ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2022 American Transplant Congress

    Is Donor Hepatitis C Virus Infection Status Associated with Early Post-Kidney Transplant Failure in the Era of Direct-Acting Antiviral Medications?

    S. Sutcliffe1, S. Chang1, D. Stewart2, M. Ji3, K. Lentine4, G. Gupta5, T. Alhamad6

    1Washington University School of Medicine, Saint Louis, MO, 2United Network for Organ Sharing, Richmond, VA, 3Washington University in St. Louis School of Medicine, Saint Louis, MO, 4Saint Louis University School of Medicine, Saint Louis, MO, 5Virginia Commonwealth University School of Medicine, Richmond, VA, 6Washington University School of Medicine at St. Louis, Saint Louis, MO

    *Purpose: To determine the influence of donor hepatitis C virus (HCV) infection status on early kidney transplant (KT) failure in HCV negative recipients in the…
  • 2022 American Transplant Congress

    Donor Factors Do Not Discriminate Living Donor Kidney Transplant Outcomes and Should Not Be Used to Promote the Use of Compatible Pairs in Kidney Paired Donation Programs

    G. Irish1, D. Chang2, S. Chadban1, N. Boudville1, S. Campbell1, J. Kanellis1, L. McMichael2, E. Sharples3, M. Kadatz2, J. Gill2, P. Clayton1

    1ANZDATA, Adelaide, Australia, 2Providence Health Research Institute, Transplant Research, Vancouver, BC, Canada, 3Oxford University Trust Hospital, Oxford, United Kingdom

    *Purpose: Enrolment of ABO blood group and HLA incompatible pairs in kidney paired donation programs improves matching potential. The benefit for compatible pairs, however, is…
  • 2022 American Transplant Congress

    Assessing Proportion of Days Covered (PDC) of Mycophenolate (MCP) Prescriptions in Post Kidney Transplant (KT) Recipients as a Predictor of Clinical Outcomes

    K. Sandlin1, T. Sam1, N. Wilson1, A. Yango2, B. Fischbach3, A. Dao1

    1Pharmacy, Baylor University Medical Center, Dallas, TX, 2Baylor All Saints Medical Center, Dallas Nephrology Associates, Fort Worth, TX, 3Baylor University Medical Center, Dallas Nephrology Associates, Dallas, TX

    *Purpose: Nonadherence to medications following KT is a risk factor for adverse outcomes. PDC is an objective measure of adherence obtained through retail prescription records…
  • 2022 American Transplant Congress

    Association Between Increased Overweight at First Year After Kidney Transplantation and Long-Term Kidney Graft Outcome

    H. Choi1, K. Huh2, K. B. Seok3

    1Yonsei University College of Medicine, Seoul, Korea, Republic of, 2Department of Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of, 3Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of

    *Purpose: The obesity is increasing in chronic kidney disease patients and associated with poor renal outcome. The role of inflammation within the adipose tissue in…
  • 2022 American Transplant Congress

    Pancreatic Islets Engineered with Thrombomodulin Show Enhanced Engraftment in an Intraportal Transplantation Model by Mitigating Instant Blood-Mediated Inflammatory Reactions

    A. Turan1, L. Zhang2, M. Tarique2, V. Ulker2, E. Yolcu3, H. Shirwan3

    1Molecular Microbiology and Immunology, University of Missouri at Columbia, Columbia, MO, 2Department of Child Health, University of Missouri at Columbia, Columbia, MO, 3Child Health and Molecular Microbiology and Immunology, University of Missouri at Columbia, Columbia, MO

    *Purpose: IBMIR is a major culprit of early islet loss post-transplant. Thrombomodulin (TM) is an anti-coagulant and cofactor of activated Protein C (APC) that perpetuates…
  • 2022 American Transplant Congress

    Recipient Race Modifies the Association Between Obesity and Long Term Graft Outcomes After Renal Transplantation

    F. Jarrar1, K. Tennankore2, A. J. Vinson3

    1Dalhousie University, Halifax, NS, Canada, 2Nova Scotia Health Authority, Halifax, NS, Canada, 3Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada

    *Purpose: Both donor and recipient obesity are associated with adverse outcomes after transplant. Whether obesity, defined using body mass index (BMI), has different implications on…
  • 2022 American Transplant Congress

    HLA-DQ Mismatches Are More Likely to Be Listed as Unacceptable Antigens After Renal Graft Failure in African American Recipients as Compared to Other Racial/Ethnic Groups

    D. Isaacson1, M. W. Gmeiner2, V. Kosmoliaptsis3, J. D. Schold4, A. R. Tambur1

    1Northwestern University, Chicago, IL, 2London School of Economics, London, United Kingdom, 3Cambridge University, Cambridge, United Kingdom, 4Cleveland Clinic, Cleveland, OH

    *Purpose: Growing evidence suggests that donor-recipient mismatches at the HLA-DQ locus are the most immunogenic and pathogenic, evidenced by generation of DQ donor-specific antibodies (DSA).…
  • 2022 American Transplant Congress

    Impact of HLA Matching on Graft Survival in Kidney Transplant Recipients

    J. Miller1, N. Salkowski1, B. Thompson1, R. Kandaswamy2, P. Stock3, A. Israni1

    1Scientific Registry of Transplant Recipients, Minneapolis, MN, 2Department of Surgery, University of Minnesota Medical School, Minneapolis, MN, 3Department of Surgery, University of California San Francisco, San Francisco, CA

    *Purpose: This study aims to estimate the association of HLA matching at the A, B, DR, and DQ loci with posttransplant graft failure and patient…
  • 2022 American Transplant Congress

    Interventional Radiology Procedures for Complications of Orthotopic Liver Retransplantation: A 22-year Single Center Experience

    A. F. Sayed Ahmed1, B. B. Toskich1, S. A. Mao2

    1Interventional Radiology, Mayo Clinic, Jacksonville, FL, 2Transplant Surgery, Mayo Clinic, Jacksonville, FL

    *Purpose: Liver retransplantation (re-OLT) represents a high risk, resource intense, operation for recipients with failed allografts. We review our single center 22-year experience with re-OLT…
  • 2022 American Transplant Congress

    Autologous Mesenchymal Stem Cells for Treatment of Chronic Antibody-Mediated Kidney Graft Rejection: Report of the First Phase I/II Clinical Case Series

    Ž. Večerić-Haler1, M. Sever2, N. Kojc3, G. Mlinšek1, M. Oblak1, P. Halloran4, A. Aleš Rigler1, J. Buturović Ponikvar1, M. Arnol5

    1Nephrology, UMC Ljubljans, Ljubljana, Slovenia, 2Haematology, UMC Ljubljans, Ljubljana, Slovenia, 3Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana,, Ljubljana, Slovenia, 4Division of Nephrology and Transplant Immunology, University of Alberta, Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 5University Medical Centre Ljubljana, Ljubljana, Slovenia

    *Purpose: The aim of this study is to evaluate the safety and efficacy of autologous mesenchymal stem cellc (MSCs) in combination with standard of care…
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