGF) is common in recipients of kidney transplants from donation after cardiac death (DCD) donors, induction therapy with monoclonal or polyclonal…
2020 American Transplant Congress
Estrogen Receptor Beta Deletion in the Vascular Endothelium is Protective in Renal Ischemia Reperfusion Injury
L. Krumeich¹, P. Hernandez¹, C. O'Brien¹, S. Concors¹, Z. Wang¹, G. Ge¹, W. Hancock², M. Levine¹
¹Hospital of University of Pennsylvania, Philadelphia, PA, ²Childrens Hospital of Philadelphia, Philadelphia, PA
*Purpose: Renal ischemia reperfusion injury (IRI) is a major contributor to early allograft dysfunction (EAD) in kidney transplantation. We previously identified lower rates of EAD…
2020 American Transplant Congress
Pattern of Renal Allograft Injury in Recipients with Normal Donor-Derived Cell-Free DNA
W. Xie, N. Goussous, A. Haririan, M. Weir, J. Bromberg
University of Maryland School of Medicine, Baltimore, MD
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a novel non-invasive test currently used as a biomarker for identification of transplant rejection or injury. Here, we sought…
2020 American Transplant Congress
The Impact of Deceased Donor Maintenance on the Incidence of Delayed Kidney Allograft Function
S. Costa¹, F. Barroso¹, C. Oliveira¹, E. Daher¹, P. Fernandes¹, L. Andrade², R. Esmeraldo³, T. Sandes-Freitas¹
¹Universidade Federal do Ceará, Fortaleza, Brazil, ²Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil, ³Hospital Geral de Fortaleza, Fortaleza, Brazil
*Purpose: To evaluate the risk factors for delayed graft function (DGF) in a Brazilian cohort with high DGF incidence, focusing on variables reflecting donor maintenance.*Methods:…
2020 American Transplant Congress
Improving Evaluation and Follow-Up of Living Kidney Donors: Role of Radioisotopic Glomerular Filtration Rate and Renal Functional Reserve
V. Cantaluppi¹, G. Guglielmetti¹, U. M. Morosini¹, A. Nappo¹, G. Merlotti¹, A. Airoldi¹, M. Quaglia¹, C. Ronco²
¹Nephrology and Kidney Transplantation Unit, University of Piemonte Orientale (UPO), Novara, Italy, ²Nephrology, Dialysis and Kidney Transplantation Unit, University of Padova, Vicenza, Italy
*Purpose: After donation, living kidney donors (KD) develop an early and transient loss of kidney function (KF), defined as Acute Kidney Injury (AKI). Its recovery…
2020 American Transplant Congress
Gross Morphological Score for Deceased Donor Kidneys Can Predict Delayed Graft Function in Kidney Transplant Recipients
M. Mandurah, M. A. Levine, A. Sener, P. Luke
Department of Kidney Transplantation, London Health Sciences Center, London, ON, Canada
*Purpose: Both microscopy and kidney donor profile index (KDPI) scoring systems have been used to predict kidney transplant outcomes. Utilizing gross renal morphology, we designed…