Articles tagged "Graft function"

2021 American Transplant Congress
Comparative Proteomics Analysis Identifies the Biomarker of Ischemia-Reperfusion Injury During Liver Transplantation
M. Chen¹, L. Xiaohong², H. Xitao¹, J. Weiqiang¹
¹Transplant Center, Sun Yat-sen University, Guangzhou, China, ²Sun Yat-sen University, Guangzhou, China
*Purpose: To a large extent the success of liver transplantation depends on quality of allografts. The molecular basis of the susceptibility of different liver allografts…
2021 American Transplant Congress
Evaluation of the Impact of Delayed Graft Function (dgf) on Kidney Allograft Outcomes
J. Leeds, B. Rawashdeh, M. Sestito, B. Sharma, J. Kamal, A. Kumar, A. AgarwalAA4VB, A. Doyle, S. Rao
University of Virginia, Charlottesville, VA
*Purpose: DGF is an important post-transplant complication that has early and long-term consequences on graft survival with increased relative risk of graft loss. DGF frequency…
2021 American Transplant Congress
Feasibility of Normothermic Ex Vivo Kidney Perfusion for Human Kidney Transplantation: First North American Results
L. I. Mazilescu¹, P. Urbanellis¹, J. S. Kim¹, A. Konvalinka¹, T. W. Reichman¹, L. A. Robinson², A. Ghanekar¹, M. Selzner¹
¹Ajmera Transplant Program, Toronto General Hospital, Toronto, ON, Canada, ²Department of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: Normothermic ex vivo kidney perfusion is a novel preservation technique with promising results in porcine models and initial clinical results in one European center.…
2021 American Transplant Congress
Intraoperative Fluid Management and Kidney Transplantation Outcomes: A Retrospective Review
M. W. Harbell¹, M. B. Kraus¹, S. A. Buckner Petty², J. W. Harbell³
¹Anesthesiology and Perioperative Medicine, Mayo Clinic, Phoenix, AZ, ²Biostatistics, Mayo Clinic, Phoenix, AZ, ³Transplant Surgery, Mayo Clinic, Phoenix, AZ
*Purpose: Patients undergoing kidney transplantation have traditionally received liberal amounts of fluid during surgery to ensure adequate fluid volume and flow to the transplanted kidney.…
2021 American Transplant Congress
A2 to B Deceased Donor Renal Transplantation Outcome Analysis: Single Center Experience
S. Bindroo, M. Doshi
Nephrology, University of Michigan, Ann Arbor, MI
*Purpose: Initial experience under kidney allocation system (KAS) implemented in December 2014 showed equivalent outcomes for A2 to B kidney transplantation compared with ABO compatible…
2021 American Transplant Congress
Multistep Algorithm to Achieve Weight Loss Goal in Advanced Stage Obesity Kidney Transplant Candidates: A Single Center Preliminary Report
A. Shah, J. Galpern, L. Castaldo, P. Touhy, M. Thomas, A. Aaron, M. Fruscione, L. Dageforde, N. Elias
Transplant Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: Obesity causes and complicates glomerulonephritis and chronic kidney disease (CKD) leading to end stage renal disease (ESRD). Kidney Transplantation (KT) improves ESRD patients’ survival…
2021 American Transplant Congress
The Role of the B2 Microglobulin Trend in Patients with Delayed Graft Function After Kidney Transplant
A. Perez-Gutierrez, P. J. Bachul, B. Juengel, P. Witkowski, D. DiSabato, R. Barth, J. Fung, Y. Becker
Surgery, University of Chicago, Chicago, IL
*Purpose: Delayed graft function (DGF) is associated with worse short and long-term outcomes after kidney transplantation. There is a lack of biomarkers to predict outcomes…
2021 American Transplant Congress
The Role of Donor-derived Cell-free DNA Testing in Detecting Subclinical Kidney Allograft Rejection
M. Dasari¹, J. Hendele², L. Sibulesky², N. Leca³
¹Department of Surgery, University of Washington, Seattle, WA, ²Department of Surgery, Division of Transplant, University of Washington, Seattle, WA, ³Department of Nephrology, UW Medicine Kidney and Pancreas Transplantation Program, University of Washington, Seattle, WA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) testing is an emerging method of non-invasive testing for graft rejection in the field of solid-organ transplantation. We describe how…
2021 American Transplant Congress
Cellular Landscape of Steatotic Livers Revealed by Single-nuclei Rna Sequencing
C. Kuscu¹, C. Kuscu¹, A. Shetty², E. Bardhi³, T. Rousselle⁴, J. Eason¹, M. Sraj⁵, D. Maluf⁶, V. Mas⁴
¹Surgery, James D Eason Transplant Institute, Memphis, TN, ²University of Maryland, Institute for Genome Sciences, Baltimore, MD, ³Program in Transplantation - University of Maryland, Baltimore, MD, ⁴Surgery, Division of Surgical Science, Baltimore, MD, ⁵Surgery, University of Maryland, Baltimore, MD, ⁶Surgery, Program in Transplantation - University of Maryland, Baltimore, MD
*Purpose: Hepatic IRI represents a barrier to the use of available organs for transplant, particularly fatty livers. We aimed to discern the cellular subsets and…
2021 American Transplant Congress
Role of Trugraf Testing in Kidney Allografts Previously Biopsied for Dysfunction
Y. A. Qazi¹, W. Mon¹, C. Choi¹, S. Qazi², M. Smogorzewski¹
¹Keck Medical Center at USC, Los Angeles, CA, ²Keck Medical Center at USC, La Canada Flt, CA
*Purpose: TruGraf®, can be used as an alternative to surveillance biopsies for ruling out “silent” subclinical acute rejections in transplant patients with stable graft function.…

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